Yousef Veisani

Background and Aims: Intentional poisoning is a major public health challenge requiring rapid emergency intervention. This study aimed to identify demographic, psychiatric, and toxicological factors associated with intentional poisoning among patients presenting to a hospital emergency department. Methods: We conducted a retrospective cross‐sectional analysis of 658 poisoning cases recorded in a hospital emergency department poisoning registry in Ilam, Iran (March 2022–March 2023), with linked medical‐record data reviewed after the index encounter. The primary outcome was a final binary classification of intentional versus unintentional poisoning. Categorical associations were examined using Pearson chi‐square tests or Fisher exact tests as appropriate. A multivariable logistic regression model included five prespecified clinical/psychiatric variables and estimated adjusted odds ratios (aORs) with 95% confidence intervals (CIs). Analyses used Stata version 11.0 ( α = 0.05, two‐sided). Results: Of 658 patients, 367 (55.8%) were classified as intentional poisoning and 291 (44.2%) as unintentional. Intentional poisoning was more frequent among women than men (194/279, 69.5% vs. 173/379, 45.6%; p < 0.001) and among urban than rural residents (295/476, 62.0% vs. 72/182, 39.6%; p < 0.001). In the multivariable clinical model, previous suicide attempt showed the strongest association with intentional poisoning (aOR 4.69, 95% CI 2.55–8.61, p < 0.001), and psychiatric disorder history remained associated (aOR 1.78, 95% CI 1.02–3.12, p = 0.043); current psychiatric disorder did not remain independently associated after mutual adjustment (aOR 0.91, 95% CI 0.59–1.40, p = 0.669). Among specific agents, high intentional‐use proportions were observed for aluminum phosphide (17/18, 94.4%), antibiotics (13/15, 86.7%), and acetaminophen (35/43, 81.4%). Conclusions: Intentional poisoning was associated with distinct demographic patterns and psychiatric vulnerability, particularly a history of previous suicide attempts. These findings support systematic mental health assessment in emergency poisoning care and prevention strategies focused on patients with established self‐harm history and access to highly lethal agents.

Introduction: Breast cancer (BC) is the most common malignancy among women worldwide. Thus, this retrospective cohort study aimed to identify prognostic factors for BC-specific survival using parametric accelerated failure time models. Methods: Data were collected from 820 female patients diagnosed between 2014 and 2020 at Shahid Mostafa Khomeini Hospital in Ilam, Iran, with follow-ups through 2023. Survival time was defined from diagnosis to BC death or censoring. The Kaplan-Meier method, along with log-rank tests, was applied in the model. Results: Among 798 patients, 72 BC deaths occurred (9.0%). The goodness of fit in the log-normal model was evaluated using the Akaike Information Criterion (AIC=574.2) and the Bayesian Information Criterion (BIC=607.0). Moreover, histological type was the only significant independent predictor of survival. Compared with infiltrating ductal carcinoma, lobular carcinoma was associated with shorter survival (time ratio=0.613; 95% confidence interval: 0.401–0.939; P=0.024). Nonetheless, age, tumor topography, diagnostic method, and tumor grade were not statistically significant predictors. Conclusion: Histological type is a key prognostic factor for breast cancer survival, with non-ductal tumors indicating poorer outcomes. The log-normal model provides the best statistical fit for this analysis.

Background and Aims: Aggression and impulsiveness are personality traits linked to adolescent mental health and suicidal tendencies. Although their associations with suicidality have been reported, evidence on their independent effects among Iranian adolescents, especially in high‐risk regions, is limited. This study examined the relationships between aggression, impulsiveness, and suicidal tendencies among adolescents in a region of Iran. Methods: This descriptive‐analytic cross‐sectional study was conducted on 200 male and female secondary school students selected through multistage random sampling from four high schools. Data were collected using the Multi‐Attitude Suicide Tendency questionnaire, Buss–Perry Aggression Questionnaire, Impulsiveness Scale, and a demographic checklist. Data were analyzed using independent t‐tests, Pearson correlation, one‐way ANOVA, and multiple linear regression in SPSS version 23. Results: Male adolescents reported significantly higher aggression scores than females ( p = 0.03), while impulsiveness did not differ by gender ( p > 0.05). Aggression differed significantly across academic grades ( p = 0.02). Aggression showed a strong positive correlation with suicidal tendencies ( r = 0.61, p < 0.001), whereas impulsiveness demonstrated a weak correlation ( r = 0.18, p = 0.01). In regression analysis, aggression was a significant predictor of suicidal tendencies ( β = 0.61, p < 0.001), explaining 36% of the variance (R² = 0.36), while impulsiveness was not a significant predictor. Academic performance was significantly associated with aggression and impulsiveness, whereas parental education and occupation were not. Conclusion: Aggression is the main independent predictor of suicidal tendencies among adolescents, particularly males, while impulsiveness has a limited role. Early identification of aggressive behaviors and school‐based prevention programs are therefore essential in high‐risk regions.

