Antonello Nicolini

Article: Non-invasive ventilation support during feeding tube placement in amyotrophic lateral sclerosis patients with moderate to severe ventilatory impairment: an update - Panminerva Medica 2026 March;68(1):10-8 - Minerva Medica - Journals

Article: Effectiveness of a new “focused pulse” high-frequency chest wall oscillation in patients with moderate to severe COPD - Minerva Medica 2024 Jan 23 - Minerva Medica - Journals

Article: High-intensity non-invasive ventilation: a brief review and update - Minerva Respiratory Medicine 2023 December;62(4):177-82 - Minerva Medica - Journals

Article: Gender differences in obesity hypoventilation syndrome: a concise narrative review - Minerva Medica 2022 Oct 31 - Minerva Medica - Journals

Article: Prevalence of airflow obstruction in an apparently healthy population sample: a preliminary Italian study - Panminerva Medica 2023 Apr 06 - Minerva Medica - Journals

Non-invasive ventilatory support (NVS) is a technique used to reduce respiratory work in neuromuscular diseases, preventing the progression of respiratory failure. NVS is usually administered via a nasal or an oronasal mask, causing discomfort, especially in patients ventilated for more than 16 h/day. Intermittent abdominal pressure ventilation (IAPV) differs completely from conventional NVS and consists of a portable ventilator and a corset with Velcro closures as the interface. In our study, the practicability and efficacy of IAPV were studied in three Italian centers monitoring 28 neuromuscular patients using IAPV who were then retrospectively analyzed. The primary outcomes were an improvement in hypoxemia and the normalization of hypercapnia, and the secondary outcome was an improvement in quality of life. Data were collected at baseline (T0) and after two hours of ventilation (T1), with follow-ups at three months (T2) and six months (T3). Statistical significance was found for PaCO₂ over time (F (2.42) = 7.63, p = 0.001) and PaO₂ (W = 0.539, p = 0.033). The time of NVS usage also significantly affected the quality of life (F (2.14) = 6.90, p = 0.010), as seen when comparing T0 and T3. As an alternative ventilation method, IAPV is still relevant today and could become a key part of daytime support, especially for patients who do not tolerate standard daytime NVS with an oral interface.

Article: Acute respiratory failure due to cutis laxa pulmonary emphysema treated with high-flow nasal cannula - Minerva Respiratory Medicine 2023 March;62(1):50-3 - Minerva Medica - Journals

Article: Predictive factors of noninvasive ventilation failure - Minerva Respiratory Medicine 2022 December;61(4):181-8 - Minerva Medica - Journals

Article: Comparison of two mechanical insufflation-exsufflation devices in patients with amyotrophic lateral sclerosis: a preliminary study - Panminerva Medica 2021 Mar 09 - Minerva Medica - Journals

Article: Differences between sexes concerning COVID-19-related pneumonia - Panminerva Medica 2022 December;64(4):517-24 - Minerva Medica - Journals