Delio Eulalio Martins

Delio Eulalio Martins

*This is an algorithmically generated author record based on publicly available information.

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Delio Eulalio Martins has a total of 210 co-authors. Here are the top co-authors by number of shared publications:


Latest Publications

  • Open Access

    Cervical Spine Degeneration in Rugby Players: Position-Specific Differences in Radiographic and Clinical Outcomes Among 64 Brazilian Athletes

    by Matheus Neves Castanheira, Yoshinobu Nagasse, Michel Kanas, Nelson Astur, Délio Eulálio Martins Filho, Felipe Neves Simões Monteiro, Marcelo Wajchenberg

    Background: Rugby exposes athletes to high mechanical loads, especially during scrums and tackles, potentially predisposing players to early cervical spine degeneration. This study evaluated the prevalence of degenerative changes in the cervical spine and sagittal alignment alterations in Brazilian rugby athletes, with secondary analyses comparing forwards and backs and examining associations between alignment parameters and pain and disability. Methods: Sixty-four professional rugby athletes underwent cervical spine radiography, and the images were analyzed for degenerative findings and sagittal parameters (cervical lordosis, T1 slope, cervical sagittal vertical axis, and T1–CL mismatch). Pain and disability were assessed using the Visual Analogue Scale (VAS) and Neck Disability Index (NDI). Comparative analyses included Student’s t-test and Fisher’s exact test, while additional exploratory analyses were performed using correlation and multiple linear regression models. Results: Cervical degeneration was present in 20.3% of players. Forwards reported significantly greater pain than backs (VAS: 1.64 ± 1.58 vs. 0.76 ± 0.93; p = 0.007). Deviations in cervical lordosis (>2 SD from normative values) were associated with higher VAS scores (p = 0.024). No significant associations were found between T1 slope or cervical sagittal vertical axis and pain or disability. Conclusions: Forwards demonstrated greater symptom burden and a higher prevalence of cervical degenerative changes, suggesting that positional demands may contribute to early cervical spine alterations. These findings highlight the need for targeted preventive strategies and support future longitudinal investigations to clarify the progression and clinical relevance of cervical misalignment in collision-sport athletes.

  • Open Access

    Perineural hematoma following lumbar injection presenting as a neurosurgical emergency

    by Guilherme Pianowski Pajanoti, Matheus Neves Castanheira, Delio Eulalio Martins, Michel Kanas, Marcelo Wajchenberg, Nelson Astur

    Lower back pain and sciatica account for approximately 40% of work-related absences, with management options ranging from conservative measures, such as rest and analgesia, to surgical intervention. Lumbar epidural steroid injections and facet joint blocks are frequently used for both diagnostic and therapeutic purposes. While most complications are minor (2.4%-9.6%), severe events, including infection, hematoma formation, and spinal cord infarction, have been reported. This case presents a perineural hematoma manifesting as acute radiculopathy, necessitating urgent surgical decompression. The patient

  • Open Access

    VERTEBRAL PLATEAU DEGENERATION AFTER LUMBAR MICRODISCECTOMY: PROSPECTIVE COHORT

    by Matheus Neves Castanheira, Guilherme Pianowski Pajanoti, Michel Kanas, Felipe Neves Monteiro, Delio Eülalio Martins, Marcelo Wajchenberg, Nelson Astur

    Objective: To examine the evolution of degenerative changes in the vertebral plateau of patients with lumbar disc herniation undergoing microdiscectomy, emphasizing the progression of Modic type 1 and 2 changes.

  • Open Access

    Qualitative Evaluation of Paraspinal Musculature After Minimally Invasive Lumbar Decompression: A Prospective Study

    by Ramon Oliveira Soares, Nelson Astur, Lucas Rabello de Oliveira, Michel Kanas, Marcelo Wajchenberg, Delio Eulálio Martins

    Background To quantify fatty infiltration and degree of paraspinal muscle degeneration in patients submitted to tubular microdiscectomy and conventional open microdiscectomy. Methods A prospective cohort of patients was submitted to microdiscectomy for lumbar disc herniation after failure of conservative treatment. Selection of the technique was based on the surgeon’s preference. Analysis of the multifidus muscle was performed using the Goutallier system and the percentage of fat in the muscle. Preoperative and 1-year postoperative T2-weighted magnetic resonance imaging was used, and statistical analysis was carried out using the Wilcoxon test and Spearman correlation test using a significance level of 5%. Results Thirty-two patients were included in the study. The percentage of fatty infiltration in the muscle increased on both sides of the spine 1 year after surgery, although only the ipsilateral side presented statistical significance in patients submitted to conventional microdiscectomy (43.3% preoperative and 57.8% postoperative). Muscular degeneration increased significantly ipsilateral to the disc herniation according to the Goutallier classification (grades 1–2) for both interventions. No statistically significant difference was found for fatty infiltration scores or for the degree of muscular degeneration of the multifidus in the comparative analysis of the methods. Conclusions Muscular damage resulting from surgery of lumbar disc herniation significantly increases fatty infiltration and degeneration of the multifidus. Muscular degeneration was associated with worsening back pain. Clinical Relevance While no significant difference was found between the techniques, the tubular minimally invasive approach shows a tendency for less muscle damage. These findings highlight the importance of minimizing muscle injury during surgery to improve postoperative recovery and long-term outcomes. Level of Evidence 4.


