Abbas Washeel Salman

Several synthetic approaches, such as solvothermal, microwave-assisted, electrochemical, and mechanochemical techniques, are used in the creation of metal-organic frameworks (MOFs). The resulting MOFs can be tailored for particular purposes by utilizing the distinct benefits that each of these approaches offers in terms of managing their size, shape, and functional qualities. The most recent developments in MOF synthesis are examined in this study along with how they are being used in optoelectronic devices such as photodiodes, solar cells, and light-emitting diodes (LEDs). MOFs are potential candidates for these applications because of their special qualities, which include their capacity to host light-emitting guest molecules, promote charge transport, and improve light absorption. MOFs effectively house luminescent centers in LEDs, improving brightness and color purity. MOFs improve charge separation and light collecting efficiency in solar cells. The customizable band gaps of MOFs, which may be designed to maximize their performance in photodetection, are advantageous to photodiodes. Advances in MOFs could revolutionize future optoelectronics. Finally, MOFs are based on the ongoing development of advanced synthetic methods that allow for the fabrication of LEDs, solar cells and photodetectors at higher levels of technological innovation and application. Additionally, MOFs in photodetectors, are thought to be active material and their special capacity to interact at various wavelengths may pave the way for more sensitive and adaptable application-specific sensors in a range of areas, including high-speed communication technologies and environmental monitoring.

Schiff bases have proven to be beneficial in medicine and have interesting complexation capabilities with transition metals. The +4, +5, and +6 oxidation states of schiff base metal complexes have been the subject of recent review, which have highlighted their notable cytotoxic effects against various colon cancer cell lines (HT-29, HCT-116, SW-480, Coco-2, CT-26, LT-174, LoVo). Extensive research has focused on schiff base metal complexes in the +4 and +6 oxidation states, exhibiting distinct geometries and significant thermodynamic stability. These studies provide IC₅₀ values for these complexes in colon cancer cell lines along with comprehensive structural representations that shed light on how different substituents affect cytotoxicity. When compared to schiff base ligands alone, metal complexes of schiff bases have been shown to significantly reduce colon cancer cell invasion and proliferation. The studied literature emphasizes schiff base metal complexe’s potential in biological applications and suggests that more study may be necessary to fully comprehend their biology. To enable more sophisticated multidisciplinary study in this field, future investigations should focus on synthesizing novel complexes with enhanced bioavailability, solubility, and low toxicity.

The present review deeply delves the major methods for the synthesis of organotellurium compounds along with their biological significance. Elaboration of various precursors (ligands) including Schiff bases, naphthoquinones, amino acids, β-hydroxy alkylated compounds, β-phenyltelluro alcohols, β-aryltelluro amines, β-aryl-chalcogenium azides, chalcogenobiotin, benzenesulfonamide, carbonic anhydrase, and Sulpha compounds has been briefly described. Furthermore, the article investigates their possible biological uses, specifically as antioxidant and anticancer agents while comparing their effectiveness with their respective ligands and with the standard medications in terms IC₅₀ values. All types of details are haunted to make the information a priceless resource for researchers who wish to probe deeper into and examine the diverse roles that organotellurium complexes play in biological settings.

Breast cancer cells have long been inhibited by polypyridine Ru(II) complexes, which are excellent antitumor agents. Due to their multi-targeting properties, this class of ruthenium complexes has received increasing attention as anticancer drug candidates approach to various cellular targets. The aim of this review is to give information about the ligands that were carefully chosen for ruthenium complexes. There has been a great deal of interest in using ruthenium-based complexes to treat breast cancer. Several species have shown potential as treatment candidates. However, further research is needed to determine how these agents affect the metastatic potential of breast cancer cells. The mechanism of action of Ru-based anticancer candidates NAMI-A and KP1019 during phase I clinical trials has been discussed. This article explains hormone-positive breast cancer and triple-negative breast-cancer treatment by using Ru complexes. Although platinum (Pt-based) anticancer medication is widely used in cancer treatment, a minor improvement has been seen and that is Platinum replaced with Ruthenium for its anticancer properties. We have also highlighted the best effective ruthenium-based complexes in treating T.N.B.C. (triple-negative breast cancer) here in this collection.

In this current research work, hydrogel composite polymer of sodium alginate-g-(polyacrylicacid-co-Sodium4-vinylbenzenesulfonate)/zinic oxide hydrogel (SA-g-(PAAc-co-VBS)/ZnO has been synthesized to be an efficient adsorbent for cationic dye namely crystal violet (CV). The physicochemical properties of the synthesized compound were identified via several characterization techniques such as Fourier transform infrared (FTIR), Field emission scanning electron microscope (FE-SEM), Thermo gravimetric analysis (TGA), X-ray diffraction (XRD), and Transmission electron microscopes (TEM). The adsorption kinetics and equilibrium isotherm of (SA-g-(PAAC-co-VBS)/ZnO towards CV removal were best fitted the pseudo-first-order and Freundlich isotherm models respectively (Qe =956.56 mg/g ) at optimum condition temperatures 30 ^oC, Conc.= 200 mg. L^-1, pH= 6.6, and weight of surface 0.04 g/100 ml. Recyclability and Desorption studies indicated the best recycling performance at 3 cycles of using (SA-g-(PAAC-co-VBS)/ZnO), with a significant efficiency >80%. Depend on the results, the synthesized SA-g-(PAAc-co-VBS)/ZnO can be applied as a promising, eco-friendly, cost-effective, and efficient adsorbent for cationic dye removal.

Pd(II) and trinuclear Ag(I) bis-N-heterocyclic carbene complexes: Synthesis, structural and in vitro anticancer activity

N‐Heterocyclic carbenes (NHCs) complexed with silver represent new, broad‐spectrum antimicrobial and anticancer agents, normally with low toxicity profiles, and they provide a range of versatile structures for targeted biological applications. Most of these complexes have shown higher cytotoxicity than cisplatin, a potent anticancer drug. This study reviews the design, synthesis, structural characterization, and biological applications of silver complexes derived from both functionalized and nonfunctionalized NHC ligands. Specifically, silver complexes of functionalized and nonfunctionalized imidazole‐ and benzimidazole‐based NHC systems employed in antimicrobial and anticancer applications are reviewed. Advancements achieved in the use of silver(I)–NHC complexes of miscellaneous azolium ligands, such as 1,2,4‐triazole and the heterocycle‐fused imidazolium derivative xanthene are also reviewed. Encapsulation of a series of silver–NHC complexes in a polymer‐based carrier material represents a promising method for the targeted delivery of silver ions to the infected sites. The advances achieved in this particular area are systematically reviewed in this paper. In general, these preliminary achievements reveal the potential of silver(I)–NHC complexes as efficient antimicrobial and anticancer candidates.