Jasper Palmier-Claus

Background: People with severe mental illness (e.g. bipolar disorder, psychosis) experience poor oral health compared to the general population. They are more likely to have decayed, missing or filled teeth, and periodontal disease, which can affect quality of life and functioning. It can add to the burden of living with severe mental illness. Dentists can prevent and treat oral health problems. However, people with severe mental illness experience profound and multifaceted barriers to attendance, including practical issues, financial difficulties and dental anxiety. Unfortunately, existing dental interventions have not addressed these issues. They have not helped people with severe mental illness to attend the dentist. This project aimed to develop and evaluate a link work intervention, delivered by mental health support workers, to enable dental access in people with severe mental illness. The intervention attempted to help people to navigate dental systems and bridge the gap between services. There were four work packages: Work package 1 involved 4 co-production workshops with patients, staff, and carers (7, 6, 8 and 12 attendees, respectively). We used this information to co-develop and refine the link work intervention and associated training materials. This step ensured that the intervention was relevant and helpful to people with mental health difficulties. Work package 2 was a realist review to understand the contexts and resultant mechanisms by which link work interventions affect access to community healthcare services. A search of empirical and grey literature identified 31 reports. The analysis resulted in nine context, mechanism, and outcome configurations within three theory areas, providing useful information on how and why link work interventions might be helpful. Work package 3 was a feasibility randomised controlled trial of a link work intervention to support dental access in people with severe mental illness who had not attended a routine dental appointment in the past 3 years. Seventy-nine out of the target 84 participants were randomised to receiving either treatment as usual or treatment as usual plus the link work intervention. The majority of the feasibility criteria were met and there was high engagement with the intervention. Uptake of an optional dental examination was low at follow-up (12.7%; 95% CI: 7.0% to 21.8%). There were no serious adverse events attributable to the intervention or trial procedures. Overall, the findings supported progression to a full trial. Work package 4 was an embedded qualitative evaluation of the link work intervention and trial. Narrative-informed interviews were carried out with 18 participants in the trial (13 in the intervention arm, 5 in the treatment as usual arm) and 3 link workers. The qualitative data suggested high levels of interest and engagement from stakeholders, and need for dental intervention. The link work intervention offered practical and emotional support at different stages of access to address barriers to dental visiting at the individual, relational and organisational level. Overall, the project successfully developed and evaluated a link work intervention to enable dental access in people with severe mental illness. Limitations: The authors followed participants up after 9 months and the feasibility of longer-term retention is unknown. Future work: The next step is to explore the effectiveness and cost-effectiveness of the link work intervention through a full trial. Funding: This synopsis presents independent research funded by the National Institute for Health and Care Research (NIHR) Health and Social Care Delivery Research programme as award number NIHR132853.

Objectives: People with severe mental illness experience poor oral health, compared to the general population. They experience inequity in accessing dental services. This randomised controlled trial evaluated the acceptability and feasibility of a link work intervention to support people with severe mental illness to access a routine dental appointment.Methods: This was a feasibility randomised controlled trial across three sites with 1:1 allocation to Treatment as usual (TAU) or TAU plus a link work intervention (ISRCTN13650779). Participants were adults accessing mental health services who had not attended a routine dental appointment in the past 3 years. The intervention comprised up to six sessions with a link worker. Participants completed self‐report assessments and an optional dental examination at baseline and after nine months. Dental visiting data were obtained through self‐report and the NHS Business Services Authority (BSA).Results: One hundred and sixty‐one participants were referred into the trial, resulting in 79 out of the target 84 randomisations (94.0%) over 7 months. There were high levels of engagement with the intervention. Dental visiting data were available for 84.8% of participants (95% CI: 75.3%, 91.1%). Uptake of the optional dental examination within the research assessment battery was low (follow‐up: 12.7%; 95% CI: 7.0%, 21.8%). There were no serious adverse events attributable to the intervention or trial procedures. There were substantially higher rates of dental attendance after nine months in the link work intervention arm, compared to TAU, in both the self‐report (91.7% vs. 26.7%) and NHS BSA (55.3% vs. 12.1%) data. There was also a signal of improved self‐reported oral health‐related quality of life favouring the link work intervention arm.Conclusions: The trial procedures and link work intervention were found to be feasible, acceptable and safe. The intervention showed promise in terms of clinical outcomes. The effectiveness of the intervention requires evaluation in a larger trial.Trial Registration: NCT05545228

