Golla Madhu

Gallbladder diseases present a significant clinical challenge due to their diverse manifestations and the difficulty of accurate interpretation in ultrasound imaging. Manual assessment of gallbladder ultrasound images is time consuming, operator dependent and may delay clinical decision making, motivating the development of automated diagnosis approaches. In this study, we propose a customized capsule network architecture, termed GBCapsNet, for multi-class disease classification using ultrasound images. The model incorporates a modified routing mechanism designed to improve feature representation and class discrimination. The proposed architecture was evaluated across multiple training-test splits, demonstrating high classification performance under image level splits (maximum accuracy of 99.91% and AUC of 1.0). However due to the use of image level splitting rather than patient level separation, these results should be interpreted with caution. Further validation using patient level splits and external datasets is required to establish clinical generalizability. To assess the reliability of predicted probabilities, post training calibration was performed using temperature scaling, resulting in reduced Expected Calibration Error (ECE). These results indicate improved alignment between predicted confidence scores and observed outcomes, although broader validation is required to establish generalizability. To the best of our knowledge, this work represents one of the early investigations into the applications of capsule networks for automated gallbladder disease diagnosis from ultrasound images, Overall, the findings suggest that capsule-based architectures are a promising direction for improving automated interpretation of gallbladder ultrasound data, warranting further validation on larger and more diverse clinical datasets.

Background/Objectives: Breast cancer remains one of the biggest health challenges for women worldwide, and early detection can be truly lifesaving. Although ultrasound imaging is commonly used to detect tumors, the images are not always of sufficient quality, and, thus, traditional U-Net models often miss the finer details needed for accurate detection. This outcome can result in lower accuracy, making early and precise diagnosis more difficult. Methods: This study presents an enhanced U-Net model integrated with a Capsule Network (called UCapsNet) to overcome the limitations of conventional techniques. Our approach improves segmentation by leveraging higher filter counts and skip connections, while the capsule network enhances classification by preserving spatial hierarchies through dynamic routing. The proposed UCapsNet model operates in two stages: first, it segments tumor regions using an enhanced U-Net, followed by a classification of the segmented images with the capsule network. Results: We have tested our model against well-known pre-trained models, including VGG-19, DenseNet, MobileNet, ResNet-50, and Xception. By properly addressing the limitations found in previous studies and using a capsule network trained on the Breast Ultrasound Image (BUSI) dataset, our model resulted in top-achieving impressive precision, recall, and accuracy rates of 98.12%, 99.52%, and 99.22%, respectively. Conclusions: By combining the U-Net’s powerful segmentation capabilities with the capsule network’s high classification accuracy, UCapsNet boosts diagnostic precision and addresses key weaknesses in existing methods. The findings demonstrate that the proposed model is not only more effective in detecting tumors but also more reliable for practical applications in clinical settings.

Global livelihoods are impacted by the novel coronavirus (COVID-19) disease, which mostly affects the respiratory system and spreads via airborne transmission. The disease has spread to almost every nation and is still widespread worldwide. Early and reliable diagnosis is essential to prevent the development of this highly risky disease. The computer-aided diagnostic model facilitates medical practitioners in obtaining a quick and accurate diagnosis. To address these limitations, this study develops an optimized Xception convolutional neural network, called "XCovNet," for recognizing COVID-19 from point-of-care ultrasound (POCUS) images. This model employs a stack of modules, each of which has a slew of feature extractors that enable it to learn richer representations with fewer parameters. The model identifies the presence of COVID-19 by classifying POCUS images containing Coronavirus samples, viral pneumonia samples, and healthy ultrasound images. We compare and evaluate the proposed network with state-of-the-art (SOTA) deep learning models such as VGG, DenseNet, Inception-V3, ResNet, and Xception Networks. By using the XCovNet model, the previous study's problems are cautiously addressed and overhauled by achieving 99.76% accuracy, 99.89% specificity, 99.87% sensitivity, and 99.75% F1-score. To understand the underlying behavior of the proposed network, different tests are performed on different shuffle patterns. Thus, the proposed "XCovNet" can, in regions where test kits are limited, be used to help radiologists detect COVID-19 patients through ultrasound images in the current COVID-19 situation.

Malaria is an acute fever sickness caused by the Plasmodium parasite and spread by infected Anopheles female mosquitoes. It causes catastrophic illness if left untreated for an extended period, and delaying exact treatment might result in the development of further complications. The most prevalent method now available for detecting malaria is the microscope. Under a microscope, blood smears are typically examined for malaria diagnosis. Despite its advantages, this method is time-consuming, subjective, and requires highly skilled personnel. Therefore, an automated malaria diagnosis system is imperative for ensuring accurate and efficient treatment. This research develops an innovative approach utilizing an urgent, inception-based capsule network to distinguish parasitized and uninfected cells from microscopic images. This diagnostic model incorporates neural networks based on Inception and Imperative Capsule networks. The inception block extracts rich characteristics from images of malaria cells using a pre-trained model, such as Inception V3, which facilitates efficient representation learning. Subsequently, the dynamic imperative capsule neural network detects malaria parasites in microscopic images by classifying them into parasitized and healthy cells, enabling the detection of malaria parasites. The experiment results demonstrate a significant improvement in malaria parasite recognition. Compared to traditional manual microscopy, the proposed system is more accurate and faster. Finally, this study demonstrates the need to provide robust and efficient diagnostic solutions by leveraging state-of-the-art technologies to combat malaria.

In recent years, various deep neural networks with different learning paradigms have been widely employed in various applications, including medical diagnosis, image analysis, self-driving vehicles and others. The activation functions employed in deep neural networks have a huge impact on the training model and the reliability of the model. The Rectified Linear Unit (ReLU) has recently emerged as the most popular and extensively utilized activation function. ReLU has some flaws, such as the fact that it is only active when the units are positive during back-propagation and zero otherwise. This causes neurons to die (dying ReLU) and a shift in bias. However, unlike ReLU activation functions, Swish activation functions do not remain stable or move in a single direction. This research proposes a new activation function named NIPUNA for deep neural networks. We test this activation by training on customized convolutional neural networks (CCNN). On benchmark datasets (Fashion MNIST images of clothes, MNIST dataset of handwritten digits), the contributions are examined and compared to various activation functions. The proposed activation function can outperform traditional activation functions.

With continuous advancements in Internet technology and the increased use of cryptographic techniques, the cloud has become the obvious choice for data sharing. Generally, the data are outsourced to cloud storage servers in encrypted form. Access control methods can be used on encrypted outsourced data to facilitate and regulate access. Multi-authority attribute-based encryption is a propitious technique to control who can access encrypted data in inter-domain applications such as sharing data between organizations, sharing data in healthcare, etc. The data owner may require the flexibility to share the data with known and unknown users. The known or closed-domain users may be internal employees of the organization, and unknown or open-domain users may be outside agencies, third-party users, etc. In the case of closed-domain users, the data owner becomes the key issuing authority, and in the case of open-domain users, various established attribute authorities perform the task of key issuance. Privacy preservation is also a crucial requirement in cloud-based data-sharing systems. This work proposes the SP-MAACS scheme, a secure and privacy-preserving multi-authority access control system for cloud-based healthcare data sharing. Both open and closed domain users are considered, and policy privacy is ensured by only disclosing the names of policy attributes. The values of the attributes are kept hidden. Characteristic comparison with similar existing schemes shows that our scheme simultaneously provides features such as multi-authority setting, expressive and flexible access policy structure, privacy preservation, and scalability. The performance analysis carried out by us shows that the decryption cost is reasonable enough. Furthermore, the scheme is demonstrated to be adaptively secure under the standard model.