Yoon Jung Do

Feline health screening in South Korea lacks local disease priorities. We developed a model combining diagnostic proportions from 39,016 diagnosis entries with disease importance and treatment/management efficacy ratings from 39 veterinarians. Two scoring versions used different orders of multiplication and decile conversion across four life stages: kitten, young adult, mature adult, and senior. Eligibility required a stage-specific diagnostic proportion of at least half the overall proportion for that disease and at least 0.3% of diagnoses in that stage. The versions produced similar top-10 lists. Stomatitis was selected for all four life stages; stomatitis and six additional diseases—chronic kidney disease, urolithiasis, systemic hypertension, pancreatitis, diabetes mellitus, and periodontal disease—were selected for all three adult stages. Infectious diseases featured prominently in kittens, whereas chronic and metabolic diseases became prominent in older cats. Hyperthyroidism was selected only in seniors, and neoplasia remained below the top 10, reflecting its low efficacy score. Scoring prioritized severe chronic or life-threatening conditions more highly than diagnostic proportions alone. Diagnostic proportions describe recorded diagnoses rather than individual-cat population prevalence. These candidate lists require validation and evaluation of screening tests, clinical benefits, cost, accessibility, and patient stress before guidelines can be established.

To address persistent challenges in molecular detection—particularly signal variability, low analyte abundance, and poor spectral reproducibility—a portable bead-stacked nanosieve platform was engineered to enable robust on-chip Raman signal amplification using silver nanocubes (AgNCs) functionalized with Raman-active thiolated ligands. The microdevice integrates deformable elastomeric channels with magnetic bead stacking to immobilize and concentrate AgNCs within confined nanoscopic junctions, thereby generating densely packed plasmonic hot spot architectures that markedly enhance surface-enhanced Raman scattering efficiency. Time-resolved measurements revealed substantial increases in the Raman intensity for both 4-mercaptobenzoic acid (4-MBA) and 4-aminothiophenol (4-ATP), outperforming corresponding off-chip assays and maintaining stable enhancement factors over a 4 h operational window. Furthermore, the platform successfully demonstrated multiplexed sensing capability: mixed-analyte experiments containing 4-MBA, 4-ATP, and cysteamine produced clearly distinguishable spectral fingerprints, even under serial dilution and dynamically pulsed sample delivery. These results establish the bead-stacked nanosieve as a versatile and scalable diagnostic architecture capable of achieving high sensitivity and spectral fidelity under continuous-flow conditions.

Han Gyu Lee, Ara Cho, Young-Hun Jung, Yoon Jung Do, Eun-Young Bok, Are Sun You, Seogjin Kang. Korean J. Vet. Serv. 2026;49:103-10. https://doi.org/10.7853/kjvs.2026.49.1.103

Changyong Choe, Hyunkyoung Lee, Sankar Kathannan, Seungmin Ha, Jongho Kim, Mi-Hye Hwang, Gyu-Tae Jeon, Young-Hun Jung, Are-Sun You, Eun-Young Bok, Yoon Jung Do, Ara Cho, Han Gyu Lee, Bok-Kyung Ku, Seogjin Kang. Korean J. Vet. Serv. 2026;49:119-26. https://doi.org/10.7853/kjvs.2026.49.1.119

Park JY, et al. J Vet Sci. 2025 Dec;27:e5. https://doi.org/10.4142/jvs.25144

Changyong Choe, Han-Kyoung Lee, Ara Cho, Jae-Hee Roh, Sang-Ik Oh, Kyoung-Min So, Young-Hun Jung, Yoon Jung Do, Sankar Kathannan. Korean J. Vet. Serv. 2025;48:285-92. https://doi.org/10.7853/kjvs.2025.48.4.285

Changyong Choe, Hyunkyoung Lee, Sankar Kathannan, Seungmin Ha, Jongho Kim, Mi-Hye Hwang, Gyu-Tae Jeon, Young-Hun Jung, Are-Sun You, Eun-Young Bok, Yoon Jung Do, Ara Cho, Han Gyu Lee, Bok-Kyung Ku, Seogjin Kang. Korean J. Vet. Serv. 2025;48:269-76. https://doi.org/10.7853/kjvs.2025.48.3.269