Nadine Karlsson
Current Organizations / Institutes
The organizations/institutes from the scholar's latest article
Research Subjects
Research Interests
Nadine Karlsson has a total of 63 co-authors. Here are the top co-authors by number of shared publications:
- Preben Bendtsen
Department of Health, Medicine and Caring Sciences, Linkoping University, Linkoping, Östergötland, Sweden
9 shared publications - Marcus Bendtsen
Department of Health, Medicine and Caring Sciences, Linkoping University, Linkoping, Östergötland, Sweden
7 shared publications - Ian R. White
Affiliation MRC Clinical Trials Unit at University College London, London, United Kingdom
4 shared publications - Jim McCambridge
University of York, York, UK
4 shared publications - Kristin Thomas
Department of Health, Medicine and Caring Sciences, Linköping University, Linköping, Sweden
4 shared publications - Ulrika Müssener
Department of Health, Medicine, and Caring Sciences, Linköping University, Linköping, Östergötland, Sweden
4 shared publications
Latest Publications
- Open Access
- 8 July 2026
- Published by BMJ in Open Heart
- Vol. 13 (2) , e004130
Prognostic value of baseline and longitudinal changes in exercise capacity and quality of life in the HF-Wii Swedish population
This study aimed to explore whether baseline values and 12-month change in the 6-Minute Walk Distance (6MWD) and the physical scale of the Minnesota Living with Heart Failure Questionnaire (MLHFQ) were associated with long-term mortality in patients with heart failure (HF). Methods: A total of 333 patients with HF, enrolled in the HF-Wii trial ( NCT01785121 ) in Sweden, were included. Data on long-term mortality were gathered 3 years after study completion of the last patient included. Study participants were stratified into three groups based on baseline results of the 6MWD: group 1: ≤383 m, group 2: 384–450 m and group 3: ≥451 m. Similarly, tertiles were formed according to baseline MLHFQ physical domain scores: group 1: 0–5 points, group 2: 6–12 points and group 3: 13–40 points. Results: During a median (25th–75th percentiles) follow-up of 1900 (1566, 2271) days, 48 patients died (14.4%). Patients in group 1 of 6MWD displayed a more severe clinical status in comparison to patients in groups 2 and 3. Kaplan-Meier survival analysis showed a statistically significant between-group difference in survival, observed per tertile groups of the baseline 6MWD. However, no significant difference in survival was found in relation to changes in 6MWD over time. Likewise, there were not statistically significant between-group differences in survival per tertile groups of the baseline score on the physical domain of MLHFQ nor with respect to change over time of the same score. Conclusions: Baseline 6MWD demonstrated significant prognostic value for long-term mortality in patients with HF whereas the physical score of MLHFQ, as well as their 12-month changes did not reach statistical significance. Trial registration number: NCT01785121 .
- 8 July 2026
- Published by BMJ in Open Heart
- Vol. 13 (2) , e004130
Open AccessPrognostic value of baseline and longitudinal changes in exercise capacity and quality of life in the HF-Wii Swedish population
This study aimed to explore whether baseline values and 12-month change in the 6-Minute Walk Distance (6MWD) and the physical scale of the Minnesota Living with Heart Failure Questionnaire (MLHFQ) were associated with long-term mortality in patients with heart failure (HF). Methods: A total of 333 patients with HF, enrolled in the HF-Wii trial ( NCT01785121 ) in Sweden, were included. Data on long-term mortality were gathered 3 years after study completion of the last patient included. Study participants were stratified into three groups based on baseline results of the 6MWD: group 1: ≤383 m, group 2: 384–450 m and group 3: ≥451 m. Similarly, tertiles were formed according to baseline MLHFQ physical domain scores: group 1: 0–5 points, group 2: 6–12 points and group 3: 13–40 points. Results: During a median (25th–75th percentiles) follow-up of 1900 (1566, 2271) days, 48 patients died (14.4%). Patients in group 1 of 6MWD displayed a more severe clinical status in comparison to patients in groups 2 and 3. Kaplan-Meier survival analysis showed a statistically significant between-group difference in survival, observed per tertile groups of the baseline 6MWD. However, no significant difference in survival was found in relation to changes in 6MWD over time. Likewise, there were not statistically significant between-group differences in survival per tertile groups of the baseline score on the physical domain of MLHFQ nor with respect to change over time of the same score. Conclusions: Baseline 6MWD demonstrated significant prognostic value for long-term mortality in patients with HF whereas the physical score of MLHFQ, as well as their 12-month changes did not reach statistical significance. Trial registration number: NCT01785121 .