  • ACE I/D polymorphism is a risk factor for the clinical severity of COVID-19 in Brazilian male patients

    by Sandro Soares Almeida, Marcos Fernandes Gregnani, Isabela Moreira Gontijo da Costa, Matheus Matias da Silva, Carolina Bonet Bub, Valmir Oliveira Silvino, Delio Eulalio Martins, Marcelo Wajchenberg

    Background The renin-angiotensin system is potentially involved in the pathogen-host interaction in the disease caused by SARS-CoV-2, since the angiotensin-converting enzyme (ACE) 2 serves as a receptor for the virus. The impact of the pandemic in specific regions and ethnic groups highlights the importance of investigating genetic factors that disrupt the balance of the system in response to SARS-CoV-2 infection, especially in genes with ethnic frequency variations. Therefore, this study aimed to evaluate the influence of the ACE I/D polymorphism on the incidence and severity of COVID-19 in a sample of the Brazilian population. Methods and results 70 severe cases and 355 mild cases patients were evaluated. DNA extraction was performed using a QIAamp DNA Blood Mini kit. Genotyping of ACE I/D polymorphism was performed. Clinical outcomes were obtained from the patients’ records. We found an association between the ACE I/D polymorphism and the incidence or severity of COVID-19 in male participants. Moreover, we observed a relationship between severity and increasing age and body weight and a higher frequency of II genotype individuals among those who had a cough as their symptoms in mild patients. No differences were observed in leukocyte count or other parameters related to the inflammatory response in severe patients. Conclusions Our data showed the influence of the ACE I/D polymorphism on severity of COVID-19 in males, as well as on the occurrence of cough in patients with mild symptoms, with a higher incidence in those carrying the I allele.


  • Open Access

    PERCEPTION OF THE LEARNING CURVE FOR ENDOSCOPIC SPINE PROCEDURES, A SURVEY OF SPINAL SURGEONS IN LATAM

    by Jorge Alvaro González Ross, Neal Sampson, Delio Eulalio Martins, Nelson Astur

    Objective: Full endoscopic uniportal spine procedures offer the advantages of minimally invasive surgery. One of the reasons its worldwide acceptance hasn’t been as expected is because of the perception of a long learning curve. This multicentric survey-based study is designed to identify the perception of the learning curve needed for full endoscopic spine procedures. It was applied to spine surgeons of Latin America and looked to assess the different variables that influence the perception of a learning curve. Methods: A 23-item questionnaire focusing on demographics, experience, and education regarding full endoscopic spine surgery was sent to all registered surgeons in the AO Spine LATAM (a specialty group within the AO Foundation) database. Data analysis was done based on the answers provided. Results: 296 members (out of 1164 AOSpine active members) answered the survey. 54.73% of the responders think that the best way to learn the technique is a combination of an Observership with an expert surgeon, cadaveric or model workshop, and operating with an expert. Most of the responders agree that 26 is the average of surgeries needed to master either the interlaminar approach or the transforaminal approach. Conclusions: The learning curve perceived by spine surgeons is below what is reported in the literature for both interlaminar and transforaminal approaches. Endolif was found to be the least performed procedure. Level of Evidence I; Local and current random sample surveys (or censuses).

  • Open Access

    Lombalgia em estudantes e professores de medicina durante a pandemia: Estudo de coorte retrospectivo

    by Arthur Fiorotto de Mattos, Natália Fortuny de Lima, Marcelo Wajchenberg, Delio Eulalio Martins

