Daniel Boyd Kramer

Unsustainable hunting, both illegal and legal, has led to the extirpation of many species. In the last 35 years giraffeGiraffaspp. populations have declined precipitously, with extinctions documented in seven African countries. Amongst the various reasons for these population declines, poaching is believed to play an important role in some areas. Giraffes are primarily hunted for consumption and for the use of their body parts as trophies and in traditional medicine. However, the socio-economic factors that correlate with the use of giraffe body parts are not well understood. We conducted our study in Tsavo Conservation Area, Kenya, which experiences high levels of poaching. We used semi-structured surveys amongst 331 households to document how giraffe body parts are typically acquired and their intended use (i.e. trophy, medicinal or consumptive). We then used logistic regression models to assess the correlations between nine socio-economic factors and the use of giraffe body parts. We found that giraffe body parts had mostly consumptive and trophy uses. One-time suppliers, opportunistic access and widely known markets were the most common means of acquiring giraffe body parts. Results from our models showed that three variables (gender: men, occupation: tourism worker, and land ownership) were correlated significantly and positively with the use of giraffe body parts. We describe the complex links between socio-economic factors and the use of giraffe body parts and highlight the importance of implementing mitigation measures adapted to local contexts to combat a challenge that many species of conservation concern are facing.

Background: This study compared the efficacy, safety, and immunogenicity of insulin aspart biosimilar/follow-on biologic product SAR341402 (SAR-Asp) with originator insulin aspart-NovoLog ^® /NovoRapid ^® (NN-Asp) in people with type 1 diabetes (T1D) or type 2 diabetes (T2D) treated with multiple daily injections in combination with insulin glargine (Lantus ^® ; Gla-100). Materials and Methods: This 6-month, randomized, open-label, phase 3 study (NCT03211858) enrolled 597 people with T1D ( n = 497) or T2D ( n = 100). Participants were randomized 1:1 to mealtime SAR-Asp ( n = 301) or NN-Asp ( n = 296) in combination with Gla-100. The primary objective was to demonstrate noninferiority (by 0.3% margin in the intent-to-treat population) of SAR-Asp versus NN-Asp in HbA1c change from baseline to week 26. Immunogenicity was also assessed in terms of anti-insulin aspart antibody (AIA) status (positive/negative) and titers during the study. Results: HbA1c was similarly improved in both treatment groups (SAR-Asp −0.38%; NN-Asp −0.30%); the least squares mean difference at week 26 for SAR-Asp minus NN-Asp was −0.08% (95% confidence interval: −0.192 to 0.039), thus meeting the criteria for noninferiority between SAR-Asp and NN-Asp and inverse noninferiority of NN-Asp versus SAR-Asp. Changes in fasting plasma glucose and seven-point self-monitored plasma glucose profile, including postprandial glucose excursions, and insulin dosages were similar in both groups at week 26. Safety and tolerability, including AIA responses (incidence, prevalence), hypoglycemia, and adverse events (including hypersensitivity events and injection site reactions), were similar between groups. Conclusions: SAR-Asp demonstrated effective glycemic control with a similar safety and immunogenicity profile to NN-Asp in people with diabetes treated for 26 weeks.

In this paper, we examine the benefits and costs of hydropower development in the Mekong River Basin. We compare four major reports—the Mekong River Commission's (MRC's) Basin Development Plan Programme, Phase 2 (BDP2), the Strategic Environmental Assessment of Hydropower on the Mekong Mainstream (SEA), the Study on the Impacts of Mainstream Hydropower on the Mekong River (MDS), and the MRC's recent council study (CS)—in order to provide the basis for a comparative analysis of the major impact evaluation literature on mainstream dam construction in the Mekong River Basin for the period of 2010–2018. The primary objective of the review is to identify points of agreement, disagreement, inconsistency, and knowledge gaps. Both Mekong River Commission reports (BDP2 and CS) suggest extensive economic benefits for proposed hydropower development, whereas the SEA and MDS indicate that the net impact would be negative. The projected impacts of hydropower development on fisheries, sediment flows, and ecosystems vary widely both in economic and biophysical terms. However, all four reports point to decreased food security and loss of local livelihoods for millions of people as major concerns related to dam development. While considerable resources have been devoted to producing these important studies, the lack of standardization across reports, especially assumptions and methodologies for economic impacts, frustrates efforts at meaningful comparison of their findings and precludes the prospect of clear analytical outcomes or policy impacts.This article is categorized under: Engineering Water > Planning Water Human Water > Value of Water Engineering Water > Methods

Anthropogenic threats to natural systems can be exacerbated due to connectivity between marine, freshwater, and terrestrial ecosystems, complicating the already daunting task of governance across the land-sea interface. Globalization, including new access to markets, can change social-ecological, land-sea linkages via livelihood responses and adaptations by local people. As a first step in understanding these trans-ecosystem effects, we examined exit and entry decisions of artisanal fishers and smallholder farmers on the rapidly globalizing Caribbean coast of Nicaragua. We found that exit and entry decisions demonstrated clear temporal and spatial patterns and that these decisions differed by livelihood. In addition to household characteristics, livelihood exit and entry decisions were strongly affected by new access to regional and global markets. The natural resource implications of these livelihood decisions are potentially profound as they provide novel linkages and spatially-explicit feedbacks between terrestrial and marine ecosystems. Our findings support the need for more scientific inquiry in understanding trans-ecosystem tradeoffs due to linked-livelihood transitions as well as the need for a trans-ecosystem approach to natural resource management and development policy in rapidly changing coastal regions.

Kramer, D. B., J. Hartter, A. E. Boag, M. Jain, K. Stevens, K. Ann Nicholas, W. J. McConnell, and J. Liu. 2017. Top 40 questions in coupled human and natural systems (CHANS) research. Ecology and Society 22(2):44. https://doi.org/10.5751/ES-09429-220244

Small-scale fisheries (SSF) employ 90 percent of the world's fishers, account for 50 percent of the world's catch, and are essential to the livelihoods, food security, and well-being of many in the...