- Open Access
- 1 January 2024
- Published by Wiley in Journal of Nursing Management
- Vol. 2024 (1) , 2786600
A Cross‐Sectional Survey of Swedish Primary Healthcare Nurses’ Discontent With Their Current Job
Nursing staff turnover is an increasing problem for healthcare globally. In Sweden, the shortage of nurses in primary healthcare has increased significantly in recent years. This development is alarming because primary healthcare, both in Sweden and internationally, is responsible for a large part of healthcare. The aim of this study was to explore working conditions (change fatigue, leadership climate, and social support from colleagues) and characteristics of primary care nurses who are discontent with their current job, i.e., those with high turnover intentions and poor job satisfaction in Sweden. This was a cross‐sectional survey of 466 registered nurses working in Swedish primary healthcare. Data were analyzed using descriptive statistics and logistic regression. The results demonstrate that 21.1% of the responding nurses are discontent with their current job and have considered quitting. Being discontent had significant associations with poor leadership climate (p < 0.001), lack of social support from colleagues (p < 0.001), change fatigue (p < 0.001), poor health (p < 0.001), and working more than 40 h per week (p = 0.02). The results have implications for how healthcare organizations structure the work of nurses in primary healthcare and how they can attract and retain future staff to these workplaces.
- 1 January 2024
- Published by Wiley in Journal of Nursing Management
- Vol. 2024 (1) , 2786600
Open AccessA Cross‐Sectional Survey of Swedish Primary Healthcare Nurses’ Discontent With Their Current Job
Nursing staff turnover is an increasing problem for healthcare globally. In Sweden, the shortage of nurses in primary healthcare has increased significantly in recent years. This development is alarming because primary healthcare, both in Sweden and internationally, is responsible for a large part of healthcare. The aim of this study was to explore working conditions (change fatigue, leadership climate, and social support from colleagues) and characteristics of primary care nurses who are discontent with their current job, i.e., those with high turnover intentions and poor job satisfaction in Sweden. This was a cross‐sectional survey of 466 registered nurses working in Swedish primary healthcare. Data were analyzed using descriptive statistics and logistic regression. The results demonstrate that 21.1% of the responding nurses are discontent with their current job and have considered quitting. Being discontent had significant associations with poor leadership climate (p < 0.001), lack of social support from colleagues (p < 0.001), change fatigue (p < 0.001), poor health (p < 0.001), and working more than 40 h per week (p = 0.02). The results have implications for how healthcare organizations structure the work of nurses in primary healthcare and how they can attract and retain future staff to these workplaces.
- Open Access
- 24 March 2023
- Published by Frontiers Media SA in International Journal of Public Health
- Vol. 68
Relationship Between Educational Level and Attitudes Towards Alcohol Conversations in Healthcare: A Cross-Sectional Survey Conducted in Four European Countries
Objectives: To examine the association between educational level and attitudes towards alcohol conversations in healthcare using population-based surveys of adults in England, the Netherlands, Norway, and Sweden; and to compare attitudes towards alcohol conversations in healthcare between these four countries.Methods: Cross-sectional surveys were conducted amongst adults in the general population in England (n = 3,499), the Netherlands (n = 2,173), Norway (n = 1,208), and Sweden (n = 3,000). Logistic regression analysis was used to examine associations between attitudes towards alcohol conversations in healthcare and educational level, key demographic variables, alcohol consumption, and country of residence.Results: In all four countries, low educational level (p < 0.001) and male gender (p < 0.001) were associated with holding negative attitudes towards discussing alcohol in healthcare. Risky drinkers had more negative attitudes than low risky drinkers towards discussing alcohol in healthcare (p < 0.001) in all countries except England (p = 0.48), and also reported low levels of perceived honesty and confidence in healthcare (p < 0.001).Conclusion: These findings highlight the importance of considering patients’ socio-economic status when developing and implementing alcohol prevention interventions in healthcare.
