Depin Cao

Depin Cao

*This is an algorithmically generated author record based on publicly available information.

Current Organizations / Institutes

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Depin Cao has a total of 62 co-authors. Here are the top co-authors by number of shared publications:


Latest Publications

  • Open Access

    Nurse burnout: deep connections and solutions revealed by network analysis

    by Tianyi Bu, Chundi Peng, Jiangheng Liu, Xiaohui Qiu, Zhengxue Qiao, Jiawei Zhou, Siyuan Ke, Yuecui Kan, Xiaomeng Hu, Kexin Qiao, et al.

    Burnout is very important to nurses’ physical and mental health and career development. Current approaches to assessing nurse burnout tend to use a total score modeling paradigm to explore the impact of external factors on burnout. The purpose of this study is to delve into the item-level relationship between nurse burnout and its influencing factors at both the social and psychological levels using a network analysis approach. This study was conducted in June 2023 and 1,005 nurses from 4 hospitals out of 8 tertiary care hospitals in Harbin were selected to participate in this study using whole cluster sampling method. Measurements included a general demographic questionnaire, Trait coping styles questionnaire, Organizational commitment questionnaire, Work-family conflict scale, Transformational leadership questionnaire, and Maslach Burnout Inventory-General Survey. Our results suggest that “C1 Time-Based work interference with family” showed the strongest centrality and bridging in the overall network. This finding underscores its centrality to burnout. Other strongest bridge symptoms included “E2 Reduced personal accomplishment” and “A1 Positive coping styles” indicating their strongest connections to other clusters. Nurse administrators should be encouraged to pay more attention to nurses’ work situations and family distress, and to help nurses in a flexible way.


  • Open Access

    Relationship between psychological capital and depression in Chinese physicians: The mediating role of organizational commitment and coping style

    by Li Sun, Yuan Zhang, Jingyun He, Kexin Qiao, Ce Wang, Shuai Zhao, Jinxin Zhao, Xiaohui Qiu, Xiuxian Yang, Jiawei Zhou, et al.

    Background: It is well known that the medical profession is a high-risk practice, with intense work and complex situations. The physicians are prone to suffer from depression due to occupational stress under high workloads for long periods of time. Depression not only impairs physicians’ mental health, but also affects the quality of health services, so it is important to explore the factors and mechanisms affecting depression among physicians.Methods: In this cross-sectional study, 1,139 physicians from Heilongjiang Province were surveyed by cluster sampling procedures. The questionnaires included Psychological Capital Questionnaire, Chinese Employee Organizational Commitment Questionnaire, Trait Coping Style Questionnaire and Self-rating Depression Scale. Pearson correlation analysis and Bootstrap were used for statistical analysis.Results: This study found that 41.6% of physicians suffering from depression. Among them, 17.0% of physicians showed moderate depression, and 2.6% of physicians exhibited severe depression. The serial-multiple mediation of organizational commitment and positive coping styles in the relationship between psychological capital and depression was significant.Conclusion: The results showed that the psychological capital was sequentially associated with increased organizational commitment, and then increased positive coping styles, which resulted in reduced depression among physicians.


  • Open Access

    Factors Influencing Post-traumatic Stress Symptoms in Chinese Adolescents During the COVID-19 Pandemic

    by Siyuan Ke, Li Sun, Jiawei Zhou, Yini Wang, Tianyi Bu, Haiyun Chu, Jiarun Yang, Wenbo Wang, Wantong Wang, Jiarui Li, et al.

    To investigate the prevalence of post-traumatic stress symptoms (PTSSs) and analyze the influencing factors of PTSS among adolescents in a large sample study during the COVID-19 pandemic, we did a cross-sectional study by collecting demographic data and mental health measurements from a large group of 175,318 adolescents in 32 Chinese provinces and autonomous regions, using the Impact of Event Scale-Revised (IES-R) that was used to measure the PTSS of the participants. The results showed that the prevalence of PTSS was 35.7% in Chinese adolescents during the COVID-19 pandemic. Binary logistic regression analysis showed that, for the personal risk factors, the older age, female gender, the personality domains of extroversion, the irregular sleep schedule, the lack of aerobic exercise, and the lack of peer support were associated with the higher levels of PTSS. The family subjective and objective factors were associated with higher levels of PTSS. Our findings suggested that family factors are the most important factors that affect Chinese adolescents' PTSS due to the longtime home quarantine.


