João Antonio Matheus Guimarães

João Antonio Matheus Guimarães

*This is an algorithmically generated author record based on publicly available information.

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João Antonio Matheus Guimarães has a total of 177 co-authors. Here are the top co-authors by number of shared publications:


Latest Publications

  • Open Access

    Combined Anterior Cruciate Ligament Reconstruction and Extra‐articular Tenodesis Using the Iliotibial Band With Femoral Press‐Fit Fixation: A Low‐Cost and Reproducible Technique

    by José Leonardo Rocha de Faria, Felipe Galvão Abreu, Vitor Barion de Pádua, Valdeci Manoel de Oliveira, Rafael Erthal de Paula, Yuri Di Cavalcanti, Naasson Trindade Cavanellas, José Paulo Gabbi Aramburú Filho, João Antonio Matheus Guimarães, Geraldo da Rocha Motta Filho, et al.

    The addition of a lateral extra‐articular reinforcement to anterior cruciate ligament reconstruction has been shown to enhance rotational stability and protect the intra‐articular graft. Although several techniques using the iliotibial band have been described, most rely on fixation devices that increase surgical cost and complexity. This Technical Note describes a low‐cost, reproducible technique for combined anterior cruciate ligament reconstruction and lateral extra‐articular tenodesis using the iliotibial band, with femoral press‐fit fixation for both grafts. This approach eliminates the need for fixation hardware, simplifies the procedure, and may facilitate its adoption in a wide range of surgical settings worldwide.

  • Open Access

    A Posterior Transosseous S1 Pedicle Approach for Accessing the Superior Hypogastric Plexus: A Hypothesis

    by Andre Luiz Loyelo Barcellos, Clara Martins Albuquerque, João Antonio Matheus Guimarães

  • Open Access

    Femoral Stem Subsidence in Total Hip Arthroplasty: Comparison between Fixation Principles

    by André N. B. M. de Macedo, Lourenço P. Peixoto, João A. M. Guimarães, Conrado T. Laett

    To compare the magnitude of subsidence between single- (SW) and double-wedge (DW) femoral stems in primary total hip arthroplasties (THAs), and to identify factors associated with clinically relevant subsidence. Retrospective cohort study with 82 patients (164 hips) undergoing bilateral THA between 2012 and 2022, each receiving type-I (Corail) and -II (Summit) stems, both manufactured by DePuy Synthes. Subsidence was measured radiographically up to 6 months postoperatively and was considered clinically relevant when greater than 3 mm. Radiographic variables included cortical enlargement index (CEI) and canal fill rate (CFR). Statistical analyses included paired t-test, logistic regression, and Spearman correlation. The mean subsidence was 1.93 ± 1.16 mm in type-I stems and 2.23 ± 1.57 mm in type-II (p = 0.181). Clinically relevant subsidence occurred in 18.2% of type-I stems and 31.7% of type-II (OR = 2.07; p = 0.050). Greater subsidence was observed in the first surgery in bilateral arthroplasties (p = 0.006). There was no significant correlation between subsidence, age, body mass index (BMI), CEI, or CFR. The DW stems were associated with a higher risk of clinically relevant subsidence. In bilateral THA, subsidence is more pronounced at first surgery, with no detectable influence of demographic or radiographic factors.

  • Open Access

    Afundamento da haste femoral em artroplastia total do quadril: Comparação entre princípios de fixação

    by André N. B. M. de Macedo, Lourenço P. Peixoto, João A. M. Guimarães, Conrado T. Laett

    Resumo: Comparar a magnitude do afundamento entre hastes femorais de cunha única (CU) e dupla (CD) em artroplastias totais do quadril (ATQs) primárias e identificar fatores associados a afundamentos clinicamente relevantes. Estudo de coorte retrospectiva com 82 pacientes (164 quadris) submetidos a ATQ bilateral entre 2012 e 2022, cada um recebendo haste tipo I (Corail) e II (Summit), ambas fabricadas pela DePuy Synthes. O afundamento foi mensurado radiograficamente até 6 meses de pós-operatório, sendo considerado clinicamente relevante quando superior a 3 mm. Variáveis radiográficas incluíram o índice de alargamento cortical (IAC) e a taxa de preenchimento do canal (TPC). As análises estatísticas incluíram teste t pareado, regressão logística e correlação de Spearman. O afundamento médio foi de 1,93 ± 1,16 mm nas hastes tipo I e 2,23 ± 1,57 mm nas tipo II (p = 0,181). Afundamentos clinicamente relevantes ocorreram em 18,2% das hastes tipo I e 31,7% das tipo II (OR = 2,07; p = 0,050). Observou-se maior afundamento na primeira cirurgia em artroplastias bilaterais (p = 0,006). Não houve correlação significativa entre afundamento e idade, IMC, IAC ou TPC. As hastes de CD apresentaram maior risco de afundamento clinicamente relevante. Em ATQs bilaterais, o afundamento é mais pronunciado na primeira cirurgia, sem influência detectável de fatores demográficos ou radiográficos.

