Dimitris Mandalidis

Background: Neurodynamic techniques are commonly used to improve neural mobility and musculoskeletal function, but their effects on muscle mechanical properties remain unclear. This study investigated the acute effects of femoral nerve slider, femoral nerve tensioner, and static stretching interventions on the rectus femoris and vastus medialis muscles. Methods: Thirty healthy adults (18–35 years) were non-randomly allocated using a predetermined alternating sequence to a femoral nerve slider (n = 10), femoral nerve tensioner (n = 10), or static stretching group (n = 10). No sham or no-intervention control group was included. Muscle mechanical properties were assessed before and immediately after the intervention using the MyotonPRO (Myoton AS, Tallinn, Estonia). Outcomes included muscle tone, stiffness, logarithmic decrement, relaxation time, and creep. A three-way mixed repeated-measures ANOVA was performed. Results: No statistically significant differences in pre–post changes were detected among the three intervention groups for any of the examined mechanical parameters. Significant main effects of time were found for stiffness (p = 0.026) and creep (p = 0.005), indicating overall reductions from pre- to post-assessment. Significant time × muscle interactions were identified for relaxation time (p = 0.029) and creep (p = 0.002), indicating different temporal patterns between the rectus femoris and vastus medialis. Following Holm adjustment of the follow-up comparisons, the pre–post reduction in the vastus medialis remained statistically significant for creep but not for relaxation time. The rectus femoris demonstrated greater stiffness and logarithmic decrement values, whereas the vastus medialis exhibited greater relaxation time values. Conclusions: No statistically significant differences in immediate pre–post changes in quadriceps muscle mechanical properties were detected among the femoral nerve slider, femoral nerve tensioner, and static stretching groups. Temporal and muscle-specific patterns were observed for selected mechanical parameters; however, these findings should not be interpreted as evidence of equivalence between the interventions.

Background/Objectives: This study aims to evaluate the effectiveness of binaural beats (BB) on the autonomic nervous system (ANS), kinesiophobia of reinjury and fitness biomarkers in professional athletes with chronic musculoskeletal injuries. Methods: A total of 54 athletes aged 18–25 years, engaged in open-skill sports and experiencing chronic lower-limb injuries for over three months, will be recruited. They will be randomly assigned to one of three groups: an intervention group, a placebo group, and a control group. All athletes will undergo a 15 min auditory intervention five times per week for four weeks. The intervention group will listen to BB embedded in music at high beta and gamma frequencies (30–100 Hz) with guided instructions. The placebo group will receive placebo BB within the same music framework, while the control group will listen only to the music background. Assessments will be conducted at baseline, immediately post-intervention, and at a 4-week follow-up. The primary outcomes will be kinesiophobia of reinjury, ANS function, and heart rate variability (HRV), assessed using the Tampa Scale of Kinesiophobia (TSK-17), Sympathetic Skin Response (SSR), and HRV analysis, respectively. Secondary outcomes will include sport-related anxiety and pain beliefs, assessed using the Sport Competition Anxiety Test (SCAT-15) and the Pain Beliefs and Perceptions Inventory (PBPI-16), respectively; handgrip strength, assessed using the Hand Grip Test; and fitness-related biomarkers, including maximal oxygen uptake (VO₂max) and blood lactate concentration. Conclusions: These findings may provide evidence supporting BB as a complementary, non-invasive intervention to enhance psychological and physiological rehabilitation in injured athletes. Ethics and Dissemination: The study has received ethical approval and is registered on ClinicalTrials.gov. Findings will be disseminated through peer-reviewed publications, conferences, and academic presentations.

Background/Objectives: Emerging evidence suggests the presence of associations in joint mobility along anatomically defined myofascial continuities, indicating that joint mobility may co-vary across anatomically distant regions. This study aimed to investigate the correlations between the active range of motion (ROM) of joints belonging to the same myofascial chain in healthy, physically active individuals. Methods: Active ROM was measured in 61 adults (21 males and 40 females) at joints contributing to four myofascial chains: the superficial front line (SFL), superficial back line (SBL), functional front line (FFL), and functional back line (FBL), using an inertial measurement unit. Partial Pearson’s correlation coefficients (r), controlling for sex, were calculated to examine the relationships between joint ROM values within lines, with statistical corrections applied when necessary. Results: Significant, yet weak to moderate in most cases, partial correlation coefficients were identified among joints in the upper SFL (0.32–0.44), the lower SBL (0.42–0.44), along the FFL (0.29–0.51), and between the lower segments of the BFL (0.48–0.60). Conclusions: While some joint ROMs within myofascial chains demonstrate weak-to-strong associations, overall interdependence appears mode- and region-specific. These findings suggest that factors beyond fascial continuity, such as neuromuscular control, joint structure, and movement habits, are likely to contribute to ROM variability.

