Matthew D. Holtkamp
Research Subjects
Matthew D. Holtkamp has a total of 9 co-authors. Here are the top co-authors by number of shared publications:
Ajal Dave
Department of Neurology, Walter Reed National Military Medical Center, Bethesda, Maryland
1 shared publicationBrett J. Theeler
Department of Neurology, Walter Reed National Military Medical Center, 8901 Wisconsin Avenue, Bethesda MD 20889
1 shared publicationGeoffrey Ling
Department of Neurology, Walter Reed National Military Medical Center, 8901 Wisconsin Avenue, Bldg 19, 6th Floor, Neurology, Bethesda, MD, 20889, USA
1 shared publication- James Price
Walter Reed National Military Medical Center, Department of Neurology, United States
1 shared publication Jamie Grimes
Department of Neurology, Walter Reed National Military Medical Center, 8901 Wisconsin Avenue, Bldg 19, 6th Floor, Neurology, Bethesda, MD, 20889, USA
1 shared publicationJohn Finnigan
5th Security Force Assistance Brigade Medical Operations Officer , JBLM 98433, WA
1 shared publication
Latest Publications
- 30 June 2025
- Published by Oxford University Press (OUP) in Military Medicine
- Vol. 190 (9-10) , 219-221
Lessons Learned From the Frontline of GHE in the Indo-Pacific
Medical readiness is critical to military success in the Indo-Pacific, where vast distances complicate evacuation and casualty care. The 5th Security Force Assistance Brigade has conducted over 70 medical assessments since April 2023, improving partner force interoperability from the point of injury through Role II care to enhance operational effectiveness.
- 30 June 2025
- Published by Oxford University Press (OUP) in Military Medicine
- Vol. 190 (9-10) , 219-221
Lessons Learned From the Frontline of GHE in the Indo-Pacific
Medical readiness is critical to military success in the Indo-Pacific, where vast distances complicate evacuation and casualty care. The 5th Security Force Assistance Brigade has conducted over 70 medical assessments since April 2023, improving partner force interoperability from the point of injury through Role II care to enhance operational effectiveness.
- 1 August 2018
- Published by Elsevier in Journal of Stroke and Cerebrovascular Diseases
- Vol. 27 (8) , 2277-2284
A Case for Telestroke in Military Medicine: A Retrospective Analysis of Stroke Cost and Outcomes in U.S. Military Health-Care System
- 1 August 2018
- Published by Elsevier in Journal of Stroke and Cerebrovascular Diseases
- Vol. 27 (8) , 2277-2284
A Case for Telestroke in Military Medicine: A Retrospective Analysis of Stroke Cost and Outcomes in U.S. Military Health-Care System
- 3 May 2018
- Published by Taylor & Francis in Ethnicity & Health
- Vol. 25 (6) , 888-896
Does race matter in universal healthcare? Stroke cost and outcomes in US military health care
Introduction: It is well documented in the US civilian healthcare system that race is correlated with different outcomes for ischemic stroke patients. That healthcare system has wide variations in access to and quality of care. In contrast, the US military healthcare system (MHS) a universal healthcare system where every member has access to the same healthcare benefits. Do racial disparities evident in the civilian healthcare system transfer to the MHS? Methods: Data was collected from the MHS Military Mart (M2) database from calendar years 2010 through 2015. All adult patients with a primary diagnosis of ischemic stroke upon discharge were reviewed. Race was compared across primary outcomes of: (1) IV tPA administration and (2) Disposition destination ‘poor disposition destination or in-hospital mortality’. And secondary outcomes of: (1) Total cost of hospitalization and (2) Length of hospital stay. Relevant demographic and co-morbidities were adjusted with regression analysis. Results: A total of 3623 patients met this study’s parameters. Race was identified in 2661 (73.5%) admissions. Racial composition of this patient sample was: White 1767 (48.8%), African Americans 619 (17.1%), Asian 275 (7.6%), Other or Unknown 962 (26.5%). There was no correlation between race and administration of IV tPA, poor disposition destination or in-hospital mortality. There was a correlation between African Americans and increased cost of hospitalization. This finding was correlated with costs for radiological studies but was not correlated with any increase in the length of stay. Conclusion: Racial disparities evident in the civilian healthcare system do not appear to transfer the universal healthcare system represented by the MHS. Universal healthcare mitigates racial disparities in ischemic stroke admissions.