  • Open Access

    The Impact of Transformational Leadership on Physicians’ Performance in China: A Cross-Level Mediation Model

    by Haiyun Chu, Binbin Qiang, Jiawei Zhou, Xiaohui Qiu, Xiuxian Yang, Zhengxue Qiao, Xuejia Song, Erying Zhao, Depin Cao, Yanjie Yang

    Transformational leadership has been becoming increasingly vital to the provision of high-quality health care, particularly during major public health emergencies. The present study aims to investigate the impact of transformational leadership on physicians’ performance and explore the cross-level underlying mechanisms with achievement motivations and coping styles among Chinese physicians. During 2017–2019, 1,527 physicians of 101 departments were recruited from six hospitals in China with a cluster random sampling method. Participants completed several questionnaires regarding their job performance, achievement motivations, coping styles, and transformational leadership. Multilevel mediation effects were tested using cross-level path analysis. The result of this study indicated that transformational leadership was applied well in Chinese medical settings with a score of 101.56 ± 6.42. The hierarchical linear model showed that transformational leadership had a cross-level direct positive effect on physicians’ performance (β = 1.524, p < 0.05). Furthermore, results of cross-level path analyses revealed that transformational leadership contributed to physicians’ performance by sequentially influencing achievement motivations first and then coping styles. In addition, the path “transformational leadership → positive coping (PC) style → physicians’ performance” showed the strongest cross-level indirect effect. In summary, public health leaders should enhance physicians’ performance by promoting individual development, especially achievement motivation and PC style.


  • Open Access

    Interactions Between Glycogen Synthase Kinase-3β Gene Polymorphisms, Negative Life Events, and Susceptibility to Major Depressive Disorder in a Chinese Population

    by Jiarun Yang, Siyuan Ke, Zhengxue Qiao, Xiuxian Yang, Xiaohui Qiu, Xuejia Song, Erying Zhao, Jiawei Zhou, Mingzhe Zhao, Yanjie Yang, et al.

    Background: Recent studies suggest that glycogen synthase kinase (GSK)-3β is involved in the development of major depressive disorder (MDD). The aim of this study was to investigate the interaction between GSK-3β polymorphism (rs6438552, rs334558, and rs2199503) and negative life events in the pathogenesis of major depressive disorder (MDD).Methods: DNA genotyping was performed on peripheral blood leukocytes in 550 patients with MDD and 552 age- and gender-matched controls. The frequency and severity of negative life events were assessed by the Life Events Scale (LES). A chi-square method was employed to assess the gene-environment interaction (G × E).Results: Differences in rs6438552, rs334558, and rs2199503 genotype distributions were observed between MDD patients and controls. Significant G × E interactions between allelic variation of rs6438552, rs334558, and rs2199503 and negative life events were observed. Individuals with negative life events and carrying genotypes of rs6438552 A+, rs334558 A+, and rs2199503G+ have increased the risk of depression.Conclusions: These results indicate that interactions between the GSK-3β rs6438552, rs334558, and rs2199503 polymorphisms and environment increases the risk of developing MDD.


  • Open Access

    The Relationship between Achievement Motivation and Job Performance among Chinese Physicians: A Conditional Process Analysis

    by Botang Guo, Binbin Qiang, Jiawei Zhou, Xiuxian Yang, Xiaohui Qiu, Zhengxue Qiao, Yanjie Yang, Depin Cao

    Background. To explore the relationship between achievement motivation and job performance among physicians, this study investigated the impacts of different personality traits on job performance among the physicians. Methods. This cross‐sectional study was conducted in 2017 and 1,523 physicians from eight tertiary grade A hospitals in Harbin, China. The type of data collected included the achievement motivation of the physicians, job performance, organizational commitment, personality traits, and other demographic variables. To assess and compare the demographic data, independent t‐test and ANOVA were applied. Further, Pearson correlation coefficients were used to evaluate the correlation among the variables. Moderated mediation analysis was performed to test the correlation among the job performance, achievement motivation, organizational commitment, neuroticism, extraversion, openness, agreeableness, and conscientiousness. Results. Achievement motivation directly influences job performance and organizational commitment partially mediates the direct effects of achievement motivation on job performance. Additionally, our findings demonstrated that agreeableness and conscientiousness moderate the strength of the relationships between achievement motivation and job performance mediated by organizational commitment. Conclusion. We propose that hospital managers should pay attention to the personal growth of the physicians and improve their organizational commitment via creating a positive working climate and training for career planning and education. Moreover, managers should identify conscientiousness and agreeableness individuals and increase their responsibilities geared towards improving the performance of the organization.


  • Open Access

    Relationship between Illness Perception and Depressive Symptoms among Type 2 Diabetes Mellitus Patients in China: A Mediating Role of Coping Style

    by Jiarui Li, Xiaohui Qiu, Xiuxian Yang, Jiawei Zhou, Xiongzhao Zhu, Erying Zhao, Zhengxue Qiao, Yanjie Yang, Depin Cao

    Objective. The aims of the present study were to investigate the prevalence of depressive symptoms among type 2 diabetes mellitus (T2DM) patients in China and to explore how coping style influences the relationship between illness perception and depressive symptoms. Methods. Nine hundred and thirty-nine T2DM patients were recruited from a grade 3 Class A hospital in Harbin, China, and asked to complete a demographic questionnaire as well as the Self-rating Depression Scale (SDS), Brief Illness Perception Questionnaire-Revised (IPQ-R), and Medical Coping Modes Questionnaire (MCMQ). Hierarchical linear regression analysis and the bootstrap method were preformed to examine if coping style influenced the relationship between illness perception and depression. Results. The majority of patients (73.59%) exhibited depressive symptoms, including 37.27% with moderate and 6.71% with severe depressive symptoms. Depressive symptoms were more frequent in patients with complications ( ). A resignation coping style partially mediated the influence of illness perception on depressive symptoms. Conclusions. Interventions to improve coping style may reduce the prevalence or severity of depressive symptoms among T2DM patients, potentially enhancing treatment adherence and clinical outcome.