- 24 March 2023
- Published by Frontiers Media SA in International Journal of Public Health
- Vol. 68
Open AccessRelationship Between Educational Level and Attitudes Towards Alcohol Conversations in Healthcare: A Cross-Sectional Survey Conducted in Four European Countries
Objectives: To examine the association between educational level and attitudes towards alcohol conversations in healthcare using population-based surveys of adults in England, the Netherlands, Norway, and Sweden; and to compare attitudes towards alcohol conversations in healthcare between these four countries.Methods: Cross-sectional surveys were conducted amongst adults in the general population in England (n = 3,499), the Netherlands (n = 2,173), Norway (n = 1,208), and Sweden (n = 3,000). Logistic regression analysis was used to examine associations between attitudes towards alcohol conversations in healthcare and educational level, key demographic variables, alcohol consumption, and country of residence.Results: In all four countries, low educational level (p < 0.001) and male gender (p < 0.001) were associated with holding negative attitudes towards discussing alcohol in healthcare. Risky drinkers had more negative attitudes than low risky drinkers towards discussing alcohol in healthcare (p < 0.001) in all countries except England (p = 0.48), and also reported low levels of perceived honesty and confidence in healthcare (p < 0.001).Conclusion: These findings highlight the importance of considering patients’ socio-economic status when developing and implementing alcohol prevention interventions in healthcare.
- Open Access
- 11 March 2021
- Published by SAGE Publications in Nordic Studies on Alcohol and Drugs
- Vol. 38 (3) , 243-255
Public perceptions of how alcohol consumption is dealt with in Swedish and Norwegian health care
The aims of this study were to evaluate and compare popular beliefs and attitudes regarding alcohol conversations in healthcare in Sweden and Norway; and to explore which factors were associated with different levels of support for alcohol-prevention work in the two countries. Population-based cross-sectional surveys were conducted in Sweden (n = 3000) and Norway (n = 1208). Logistic regression was used to identify the characteristics of participants who were supportive of routine alcohol screening and brief intervention delivery. A higher proportion of Swedish respondents agreed to a large extent that healthcare professionals should routinely ask about alcohol consumption. In addition, a higher proportion of Swedish respondents compared to respondents from Norway agreed that healthcare providers should only ask about patient’s alcohol consumption if this was related to specific symptoms. There were similar correlates of being supportive of routine alcohol screening and brief intervention delivery in both countries. Support was lower in both countries amongst moderate and risky drinkers, and among single adults or those on parental leave, but higher amongst older individuals. Having had an alcohol conversation in healthcare increased the level of support for alcohol prevention in routine healthcare among risky drinkers. There is a high level of support for preventative alcohol conversations in routine healthcare in Norway and Sweden, although there was a lower proportion of respondents who were positive to alcohol prevention in routine healthcare in Norway compared to Sweden. Experiencing alcohol conversation may positively affect risky drinkers’ attitudes towards and support for alcohol prevention. Thus, more frequent alcohol conversations in routine healthcare may also result in increased level of support for alcohol prevention among risky drinkers.
- 11 March 2021
- Published by SAGE Publications in Nordic Studies on Alcohol and Drugs
- Vol. 38 (3) , 243-255
Open AccessPublic perceptions of how alcohol consumption is dealt with in Swedish and Norwegian health care
The aims of this study were to evaluate and compare popular beliefs and attitudes regarding alcohol conversations in healthcare in Sweden and Norway; and to explore which factors were associated with different levels of support for alcohol-prevention work in the two countries. Population-based cross-sectional surveys were conducted in Sweden (n = 3000) and Norway (n = 1208). Logistic regression was used to identify the characteristics of participants who were supportive of routine alcohol screening and brief intervention delivery. A higher proportion of Swedish respondents agreed to a large extent that healthcare professionals should routinely ask about alcohol consumption. In addition, a higher proportion of Swedish respondents compared to respondents from Norway agreed that healthcare providers should only ask about patient’s alcohol consumption if this was related to specific symptoms. There were similar correlates of being supportive of routine alcohol screening and brief intervention delivery in both countries. Support was lower in both countries amongst moderate and risky drinkers, and among single adults or those on parental leave, but higher amongst older individuals. Having had an alcohol conversation in healthcare increased the level of support for alcohol prevention in routine healthcare among risky drinkers. There is a high level of support for preventative alcohol conversations in routine healthcare in Norway and Sweden, although there was a lower proportion of respondents who were positive to alcohol prevention in routine healthcare in Norway compared to Sweden. Experiencing alcohol conversation may positively affect risky drinkers’ attitudes towards and support for alcohol prevention. Thus, more frequent alcohol conversations in routine healthcare may also result in increased level of support for alcohol prevention among risky drinkers.