    Objetivo Este estudo teve como objetivo determinar a prevalência de lombalgia antes e durante a pandemia, comparando os dois períodos. Métodos Foi aplicado um questionário contendo questões sobre a presença de lombalgia, características sociodemográficas e hábitos que poderiam estar relacionados à essa dor. Resultados Entre as 978 respostas obtidas, a prevalência de lombalgia durante a pandemia foi de 69,94%, o que representou um aumento significativo em relação aos valores do período pré-pandêmico (57,37%). Foi encontrada alta prevalência de lombalgia entre todos os grupos, principalmente entre as mulheres. Alguns fatores foram associados à incidência de lombalgia, como ter problemas de coluna previamente diagnosticados e sedentarismo. Conclusões A prevalência de lombalgia aumentou significativamente durante a pandemia nos grupos estudados. * Estudo desenvolvido na Universidade Anhembi Morumbi, São Paulo, Brasil. Cada autor contribuiu individual e significativamente para o desenvolvimento deste artigo. AFM (0000-0002-9419-7777)*: curadoria de dados (igual), investigação (igual), metodologia (igual), redação-rascunho original (igual) e redação-revisão e edição (igual); NFL (0000-0002-3874-4588)*: curadoria de dados (igual), investigação (igual), metodologia (igual), redação-rascunho original (igual) e redação-revisão e edição (igual); MW (0000-0003-1961-6537)*: conceituação (igual), metodologia (igual), administração do projeto (igual), supervisão (igual), redação-rascunho original (igual) e redação-revisão e edição (igual); e DEM (0000-0001-5510-3507)*: conceituação (lead), curadoria de dados (igual). Investigação (igual), metodologia (igual), administração do projeto (igual), supervisão (igual), redação-rascunho original (igual) e redação-revisão e edição (igual). *ORCID (Open Researcher and Contributor ID). Received: 25 June 2022 Accepted: 08 November 2022 Article published online: 30 August 2023 © 2023. Sociedade Brasileira de Ortopedia e Traumatologia. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/) Thieme Revinter Publicações Ltda. Rua do Matoso 170, Rio de Janeiro, RJ, CEP 20270-135, Brazil


  • Open Access

    SPORTS PRACTICE AFTER LUMBAR DISCECTOMY IN NON-PROFESSIONAL ATHLETES: A CROSS-SECTIONAL STUDY

    by Michel Kanas, Nelson Astur, Leonardo Raymundo Garcia, Lucano Batoni Oliveira, Rafael Bou Roujeile Campiolo, Marcelo Wajchenberg, Delio Eulalio Martins

    Introduction: Most athletes treated for lumbar disc herniation return to play between 3 and 9 months after conservative or surgical treatment. In the last two decades, the general population increased the practice and participation in amateur competitions, being more prone to overload injuries. Objectives: To evaluate sports practice after lumbar discectomy in non-professional athletes. Methods: In the last five years, a digital questionnaire was sent to patients submitted to up to two levels of open discectomy. After signing the informed consent form, the patients were instructed to answer the questionnaire with personal and clinical data related to disc treatment and sports practice after the procedure. Results: Of 182 contacted patients, a hundred answered the questionnaire; 65% practiced regular sports activities before surgery. From patients who practiced sports before surgery, 75.38% returned to sports activities after the procedure. 39.29% returned between 3 and 6 months. Only 12.31% referred to impaired sports performance, while 56.92% performed unaffected, and 21.54% reported improved performance after surgery. Prior sports practice, participation in amateur competitions, and regular core strengthening were significantly associated with sports practice after surgery (P<0,05). Conclusions: From the participants who had already practiced sports before surgery, 75.38% returned after the surgical procedure. Sports practice before surgery, participation in amateur competitions, and regular core strengthening were positively associated with a return to sports practice after lumbar discectomy. The study shows that core strengthening should be encouraged and recommended to all non-professional athletes who intend to return to sports after microdiscectomy surgeries. Level of Evidence: III; Cross-Sectional Retrospective Study.


  • Open Access

    Quality assessment of systematic reviews of surgical treatment of cervical spine degenerative diseases: an overview

    by Nelson Astur, Delio Eulalio Martins, Michel Kanas, Rodrigo Góes Medéa de Mendonça, Aaron T. Creek, Mario Lenza, Marcelo Wajchenberg

    Objective To gather all systematic reviews of surgical treatment of degenerative cervical diseases and assess their quality, conclusions and outcomes. Methods A literature search for systematic reviews of surgical treatment of degenerative cervical diseases was conducted. Studies should have at least one surgical procedure as an intervention. Included studies were assessed for quality through Preferred Reporting Items for Systematic Review and Meta-analysis (PRISMA) and Assessment of Multiple Systematic Reviews (AMSTAR) questionnaires. Quality of studies was rated accordingly to their


  • Next-generation sequencing (NGS) to determine microbiome of herniated intervertebral disc

    by Nelson Astur, Brenno Ferreira Bento Maciel, Andre Mario Doi, Marines Dalla Valle Martino, Marcela Souza Basqueira, Marcelo Wajchenberg, Mario Lenza, Delio Eulalio Martins