- 3 May 2018
- Published by Taylor & Francis in Ethnicity & Health
- Vol. 25 (6) , 888-896
Does race matter in universal healthcare? Stroke cost and outcomes in US military health care
Introduction: It is well documented in the US civilian healthcare system that race is correlated with different outcomes for ischemic stroke patients. That healthcare system has wide variations in access to and quality of care. In contrast, the US military healthcare system (MHS) a universal healthcare system where every member has access to the same healthcare benefits. Do racial disparities evident in the civilian healthcare system transfer to the MHS? Methods: Data was collected from the MHS Military Mart (M2) database from calendar years 2010 through 2015. All adult patients with a primary diagnosis of ischemic stroke upon discharge were reviewed. Race was compared across primary outcomes of: (1) IV tPA administration and (2) Disposition destination ‘poor disposition destination or in-hospital mortality’. And secondary outcomes of: (1) Total cost of hospitalization and (2) Length of hospital stay. Relevant demographic and co-morbidities were adjusted with regression analysis. Results: A total of 3623 patients met this study’s parameters. Race was identified in 2661 (73.5%) admissions. Racial composition of this patient sample was: White 1767 (48.8%), African Americans 619 (17.1%), Asian 275 (7.6%), Other or Unknown 962 (26.5%). There was no correlation between race and administration of IV tPA, poor disposition destination or in-hospital mortality. There was a correlation between African Americans and increased cost of hospitalization. This finding was correlated with costs for radiological studies but was not correlated with any increase in the length of stay. Conclusion: Racial disparities evident in the civilian healthcare system do not appear to transfer the universal healthcare system represented by the MHS. Universal healthcare mitigates racial disparities in ischemic stroke admissions.
- 1 March 2018
- Published by Elsevier in Journal of the Neurological Sciences
- Vol. 386, 64-68
Socioeconomic class and universal healthcare: Analysis of stroke cost and outcomes in US military healthcare
- 1 March 2018
- Published by Elsevier in Journal of the Neurological Sciences
- Vol. 386, 64-68
Socioeconomic class and universal healthcare: Analysis of stroke cost and outcomes in US military healthcare
- 1 October 2017
- Published by SAGE Publications in Telemedicine and e-Health
- Vol. 23 (10) , 828-832
Decrease Hospital Spending: There's an App for That! A Retrospective Analysis of Implementation of a Mobile Resident Handbook on Hospital Costs and Disposition
Background: Patient care involves time sensitive decisions. Matching a patient's presenting condition with possible diagnoses requires proper assessment and diagnostic tests. Timely access to necessary information leads to improved patient care, better outcomes, and decreased costs. Introduction: This study evaluated objective outcomes of the implementation of a novel Resident Handbook Application (RHAP) for smart phones. Methods: The RHAP included tools necessary to make proper assessments and to order appropriate tests. The RHAPs effectiveness was accessed using the Military Health System Military Mart database. This database includes patient specific aggregate data, including diagnosis, patient demographics, itemized cost, hospital days, and disposition status. Multivariable analysis was used to compare before and after RHAP implementation, controlling for patient demographics and diagnosis. Internal medicine admission data were used as a control group. Results: There was a statistically significant decrease in laboratory costs and a strong trend toward statistically significant decreases in the cost of radiology performed after implementation of RHAP (p value of Conclusions: The use of the RHAP resulted in decreases in costs in a variety of areas and a decrease in hospital bed days without any apparent negative effect upon patient outcomes or disposition status.
- 1 October 2017
- Published by SAGE Publications in Telemedicine and e-Health
- Vol. 23 (10) , 828-832
Decrease Hospital Spending: There's an App for That! A Retrospective Analysis of Implementation of a Mobile Resident Handbook on Hospital Costs and Disposition
Background: Patient care involves time sensitive decisions. Matching a patient's presenting condition with possible diagnoses requires proper assessment and diagnostic tests. Timely access to necessary information leads to improved patient care, better outcomes, and decreased costs. Introduction: This study evaluated objective outcomes of the implementation of a novel Resident Handbook Application (RHAP) for smart phones. Methods: The RHAP included tools necessary to make proper assessments and to order appropriate tests. The RHAPs effectiveness was accessed using the Military Health System Military Mart database. This database includes patient specific aggregate data, including diagnosis, patient demographics, itemized cost, hospital days, and disposition status. Multivariable analysis was used to compare before and after RHAP implementation, controlling for patient demographics and diagnosis. Internal medicine admission data were used as a control group. Results: There was a statistically significant decrease in laboratory costs and a strong trend toward statistically significant decreases in the cost of radiology performed after implementation of RHAP (p value of Conclusions: The use of the RHAP resulted in decreases in costs in a variety of areas and a decrease in hospital bed days without any apparent negative effect upon patient outcomes or disposition status.