- Open Access
- 4 March 2020
- Published by Springer Nature in BMC Public Health
- Vol. 20 (1) , 1-11
Conversations about alcohol in healthcare – cross-sectional surveys in the Netherlands and Sweden
Background: This study evaluated and compared the extent, duration, contents, experiences and effects of alcohol conversations in healthcare in the Netherlands and Sweden in 2017. Methods: Survey data in the Netherlands and Sweden were collected through an online web panel. Subjects were 2996 participants (response rate: 50.8%) in Sweden and 2173 (response rate: 82.2%) in the Netherlands. Data was collected on socio-demographics, alcohol consumption, healthcare visits in the past 12 months, number of alcohol conversations, and characteristics of alcohol conversations (duration, contents, experience, effects). Results: Results showed that Swedish respondents were more likely to have had alcohol conversations (OR = 1.99; 95%CI = 1.64–2.41; p = < 0.001) compared to Dutch respondents. In Sweden, alcohol conversations were more often perceived as routine (p = < 0.001), were longer (p = < 0.001), and more often contained verbal information about alcohol’s health effects (p = 0.007) or written information (p = 0.001) than in the Netherlands. In Sweden, 40+ year-olds were less likely to report a positive effect compared to the youngest respondents. In the Netherlands, men, sick-listed respondents, and risky drinkers, and in Sweden those that reported “other” occupational status such as parental leave, were more likely to have had alcohol conversations. Conclusions: The results suggest that alcohol conversations are more common in healthcare practice in Sweden than in the Netherlands. However, positive effects of alcohol conversations were less likely to be reported among older respondents in Sweden. Our results indicate that alcohol preventative work should be improved in both countries, with more focus on risky drinkers and the content of the conversations in Sweden, and expanding alcohol screening in the Netherlands.
- 4 March 2020
- Published by Springer Nature in BMC Public Health
- Vol. 20 (1) , 1-11
Open AccessConversations about alcohol in healthcare – cross-sectional surveys in the Netherlands and Sweden
Background: This study evaluated and compared the extent, duration, contents, experiences and effects of alcohol conversations in healthcare in the Netherlands and Sweden in 2017. Methods: Survey data in the Netherlands and Sweden were collected through an online web panel. Subjects were 2996 participants (response rate: 50.8%) in Sweden and 2173 (response rate: 82.2%) in the Netherlands. Data was collected on socio-demographics, alcohol consumption, healthcare visits in the past 12 months, number of alcohol conversations, and characteristics of alcohol conversations (duration, contents, experience, effects). Results: Results showed that Swedish respondents were more likely to have had alcohol conversations (OR = 1.99; 95%CI = 1.64–2.41; p = < 0.001) compared to Dutch respondents. In Sweden, alcohol conversations were more often perceived as routine (p = < 0.001), were longer (p = < 0.001), and more often contained verbal information about alcohol’s health effects (p = 0.007) or written information (p = 0.001) than in the Netherlands. In Sweden, 40+ year-olds were less likely to report a positive effect compared to the youngest respondents. In the Netherlands, men, sick-listed respondents, and risky drinkers, and in Sweden those that reported “other” occupational status such as parental leave, were more likely to have had alcohol conversations. Conclusions: The results suggest that alcohol conversations are more common in healthcare practice in Sweden than in the Netherlands. However, positive effects of alcohol conversations were less likely to be reported among older respondents in Sweden. Our results indicate that alcohol preventative work should be improved in both countries, with more focus on risky drinkers and the content of the conversations in Sweden, and expanding alcohol screening in the Netherlands.
