Pingjian Yu
Research Subjects
Research Interests
Pingjian Yu has a total of 1 co-authors. Here are the top co-authors by number of shared publications:
- Wei Lin
Translational Genomics Research Institute, Molecular Medicine Division, Phoenix, AZ, USA
1 shared publication
Latest Publications
- Open Access
- 1 February 2016
- Published by Oxford University Press (OUP) in Genomics, Proteomics & Bioinformatics
- Vol. 14 (1) , 21-30
Single-Cell Transcriptome Study as Big Data
The rapid growth of single-cell RNA-seq studies (scRNA-seq) demands efficient data storage, processing, and analysis. Big-data technology provides a framework that facilitates the comprehensive discovery of biological signals from inter-institutional scRNA-seq datasets. The strategies to solve the stochastic and heterogeneous single-cell transcriptome signal are discussed in this article. After extensively reviewing the available big-data applications of next-generation sequencing (NGS)-based studies, we propose a workflow that accounts for the unique characteristics of scRNA-seq data and primary objectives of single-cell studies.
- 1 February 2016
- Published by Oxford University Press (OUP) in Genomics, Proteomics & Bioinformatics
- Vol. 14 (1) , 21-30
Open AccessSingle-Cell Transcriptome Study as Big Data
The rapid growth of single-cell RNA-seq studies (scRNA-seq) demands efficient data storage, processing, and analysis. Big-data technology provides a framework that facilitates the comprehensive discovery of biological signals from inter-institutional scRNA-seq datasets. The strategies to solve the stochastic and heterogeneous single-cell transcriptome signal are discussed in this article. After extensively reviewing the available big-data applications of next-generation sequencing (NGS)-based studies, we propose a workflow that accounts for the unique characteristics of scRNA-seq data and primary objectives of single-cell studies.