Background: Despite receiving training on caring for burn wounds in the undergraduate nursing program, nursing students do not acquire enough knowledge and skills in wound dressing and debridement. This research was carried out to determine the effect of a training package on the nursing interns’ knowledge and executive functions regarding the ...

Background: Suicide is a complicated multifactorial phenomenon. Researchers have attempted to identify the reasons for suicide in different communities. The present study aimed to identify and scrutinize the risk factors for suicide among hospitalized patients. Methods: This qualitative grounded theory study was conducted using in-depth interviews with 53 hospitalized patients in Mostafa Hospital in Ilam, Iran in 2021. Semi-open questions were asked by a psychologist. The interviews continued until reaching the saturation point and achieving the specific objectives of the study. Finally, coding was performed using the grounded theory method. Results: A history of suicide attempts was reported by almost two-thirds of the individuals. The results of the primary coding of the items showed that the most important categories paving the path for committing suicide were social, financial, and family factors. Conclusion: According to the results of the present study, the most important causal conditions contributing to suicide attempts were psychological factors, addiction and its related problems, divorce and its related problems, and love failure.

Little information exists on the association between comorbidities of mental disorders and suicidal ideation in developing countries. The current study examined the relationship between the presence of comorbid mental disorders and suicidal ideation in the adult population. This cross-sectional study was conducted using the cluster random sampling method in 3 steps. Data were collected from a household assets survey and the self-administered 28-item General Health Questionnaire as first step in screening, and the Persian version of the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition - Text Revision was used in the second stage to determine the prevalence of mental disorders. Bivariate and multivariate analysis were used to investigate the associations between mental disorders and suicidal ideation. Of the 763 participants, 199 (26.1%) had 1 or more mental disorder. Forty-two (71.4%) subjects with comorbidities had a history of suicidal ideation, whereas 59 (7.7%) of all participants had a history of suicidal ideation. We found that major depressive disorder and obsessive-compulsive disorder were the most predictive of suicidal ideation in both sexes. The odds ratio for suicidal ideation associated with having 3 comorbid disorders was 2.70 (95% confidence interval [CI], 1.40 to 14.12) in males and 3.06 (95% CI, 1.25 to 15.22) in females. Consistent with pervious data, our results confirmed that mental disorders and comorbidities of mental disorders were important predictors of suicidal ideation. Our findings are very useful for applied intervention programs to reduce the suicide rate in regions in which it is high.

Context: Resent reviews have shown that about 18% of all child cancers are leukemia. Track of the survival rate can help researchers improve quality of life of patients through improving screening or discovery of better treatments. Objectives: This review aimed at estimating the 5-year survival rates and associated factors of childhood leukemia in Iran. Data Sources: We carried out a systematic review through search of relevant studies published in English (PubMed, Scopus, Google scholar, and ISI) and Persian databases (Magiran, Medlib, SID, and Iran Medex). Study Selection: The study included all epidemiologic studies that estimated survival rate in children with leukemia in Iran during years 2002 to 2015, and a standardized manner was used for extraction of information. Data Extraction: The entire text or summary of all searched articles was extracted and then, related articles were selected, and irrelevant ones were excluded. Fixed and random effects models were calculated by the STATA using standard meta-analysis methods. Heterogeneity was assessed by I² statistics. Results: The overall 5-year survival rate in patients with childhood leukemia in Iran was 0.65 (95% CI, 0.62 to 0.67, 10 studies), in the acute lymphoblastic leukemia (ALL) subtype was 71.0% (95% CI: 68.0 to 74.0), and in the acute myeloid leukemia (AML) subtype was 46.0%. Results of the meta analysis showed significant poor survival with relapse (heart rate (HR) 1.59, 95% confidence interval (CI) 1.27 to 1.98) and white blood count (WBC) counts ≥ 50,000 (HR 2.92, 95% CI 1.23 to 4.60). Conclusions: The results showed that 5-year survival rates in patients with AML were lower than patients with ALL. The results of this meta analysis strongly support the need for future research, action, and guidance for clinicians to improve health-related quality of life and outcomes for children with leukemia. Keywords: Leukemia; Acute Myeloid Leukemia; Acute Lymphocytic Leukemia; Survival Rate; Meta-Analysis