- 1 February 2020
- Published by Elsevier in Journal of Clinical Epidemiology
- Vol. 118, 55-59
Enrolment-latency in randomized behavior change trials: individual participant data meta-analysis showed association with attrition but not effect-size
- 1 February 2020
- Published by Elsevier in Journal of Clinical Epidemiology
- Vol. 118, 55-59
Enrolment-latency in randomized behavior change trials: individual participant data meta-analysis showed association with attrition but not effect-size
- 16 April 2019
- Published by Oxford University Press (OUP) in European Journal of Public Health
- Vol. 29 (4) , 748-753
Addressing alcohol in routine healthcare in Sweden—population-based surveys in 2010 and 2017
Background: The aim of the study was to compare how alcohol was addressed in routine healthcare practice in Sweden in 2010 and 2017, following the 2011 implementation of national drinking guidelines. Methods: Population-based cross-sectional surveys were conducted in 2010 and in 2017. Subjects were 3200 respondents in 2010 (response rate 54%) and 3000 respondents in 2017 (response rate 51%) in Sweden. Both the 2010 and 2017 surveys collected data on: socio-demographics; alcohol consumption; healthcare visits in the past 12 months and characteristics of alcohol conversations in healthcare (duration, contents, experience and effects). Results: It was significantly more likely that respondents had a conversation about alcohol in healthcare in 2017 than in 2010 (OR = 1.49; 95% CI = 1.27–1.75; P<0.001). Conversations about alcohol in the healthcare were mostly short (<4 min), both in 2010 and 2017. The alcohol conversations in 2017 included less information about alcohol’s influence on health (P = 0.002) compared with 2010. The experience of the conversation about alcohol was perceived as less dramatic in 2017 than in 2010 (P = 0.038). Conclusions: The results suggest that conversations about alcohol were more embedded in routine healthcare practice in Sweden in 2017 than in 2010. This development has occurred since the 2011 publication of the national guidelines. Alcohol conversations targeted also specific groups of drinkers as recommended by the guidelines. However, our study design does not allow for conclusions about the relationship between the guidelines and the changes in healthcare practice.
- 16 April 2019
- Published by Oxford University Press (OUP) in European Journal of Public Health
- Vol. 29 (4) , 748-753
Addressing alcohol in routine healthcare in Sweden—population-based surveys in 2010 and 2017
Background: The aim of the study was to compare how alcohol was addressed in routine healthcare practice in Sweden in 2010 and 2017, following the 2011 implementation of national drinking guidelines. Methods: Population-based cross-sectional surveys were conducted in 2010 and in 2017. Subjects were 3200 respondents in 2010 (response rate 54%) and 3000 respondents in 2017 (response rate 51%) in Sweden. Both the 2010 and 2017 surveys collected data on: socio-demographics; alcohol consumption; healthcare visits in the past 12 months and characteristics of alcohol conversations in healthcare (duration, contents, experience and effects). Results: It was significantly more likely that respondents had a conversation about alcohol in healthcare in 2017 than in 2010 (OR = 1.49; 95% CI = 1.27–1.75; P<0.001). Conversations about alcohol in the healthcare were mostly short (<4 min), both in 2010 and 2017. The alcohol conversations in 2017 included less information about alcohol’s influence on health (P = 0.002) compared with 2010. The experience of the conversation about alcohol was perceived as less dramatic in 2017 than in 2010 (P = 0.038). Conclusions: The results suggest that conversations about alcohol were more embedded in routine healthcare practice in Sweden in 2017 than in 2010. This development has occurred since the 2011 publication of the national guidelines. Alcohol conversations targeted also specific groups of drinkers as recommended by the guidelines. However, our study design does not allow for conclusions about the relationship between the guidelines and the changes in healthcare practice.
- Open Access
- 25 June 2018
- Published by JMIR Publications Inc. in JMIR mHealth and uHealth
- Vol. 6 (6) , e146
Effectiveness of a Text Messaging–Based Intervention Targeting Alcohol Consumption Among University Students: Randomized Controlled Trial
Mobile and tablet apps, ubiquitous and pervasive computing, wearable computing and domotics for health.