  • Open Access

    Protocol for a Randomized Clinical Trial to Assess the Effects of Extra-Articular Strengthening in Anterior Cruciate Ligament Reconstruction on the Clinical and Functional Condition of High-Performance Athletes

    by Thiago Lemos, Conrado T. Laett, José P. G. Aramburu Filho, Geraldo R. Motta Filho, João M. Guimarães, José Leonardo R. Faria

    To describe a randomized clinical trial designed to evaluate the impact of three extra-articular reinforcement techniques combined with anterior cruciate ligament reconstruction (ACLR) on postoperative muscle function, activity levels, and return-to-sport in high-performance athletes. The primary hypothesis is that these techniques will differentially influence joint stability and recovery trajectories. A prospective, quasirandomized, single-blind trial intending to enroll 220 athletes, between 18 and 45-years-old, with isolated ACL injuries. Participants will be allocated via block randomization to one of three procedures: lateral extra-articular tenodesis (LET), involving fixation of a iliotibial band strip near the anterolateral ligament (ALL) at 30° knee flexion for rotational stability; single-bundle ALL reconstruction (ALL-S), using a gracilis graft between the femoral epicondyle and Gerdy's tubercle; and double-bundle ALL (ALL-D), employing two graft limbs in a double tibial tunnel located between Gerdy's tubercle and the fibular head, with a single femoral fixation at the anatomical position of the ALL. Assessments will occur preoperatively and at 3, 6, 9, 12, and 24-months postsurgery, including joint laxity, quadriceps morphology, functional performance, and knee isokinetic strength. Furthermore, self-reported outcomes, such as the International Knee Documentation Committee's (IKDC), 36-Item Short Form Health Survey (SF-36), and Tegner scale, will also be collected. Linear mixed-effects models will analyze outcomes, adjusting for meniscal repair status. Upon completion, this study is expected to identify the most effective extra-articular technique for restoring knee stability and function, potentially guiding surgical decision-making. Our findings may optimize rehabilitation protocols and reduce reinjury rates in athletes. This protocol describes a comprehensive clinical trial that addresses important gaps in current knowledge regarding optimal surgical approaches for ACLR in athletes.

  • Open Access

    Protocolo para um ensaio clínico randomizado de avaliação dos efeitos do fortalecimento extra-articular na reconstrução do ligamento cruzado anterior sobre as condições clínicas e funcionais de atletas de alto rendimento

    by Thiago Lemos, Conrado T. Laett, José P. G. Aramburu Filho, Geraldo R. Motta Filho, João M. Guimarães, José Leonardo R. Faria

    Resumo: Descrever um ensaio clínico que pretende avaliar o impacto de técnicas de reforço extra-articular combinadas com a reconstrução do ligamento cruzado anterior (R-LCA) na função muscular, atividade física e retorno ao esporte em atletas de alto rendimento. A principal hipótese é que essas técnicas influenciarão diferentemente a estabilidade articular e a recuperação. Estudo prospectivo, quase-aleatório e simples-cego pretendendo incluir 220 atletas, entre 18 e 45 anos de idade, com lesões isoladas do LCA. Os participantes serão randomizados em blocos para um dos três procedimentos: tenodese extra-articular lateral (TEL), consistindo na fixação de uma faixa da banda iliotibial próximo à origem femoral do ligamento anterolateral (LAL) com 30° de flexão do joelho para estabilidade rotatória; reconstrução do LAL com feixe único (LAL-U) utilizando um enxerto de tendão Grácil entre o Cabeça da fíbula e a tuberosidade de Gerdy; ou LAL com feixe duplo (LAL-D), empregando dois ramos do enxerto em um duplo tunel tibial entre o tuberculo de gerdy e a cabeça da fibula e fixação femoral unica na posição anatomica do LAL. As avaliações ocorrerão no pré-operatório e aos 3, 6, 9, 12 e 24 meses pós-cirúrgico, incluindo lassidão articular, morfologia do quadríceps, desempenho funcional e força isocinética. Além disso, dados autorrelatados, como o da International Knee Documentation Committee (IKDC), 36-Item Short Form Health Survey (SF-36), e a escala de Tegner também serão coletados. Modelos lineares de efeitos mistos serão usados, para análise, ajustando-se ao reparo meniscal. Após a conclusão do estudo, esperamos identificar a técnica de reforço extra-articular mais eficaz para restaurar estabilidade e função do joelho, orientando decisões cirúrgicas. Os achados podem otimizar a reabilitação e reduzir recidivas em atletas. Este protocolo aborda um ensaio clínico detalhado, referente a lacunas importantes no conhecimento atual sobre as melhores abordagens cirúrgicas para R-LCA em atletas.