  • Open Access

    Experience of Massive Distance Online Education for Medical Colleges and Universities in China to Counter the COVID-19 Pandemic

    by Jiyang Zhao, Hai Xiao, Yong Li, Da Wen, Peixiang Xu, Yao Fu, Jie Piao, Jiangheng Liu, Depin Cao, Zhaohua Zhong, et al.

    Background As the COVID-19 outbreak influenced teaching in China, Chinese medical colleges and universities carried out massive online education with the participants of more than one million students on the for-profit or non-profit big–data teaching platforms, based on existing online teaching resources and other ways such as MOOC, Micro-course, Live-course and interactive discussion. Methods A questionnaire survey was conducted via two rounds of 56-in-total questions on overall situations, platforms, teaching methods, training, teachers and students’ experiences, and encountered problems for 1747 teachers and 7223 students, which involved 741 courses. Comparative analysis was done on the survey results. Results A majority of teachers and students were satisfied with teaching platforms and effects; large commercial teaching platforms could provide better services; 67.21% of teachers and 64.67% of students preferred live teaching; only 76.84% of teachers and 58.69% of students were systematically trained; weak network, lack of training, overcrowded access to teaching platforms, lack of interaction, lack of efficient real-time evaluation and fatigue were current difficulties. Conclusions Good results of massive distance online education and teachers and students’ satisfaction with teaching platform performance show that online education can be used as a main means to replace traditional classroom education in emergency situations.


  • Open Access

    CACNA1C rs1006737, Threatening Life Events, and Gene–Environment Interaction Predict Major Depressive Disorder

    by Mingzhe Zhao, Jiarun Yang, Xiaohui Qiu, Xiuxian Yang, Zhengxue Qiao, Xuejia Song, Lin Wang, Erying Zhao, Yanjie Yang, Depin Cao

    Introduction: CACNA1C rs1006737 is a novel variant in discovery of replicable associations in major depressive disorder (MDD). However, there have been no specific studies considered effect of environmental pathogens to date examining its clinical significance. In this study we investigated the interaction effect between CACNA1C rs1006737 polymorphism and threatening life events (TLEs) in MDD and carried out a meta-analysis of published findings. Methods: A total of 1,177 consecutive participants were genotyped. Information on exposure to TLEs, socio-demographic data, and history of psychological problems among first-degree relatives was collected. MDD was diagnosed according to the Chinese version of the 24-item Hamilton Rating Scale for Depression. Results: There was a significant interaction effect between CACNA1C rs1006737 polymorphism and TLEs in MDD. A dose–response relationship was found between CACNA1C rs1006737 genotypes and TLEs in MDD. The results of the meta-analysis showed that CACNA1C rs1006737 genotypes interacted with TLEs in MDD. Conclusion: CACNA1C rs1006737 genotype and previous exposure to TLEs interact to influence the risk of developing MDD. We propose that CACNA1C rs1006737 may represent a target for novel pharmacological therapies to prevent or treat MDD.


  • Open Access

    The effects of academic adaptability on academic burnout, immersion in learning, and academic performance among Chinese medical students: a cross-sectional study

    by Yu Jin Xie, De Pin Cao, Tao Sun, Li Bin Yang

    Medical students struggle with a heavy workload during their comparatively long course of study in China. The future of medical science depends largely on whether or not medical students become qualified. This study aims to explore whether medical students’ academic adaptability affects learning outcomes. This paper will not only provide scientific evidence for educators and administrators of medical schools but will also benefit students by improving their aptitude and adaptability through a thorough discussion on their educational environment. We conducted a cross-sectional survey from September to December 2016. A total of 1977 respondents completed the questionnaire with a response rate of 79.08%. A cross-sectional survey was used in this study. Descriptive statistics, factor analysis, General Linear Model (GLM) analysis, standard multiple regression, and hierarchical multiple regression were performed for data analysis using the Statistical Package for Social Sciences software (SPSS Version 19.0, SPSS Inc., Chicago, IL, USA). Out of the 1977 students, 1586 (80.2%) had mean academic adaptability levels over 3. Findings suggested that academic adaptability (Mean = 3.32), immersion in learning (Mean = 3.20), and academic performance (Mean = 3.39), were at the middle level while academic burnout (Mean = 2.17) was at a low level. Academic adaptability of medical students showed a significant negative relation to academic burnout (Beta = − 0.705, P<0.01), there was a significant positive relation between academic adaptability and immersion in learning (Beta = 0.655, P<0.01) and academic performance (Beta = 0.407, P<0.01). Higher levels of academic adaptability are associated with lower levels of burnout and higher levels of immersion in learning and academic performance. It might be helpful for medical schools to consider academic adaptability and ways of enhancing such skills in order to enhance student performance and engagement while in school.