- 25 June 2018
- Published by JMIR Publications Inc. in JMIR mHealth and uHealth
- Vol. 6 (6) , e146
Open AccessEffectiveness of a Text Messaging–Based Intervention Targeting Alcohol Consumption Among University Students: Randomized Controlled Trial
Mobile and tablet apps, ubiquitous and pervasive computing, wearable computing and domotics for health.
- Open Access
- 21 March 2018
- Published by Springer Nature in BMC Public Health
- Vol. 18 (1) , 391
Beliefs and attitudes about addressing alcohol consumption in health care: a population survey in England
Despite robust evidence for their effectiveness, it has proven difficult to translate alcohol prevention activities into routine health care practice. Previous research has identified numerous provider-level barriers affecting implementation, but these have been less extensively investigated in the wider population. We sought to: (1) investigate patients’ beliefs and attitudes to being asked about alcohol consumption in health care; and (2) identify the characteristics of those who are supportive of addressing alcohol consumption in health care. Cross-sectional household interviews conducted as part of the national Alcohol Toolkit Study in England between March and April 2017. Data were collected on age, gender, social grade, drinking category, and beliefs and attitudes to being asked about alcohol in routine health care. Unadjusted and multivariate-adjusted logistic regression models were performed to investigate associations between socio-demographic characteristics and drinking category with being “pro-routine” (i.e. ‘agree completely’ that alcohol consumption should be routinely addressed in health care) or “pro-personal” (i.e. ‘agree completely’ that alcohol is a personal matter and not something health care providers should ask about). Data were collected on 3499 participants, of whom 50% were “pro-routine” and 10% were “pro-personal”. Those in social grade C1, C2, D and E were significantly less likely than those in AB of being “pro-routine”. Women were less likely than men to be “pro-personal”, and those aged 35–44 or 65 years plus more likely to be “pro-personal” compared with participants aged 16–24. Respondents aged 65 plus were twice as likely as those aged 16–24 to agree completely that alcohol consumption is a personal matter and not something health care providers should ask about (OR 2.00, 95% CI 1.34–2.99). Most adults in England agree that health care providers should routinely ask about patients’ alcohol consumption. However, older adults and those in lower socio-economic groups are less supportive. Drinking status appears to have limited impact on whether people believe that alcohol is a personal matter and not something health care providers should ask about. Open Science Framework ( https://osf.io/xn2st/ ).
- 21 March 2018
- Published by Springer Nature in BMC Public Health
- Vol. 18 (1) , 391
Open AccessBeliefs and attitudes about addressing alcohol consumption in health care: a population survey in England
Despite robust evidence for their effectiveness, it has proven difficult to translate alcohol prevention activities into routine health care practice. Previous research has identified numerous provider-level barriers affecting implementation, but these have been less extensively investigated in the wider population. We sought to: (1) investigate patients’ beliefs and attitudes to being asked about alcohol consumption in health care; and (2) identify the characteristics of those who are supportive of addressing alcohol consumption in health care. Cross-sectional household interviews conducted as part of the national Alcohol Toolkit Study in England between March and April 2017. Data were collected on age, gender, social grade, drinking category, and beliefs and attitudes to being asked about alcohol in routine health care. Unadjusted and multivariate-adjusted logistic regression models were performed to investigate associations between socio-demographic characteristics and drinking category with being “pro-routine” (i.e. ‘agree completely’ that alcohol consumption should be routinely addressed in health care) or “pro-personal” (i.e. ‘agree completely’ that alcohol is a personal matter and not something health care providers should ask about). Data were collected on 3499 participants, of whom 50% were “pro-routine” and 10% were “pro-personal”. Those in social grade C1, C2, D and E were significantly less likely than those in AB of being “pro-routine”. Women were less likely than men to be “pro-personal”, and those aged 35–44 or 65 years plus more likely to be “pro-personal” compared with participants aged 16–24. Respondents aged 65 plus were twice as likely as those aged 16–24 to agree completely that alcohol consumption is a personal matter and not something health care providers should ask about (OR 2.00, 95% CI 1.34–2.99). Most adults in England agree that health care providers should routinely ask about patients’ alcohol consumption. However, older adults and those in lower socio-economic groups are less supportive. Drinking status appears to have limited impact on whether people believe that alcohol is a personal matter and not something health care providers should ask about. Open Science Framework ( https://osf.io/xn2st/ ).