  • Open Access

    Elderly men and women with similar areal bone density show significant differences in bone microstructure and fracture pattern

    by Eduardo Medeiros Ferreira da Gama, Leonardo Vieira Neto, Francisco de Paula Paranhos-Neto, Laura Maria Carvalho Mendonça, Luiza Silva Machado de Andrade, Miguel Madeira, Guilherme Cardenaz de Souza, João Antonio Matheus Guimarães, Maria Eugênia Leite Duarte, Maria Lucia Fleiuss Farias

    Objective: To compare bone microarchitecture and fracture patterns between elderly men and women with similar spine and hip bone mineral densities (BMDs). Subjects and methods: Twenty-eight men and 84 age-BMI-BMD-matched women aged 65 years and older with at least one major osteoporotic fracture underwent laboratory tests, dual-energy X-ray absorptiometry (DXA), high-resolution peripheral quantitative computed tomography (HR-pQCT), and trabecular bone score (TBS). Results: There were no sex differences in biochemistry, BMD or lowest T-scores. TBS values were low in 67% [...] ABSTRACT Objective: To compare bone microarchitecture and fracture patterns between elderly men and women with similar spine and hip bone mineral densities (BMDs). Subjects and methods: Twenty-eight men and 84 age-BMI-BMD-matched women aged 65 years and older with at least one major osteoporotic fracture underwent laboratory tests, dual-energy X-ray absorptiometry (DXA), high-resolution peripheral quantitative computed tomography (HR-pQCT), and trabecular bone score (TBS). Results: There were no sex differences in biochemistry, BMD or lowest T-scores. TBS values were low in 67%

  • Open Access

    NATIONAL INSTITUTE OF TRAUMATOLOGY AND ORTHOPEDICS: A BIBLIOMETRIC STUDY

    by Rebecca Fiorani de Oliveira Nascimento, João Antonio Matheus Guimarães, Patrícia Cristina dos Santos Costa

    Objective: This study aimed to map the scientific production of the National Institute of Traumatology and Orthopedics (INTO) over its 50 years of history. Methods: We conducted a descriptive bibliometric study in the PubMed, Scopus, and BVS databases, retrieving 522 articles published between 2007 and 2024. We identified the co-citation networks of INTO-affiliated authors, the keyword networks with the main topics addressed in the publications, and the institution's interaction network with other research and teaching entities. Results: There was a progressive growth in publications linked to INTO. In the last six years (2019–2024), the annual average number of publications increased by 44.83% compared with the previous period. The keywords with the highest co-occurrence were related to applied research, mainly with an epidemiological profile, but also to different study designs in basic and translational research. Conclusions: The analysis revealed a higher frequency of collaboration with public universities (UFRJ, UFF, UERJ, and USP). The institution's scientific production presented a well-articulated scientific collaboration network. Part of INTO's mission was evidenced through its work in public health research for health promotion in orthopedics and its contribution to the production of data for the formulation of public policies. Level of Evidence V; Descriptive Studies with Qualitative Approach.

  • Open Access

    Alterations in coagulation profile of patients with periprosthetic joint infections

    by Augusto Carlos Maciel Saraiva, Alan de Paula Mozella, Hugo Alexandre de Araujo Barros Cobra, Osamu de Sandes Kimura, João Antonio Matheus Guimarães, Helton Defino, Ana Carolina Leal

    Purpose: This study aims to evaluate changes in the coagulation profile of patients with knee periprosthetic infections (PJI) and determine its diagnostic value in this complication. Methods: A prospective study was conducted with 112 patients who underwent revision surgery for total knee arthroplasty in a single tertiary hospital between January 2021 and December 2022. Results: 51 patients were diagnosed with PJI. D-dimer (p = 0.001), fibrinogen (p = 0.0007), platelets (0.01), and international normalized ratio (p = 0.01) were significantly higher in patients with PJI. Conclusions: Patients with PJI display altered coagulation profile. The evaluation of coagulation-related markers has limited value for diagnosing PJI. Further studies are needed to understand the impact of such alterations on patients’ outcomes.


  • Open Access

    Clinical insights into circulating free-DNA in patients with bone sarcomas and ewing sarcoma

    by Veronica Aran, Amanda Santos Cavalcanti, Walter Meohas, Bruna Canteri, Jamila Alessandra Perini, Jesus Pino Minguez, João Antônio Matheus Guimarães, Vivaldo Moura Neto, Maria Eugênia Leite Duarte