- 1 May 2017
- Published by Oxford University Press (OUP)
- Vol. 182 (5) , 1581
Implementation of the Neurology Resident Handbook Mobile Application Improves Patient Care
Military Medicine is AMSUS’ monthly peer-reviewed journal, with articles including scientific papers, case reports, and editorials. Its objective is to promote awareness of federal medicine by providing a forum for responsible discussion of common ideas and problems relevant to federal healthcare.
- 1 May 2017
- Published by Oxford University Press (OUP)
- Vol. 182 (5) , 1581
Implementation of the Neurology Resident Handbook Mobile Application Improves Patient Care
Military Medicine is AMSUS’ monthly peer-reviewed journal, with articles including scientific papers, case reports, and editorials. Its objective is to promote awareness of federal medicine by providing a forum for responsible discussion of common ideas and problems relevant to federal healthcare.
- 15 April 2016
- Published by Springer Nature in Current Pain and Headache Reports
- Vol. 20 (6) , 1-6
Concussion in the Military: an Evidence-Base Review of mTBI in US Military Personnel Focused on Posttraumatic Headache
Traumatic brain injury (TBI) is defined as an alteration in brain function caused by an external force. Mild TBI or concussion is now well recognized to be a risk of military service as well as participation in athletic sports such as football. Posttraumatic headache (PTH) is the most common symptom after mTBI in US service members. PTH most commonly presents with migraine-like headache features. The following is an overview of the epidemiology, pathophysiology, clinical course, prognosis, complications, and treatment of mTBI and associated comorbidities with a focus on PTH. There is a particular emphasis on emerging evidence-based clinical practice. One important medical consequence of the recognition that mTBI is a highly prevalent among military service members is that the Department of Defense (DoD) is dedicating significant financial and intellectual resources to better understanding and developing treatments for TBI. The identification of the importance of TBI among the US military population has had the added benefit of increasing awareness of this condition among civilian populations, particularly those engaged in both professional and youth sports. The NIH and NSF are also supporting important TBI research. President Obama’s Brain Initiative is also providing additional impetus for these efforts. Unfortunately, the understanding of the acute and chronic effects of mTBI on the brain remains limited. Gratefully, there is hope that through innovative research, there will be advances in elucidating the underlying pathophysiology, which will lead to clinical and prognostic indicators, ultimately resulting in new treatment options for this very complicated set of disorders.
- 15 April 2016
- Published by Springer Nature in Current Pain and Headache Reports
- Vol. 20 (6) , 1-6
Concussion in the Military: an Evidence-Base Review of mTBI in US Military Personnel Focused on Posttraumatic Headache
Traumatic brain injury (TBI) is defined as an alteration in brain function caused by an external force. Mild TBI or concussion is now well recognized to be a risk of military service as well as participation in athletic sports such as football. Posttraumatic headache (PTH) is the most common symptom after mTBI in US service members. PTH most commonly presents with migraine-like headache features. The following is an overview of the epidemiology, pathophysiology, clinical course, prognosis, complications, and treatment of mTBI and associated comorbidities with a focus on PTH. There is a particular emphasis on emerging evidence-based clinical practice. One important medical consequence of the recognition that mTBI is a highly prevalent among military service members is that the Department of Defense (DoD) is dedicating significant financial and intellectual resources to better understanding and developing treatments for TBI. The identification of the importance of TBI among the US military population has had the added benefit of increasing awareness of this condition among civilian populations, particularly those engaged in both professional and youth sports. The NIH and NSF are also supporting important TBI research. President Obama’s Brain Initiative is also providing additional impetus for these efforts. Unfortunately, the understanding of the acute and chronic effects of mTBI on the brain remains limited. Gratefully, there is hope that through innovative research, there will be advances in elucidating the underlying pathophysiology, which will lead to clinical and prognostic indicators, ultimately resulting in new treatment options for this very complicated set of disorders.