- Open Access
- 13 December 2017
- Published by JMIR Publications Inc. in JMIR Preprints
Effectiveness of a Text Messaging Based Intervention Targeting Alcohol Consumption Among University Students: Randomized Controlled Trial (Preprint)
BACKGROUND Excessive drinking among university students is a global challenge, leading to significant health risks. However, heavy drinking among students is widely accepted and socially normalized. Mobile phone interventions have attempted to reach students who engage in excessive drinking. A growing number of studies suggest that text message–based interventions could potentially reach many students and, if effective, such an intervention might help reduce heavy drinking in the student community. OBJECTIVE The objective of this study was to test the effectiveness of a behavior change theory–based 6-week text message intervention among university students. METHODS This study was a two-arm, randomized controlled trial with an intervention group receiving a 6-week text message intervention and a control group that was referred to treatment as usual at the local student health care center. Outcome measures were collected at baseline and at 3 months after the initial invitation to participate in the intervention. The primary outcome was total weekly alcohol consumption. Secondary outcomes were frequency of heavy episodic drinking, highest estimated blood alcohol concentration, and number of negative consequences attributable to excessive drinking. RESULTS A total of 896 students were randomized to either the intervention or control group. The primary outcome analysis included 92.0% of the participants in the intervention group and 90.1% of the control group. At follow-up, total weekly alcohol consumption decreased in both groups, but no significant between-group difference was seen. Data on the secondary outcomes included 49.1% of the participants in the intervention group and 41.3% of the control group. No significant between-group difference was seen for any of the secondary outcomes. CONCLUSIONS The present study was under-powered, which could partly explain the lack of significance. However, the intervention, although theory-based, needs to be re-assessed and refined to better support the target group. Apart from establishing which content forms an effective intervention, the optimal length of an alcohol intervention targeting students also needs to be addressed in future studies. CLINICALTRIAL International Standard Randomised Controlled Trial Number ISRCTN95054707; http://www.isrctn.com/ISRCTN95054707 (Archived by WebCite at http://www.webcitation.org/70Ax4vXhd)
- 13 December 2017
- Published by JMIR Publications Inc. in JMIR Preprints
Open AccessEffectiveness of a Text Messaging Based Intervention Targeting Alcohol Consumption Among University Students: Randomized Controlled Trial (Preprint)
BACKGROUND Excessive drinking among university students is a global challenge, leading to significant health risks. However, heavy drinking among students is widely accepted and socially normalized. Mobile phone interventions have attempted to reach students who engage in excessive drinking. A growing number of studies suggest that text message–based interventions could potentially reach many students and, if effective, such an intervention might help reduce heavy drinking in the student community. OBJECTIVE The objective of this study was to test the effectiveness of a behavior change theory–based 6-week text message intervention among university students. METHODS This study was a two-arm, randomized controlled trial with an intervention group receiving a 6-week text message intervention and a control group that was referred to treatment as usual at the local student health care center. Outcome measures were collected at baseline and at 3 months after the initial invitation to participate in the intervention. The primary outcome was total weekly alcohol consumption. Secondary outcomes were frequency of heavy episodic drinking, highest estimated blood alcohol concentration, and number of negative consequences attributable to excessive drinking. RESULTS A total of 896 students were randomized to either the intervention or control group. The primary outcome analysis included 92.0% of the participants in the intervention group and 90.1% of the control group. At follow-up, total weekly alcohol consumption decreased in both groups, but no significant between-group difference was seen. Data on the secondary outcomes included 49.1% of the participants in the intervention group and 41.3% of the control group. No significant between-group difference was seen for any of the secondary outcomes. CONCLUSIONS The present study was under-powered, which could partly explain the lack of significance. However, the intervention, although theory-based, needs to be re-assessed and refined to better support the target group. Apart from establishing which content forms an effective intervention, the optimal length of an alcohol intervention targeting students also needs to be addressed in future studies. CLINICALTRIAL International Standard Randomised Controlled Trial Number ISRCTN95054707; http://www.isrctn.com/ISRCTN95054707 (Archived by WebCite at http://www.webcitation.org/70Ax4vXhd)