Edgar Garcia-Rill
Current Organizations / Institutes
The organizations/institutes from the scholar's latest article
Previous Organizations / Institutes
The organizations / institutes from the scholar's other articles in the past ten years
Research Subjects
Edgar Garcia-Rill has a total of 334 co-authors. Here are the top co-authors by number of shared publications:
R.D. Skinner
Center for Translational Neuroscience, Department of Neurobiology and Developmental Sciences, University of Arkansas for Medical Sciences, Little Rock, AR, United States
38 shared publicationsFrancisco J. Urbano
Instituto de Investigaciones Farmacológicas, Universidad de Buenos Aires, Buenos Aires, Argentina
28 shared publicationsRobert D. Skinner
Center for Translational Neuroscience, Department of Neurobiology and Developmental Sciences, University of Arkansas for Medical Sciences Little Rock, AR, USA
21 shared publicationsR. D. Skinner
Neurobiology & Developmental Sciences, University of Arkansas for Medical Sciences, Little Rock, AR
15 shared publicationsJames Hyde
Department of Psychiatry and Center for Neural Basis of Cognition, University of Pittsburgh, Pittsburgh, Pennsylvania
11 shared publicationsChristen Simon
A Center for Translational Neuroscience, Department of Neurobiology & Dev. Sci., University of Arkansas for Medical Sciences, 4301 West Markham St., Slot 847, Little Rock, AR 72205, USA
10 shared publications
Latest Publications
- 1 January 2022
- Published by Elsevier
- p. 101-110
Deep brain stimulation for understanding the sleep-wake phenomena
- 1 January 2022
- Published by Elsevier
- p. 101-110
Deep brain stimulation for understanding the sleep-wake phenomena
- 1 March 2020
- Published by Elsevier in Neuropharmacology
- Vol. 165, 107922
Differential effects of HDAC inhibitors on PPN oscillatory activity in vivo
- 1 March 2020
- Published by Elsevier in Neuropharmacology
- Vol. 165, 107922
Differential effects of HDAC inhibitors on PPN oscillatory activity in vivo
- 1 February 2020
- Published by American Physiological Society in American Journal of Physiology-Cell Physiology
- Vol. 318 (2) , C282-C288
Gamma oscillations in the pedunculopontine nucleus are regulated by F-actin: neuroepigenetic implications
The pedunculopontine nucleus (PPN) is part of the reticular activating system (RAS) in charge of arousal and rapid eye movement sleep. The presence of high-frequency membrane oscillations in the gamma-band range in the PPN has been extensively demonstrated both in vivo and in vitro. Our group previously described histone deacetylation (HDAC) inhibition in vitro induced protein changes in F-actin cytoskeleton and intracellular Ca2+ concentration regulation proteins in the PPN. Here, we present evidence that supports the presence of a fine balance between HDAC function and calcium calmodulin kinase II-F-actin interactions in the PPN. We modified F-actin polymerization in vitro by using jasplakinolide (1 μM, a promoter of F-actin stabilization), or latrunculin-B (1 μM, an inhibitor of actin polymerization). Our results showed that shifting the balance in either direction significantly reduced PPN gamma oscillation as well as voltage-dependent calcium currents.
- 1 February 2020
- Published by American Physiological Society in American Journal of Physiology-Cell Physiology
- Vol. 318 (2) , C282-C288
Gamma oscillations in the pedunculopontine nucleus are regulated by F-actin: neuroepigenetic implications
The pedunculopontine nucleus (PPN) is part of the reticular activating system (RAS) in charge of arousal and rapid eye movement sleep. The presence of high-frequency membrane oscillations in the gamma-band range in the PPN has been extensively demonstrated both in vivo and in vitro. Our group previously described histone deacetylation (HDAC) inhibition in vitro induced protein changes in F-actin cytoskeleton and intracellular Ca2+ concentration regulation proteins in the PPN. Here, we present evidence that supports the presence of a fine balance between HDAC function and calcium calmodulin kinase II-F-actin interactions in the PPN. We modified F-actin polymerization in vitro by using jasplakinolide (1 μM, a promoter of F-actin stabilization), or latrunculin-B (1 μM, an inhibitor of actin polymerization). Our results showed that shifting the balance in either direction significantly reduced PPN gamma oscillation as well as voltage-dependent calcium currents.
- 1 January 2020
- Published by Elsevier in Neuropharmacology
- Vol. 162, 107787
The critical role of persistent sodium current in hippocampal gamma oscillations
- 1 January 2020
- Published by Elsevier in Neuropharmacology
- Vol. 162, 107787
The critical role of persistent sodium current in hippocampal gamma oscillations
- Open Access
- 15 October 2019
- Published by Wiley in Journal of Neuroscience Research
- Vol. 97 (12) , 1749
My years at UCLA
- 15 October 2019
- Published by Wiley in Journal of Neuroscience Research
- Vol. 97 (12) , 1749
Open AccessMy years at UCLA
- 30 September 2019
- Published by Springer Nature in Cellular and Molecular Life Sciences
- Vol. 76 (23) , 4581-4582
Concerns regarding Baksa B, Kovacs A, Bayasgalan T, Szentesi P, Koseghy A, Szucs P, Balazs P. Characterization of functional subgroups among genetically identified cholinergic neurons in the pedunculopontine nucleus. Cell Molec. Life Sci. 2019-04-02
- 30 September 2019
- Published by Springer Nature in Cellular and Molecular Life Sciences
- Vol. 76 (23) , 4581-4582
Concerns regarding Baksa B, Kovacs A, Bayasgalan T, Szentesi P, Koseghy A, Szucs P, Balazs P. Characterization of functional subgroups among genetically identified cholinergic neurons in the pedunculopontine nucleus. Cell Molec. Life Sci. 2019-04-02
- Open Access
Proteomic measures of gamma oscillations
- 1 August 2019
- Published by Elsevier in Neurobiology of Disease
- Vol. 128, 31-39
Bottom-up gamma maintenance in various disorders
- 1 August 2019
- Published by Elsevier in Neurobiology of Disease
- Vol. 128, 31-39
Bottom-up gamma maintenance in various disorders
- 1 June 2019
- Published by Elsevier in Clinical Neurophysiology
- Vol. 130 (6) , 925-940
Focus on the pedunculopontine nucleus. Consensus review from the May 2018 brainstem society meeting in Washington, DC, USA
- 1 June 2019
- Published by Elsevier in Clinical Neurophysiology
- Vol. 130 (6) , 925-940
Focus on the pedunculopontine nucleus. Consensus review from the May 2018 brainstem society meeting in Washington, DC, USA