Background: Bipolar is a severe mental health condition affecting at least 2% of the global population, with clinical observations suggesting that individuals experiencing elevated mood states, such as mania or hypomania, may have an increased propensity for engaging in risk-taking behaviors, including hypersexuality. Hypersexuality has historically been stigmatized in society and in health care provision, which makes it more difficult for service users to talk about their behaviors. There is a need for greater understanding of hypersexuality to develop better evidence-based treatment, support, and training for health professionals. Objective: This study aimed to develop and assess effective methodologies for identifying posts on Reddit related to hypersexuality posted by people with a self-reported bipolar diagnosis. Using natural language processing techniques, this research presents a specialized dataset, the Talking About Bipolar on Reddit Corpus (TABoRC). We used various computational tools to filter and categorize posts that mentioned hypersexuality, forming the Hypersexuality in Bipolar Reddit Corpus (HiB-RC). This paper introduces a novel methodology for detecting hypersexuality-related conversations on Reddit and offers both methodological insights and preliminary findings, laying the groundwork for further research in this emerging field. Methods: A toolbox of computational linguistic methods was used to create the corpora and infer demographic variables for the Redditors in the dataset. The key psychological domains in the corpus were measured using Linguistic Inquiry and Word Count, and a topic model was built using BERTopic to identify salient language clusters. This paper also discusses ethical considerations associated with this type of analysis. Results: The TABoRC is a corpus of 6,679,485 posts from 5177 Redditors, and the HiB-RC is a corpus totaling 2146 posts from 816 Redditors. The results demonstrate that, between 2012 and 2021, there was a 91.65% average yearly increase in posts in the HiB-RC (SD 119.6%) compared to 48.14% in the TABoRC (SD 51.2%) and an 86.97% average yearly increase in users (SD 93.8%) compared to 27.17% in the TABoRC (SD 38.7%). These statistics suggest that there was an increase in posting activity related to hypersexuality that exceeded the increase in general Reddit use over the same period. Several key psychological domains were identified as significant in the HiB-RC (P<.001), including more negative tone, more discussion of sex, and less discussion of wellness compared to the TABoRC. Finally, BERTopic was used to identify 9 key topics from the dataset. Conclusions: Hypersexuality is an important symptom that is discussed by people with bipolar on Reddit and needs to be systematically recognized as a symptom of this illness. This research demonstrates the utility of a computational linguistic framework and offers a high-level overview of hypersexuality in bipolar, providing empirical evidence that paves the way for a deeper understanding of hypersexuality from a lived experience perspective.

Introduction: Inequity in access to healthcare in the United Kingdom can have a profound impact on people's ability to manage their health problems. Link work interventions attempt to overcome the socioeconomic and structural barriers that perpetuate health inequalities. Link workers are typically staff members without professional clinical qualifications who support patients to bridge the gap between services. However, little is currently known about how and why link work interventions might be effective. This realist review attempts to understand the contexts and resultant mechanisms by which link work interventions affect access to community healthcare services.Methods: The authors completed a systematic search of empirical literature in Embase, CINAHL, Medline, PsychInfo and SocIndex, as well as grey literature and CLUSTER searches. Context, mechanism and outcome (CMO) configurations were generated iteratively in consultation with an expert panel and grouped into theory areas.Results: Thirty‐one eligible manuscripts were identified, resulting in nine CMO configurations within three theory areas. These pertained to adequate time in time‐pressured systems; the importance of link workers being embedded across multiple systems; and emotional and practical support for link workers.Conclusion: Although link work interventions are increasingly utilised across community healthcare settings, the contexts in which they operate vary considerably, triggering a range of mechanisms. The findings suggest that careful matching of resources to patient need and complexity is important. It affords link workers the time to develop relationships with patients, embed themselves in local communities and referring teams, and develop knowledge of local challenges.Patient or Public Contribution: The team included people with lived experience of mental health conditions and a carer who were involved at all stages of the review.

Objectives: Higher education students experience elevated levels of suicidal ideation, but often face barriers in accessing support. The Mental Imagery for Suicidality in Students Trial (MISST; ISRCTN13621293; NCT05296538) tested the feasibility and acceptability of a six‐session imagery‐based approach called Broad‐Minded Affective Coping (BMAC). This qualitative evaluation explored the experiences of MISST participants and staff. Design: A qualitative study using one‐to‐one qualitative interviews with participants and staff recruited from MISST. Reflexive thematic analysis was used to explore trial participant and staff experiences to inform a future definitive trial. Methods: Student participants ( n = 16), research assistants ( n = 4) and the trial therapist ( n = 1) were interviewed and transcripts analysed using reflexive thematic analysis. Results: Four key themes were identified. The first theme highlights the value and challenges for students in talking about suicide. The ways in which communication and rapport can be built to facilitate this conversation are explored in theme 2. Theme 3 explains how working with the BMAC therapist increased participants’ awareness of their current mood, drew their attention to positive moments in their lives and helped them to actively recall these moments to interrupt negative cycles of rumination and suicidal ideation. The extent to which the BMAC is ‘fit for purpose’ is outlined in theme 4, generating specific recommendations for future intervention development. Conclusions: The BMAC offers a positive, time‐limited, structured intervention that is well suited to meet the needs of higher education students experiencing suicidal ideation. Further research is needed to test the effectiveness on mental health and suicide‐related outcomes.

Objectives: To provide detailed information on the codesign of a digital intervention to support parents with bipolar disorder (BD) who have young children. Each step of this process is reported, as well as a detailed description of the final version of the intervention in line with the TIDieR framework.Methods: Clinical experience and lived experience experts participated in online workshops, meetings, and remote feedback requests, informed by Integrated Knowledge Translation (IKT) principles. The IKT research group responded to each phase of recommendations from the knowledge users.Results: Five clinical experience experts and six lived experience experts engaged with the codesign process. Their recommendations for principles, content, look, and feel, and functionality of the digital intervention were structured over five iterative phases. This led to a final implemented design that was identified by the clinical and lived experience experts (referred to together as the knowledge users group) as genuinely reflecting their input.Conclusions: The IKT principles offer an accessible structure for engaging with clinical and lived experience experts throughout a codesign process, in this case for a digital intervention for parents with BD. The resulting intervention is described in detail for transparency to aid further evaluation and development and to help other teams planning codesign approaches to intervention development.