Single-leg squats are commonly used to assess lower-limb strength and alignment; however, their application for evaluating postural control remains underexplored. This study assessed the reliability and agreement of postural control measures within and between unipedal squat variations. Twenty-eight physically active adults performed a conventional single-leg squat (CSLSQ), the anterior excursion of the Y-Balance Test (ANYBT), and a forward step-down (FRSTD) with both limbs on two occasions, 5–7 days apart. The mean values of five trials were analyzed for center-of-pressure (COP) 95% confidence ellipse area (95%CEA), path length (PL), velocity (VL), and mediolateral and anteroposterior variability (RMS-X and RMS-Y). Most COP variables demonstrated good-to-excellent reliability (ICC = 0.780–0.948), whereas RMS-X showed lower reliability (ICC = 0.367–0.803) and higher measurement error across limbs. The FRSTD demonstrated high ICCs (0.780–0.948) and low measurement error, comparable to the CSLSQ (0.794–0.940) and generally higher than the ANYBT (0.790–0.895), regardless of limb. Overall, the dominant limb exhibited higher ICCs and lower measurement error than the non-dominant limb. Inter-task agreement was greatest between the CSLSQ and FRSTD, primarily on the dominant limb, indicating greater potential interchangeability for selected COP metrics (95% CEA, VL, and RMS-Y). These findings may assist clinicians and sports scientists in selecting appropriate single-leg squat tasks and COP measures for assessment.

Unaccustomed eccentric exercise is well established to induce exercise-induced muscle damage (EIMD), characterized by transient strength loss, delayed onset muscle soreness (DOMS), reduced range of motion, and proprioceptive disturbances. While limb dominance has been proposed as a potential modulator of susceptibility to EIMD, evidence remains inconclusive. This exploratory study aimed to compare alterations in muscle damage indices between dominant and non-dominant knee extensors 48 h after eccentric isokinetic exercise. Eighteen physically active young women (23 ± 2 years) completed two eccentric exercise sessions (5 × 15 maximal contractions at 60°/s), one per limb, with sessions separated by 24–30 days. For all participants, testing was conducted during the early follicular phase. Muscle strength (isometric and eccentric peak torque), DOMS (palpation and pain pressure threshold), range of motion, fatigue index, and position sense were assessed pre- and 48 h post-exercise. Significant reductions in isometric and eccentric peak torque, increased DOMS, impaired position sense, and altered fatigue index were observed 48 h post-exercise in the exercised limb (p < 0.001), with no differences between dominant and non-dominant limbs across all indices. These findings demonstrate that limb dominance does not influence the magnitude of EIMD in knee extensors of young women. Practical implications include equal consideration of both limbs in eccentric training, rehabilitation, and injury prevention programs.

Foot hyperpronation is a common anatomical misalignment that may contribute to the development of both localized and distant musculoskeletal overuse injuries. Advancements in modern technology may enable the detection of biomechanical changes in dynamic conditions that cannot be captured through conventional foot alignment assessments. This study aimed to investigate potential differences in spatiotemporal, dynamic, and center of pressure (COP)-related gait parameters, between individuals with foot hyperpronation (n = 21) and those with a neutral foot type (n = 21) under various walking conditions, using an instrumented treadmill. These conditions included walking downhill at −20% slope at 3.5 km·h⁻¹, and at −10% slope at 5.0 km·h⁻¹, level (0%) at 5.0 km·h⁻¹, and uphill at +10% slope at 3.5 km·h⁻¹ and +20% slope at 2.5 km·h⁻¹, each lasting five minutes. The results showed no significant differences in stride length and time, foot rotation, step width, cadence, or gait phase durations between the two groups. However, individuals with hyperpronated feet exhibited a more forward and mediolaterally displaced COP, higher vertical ground reaction forces (vGRFs) at the midfoot, and lower vGRFs at the lateral forefoot. Instrumented treadmills enable clinicians and sports scientists to detect specific traits in individuals with foot hyperpronation, which would otherwise go undetected through static assessments.

Foot hyperpronation is a common anatomical misalignment that may contribute to the development of both localized and distant musculoskeletal overuse injuries. Advancements in modern technology may enable the detection of biomechanical changes in dynamic conditions that cannot be captured through conventional foot alignment assessments. The study aimed to investigate potential differences in spatiotemporal, dynamic and center of pressure (COP)-related gait parameters, between individuals with foot hyperpronation (n=21) and those with a neutral foot type (n=21) under various walking conditions, using an instrumented treadmill. These conditions included walking downhill at −20% slope at 3.5 km·h-1, and at −10% slope at 5.0 km·h-1, level (0%) at 5.0 km·h-1, and uphill at +10% slope at 3.5 km·h-1 and +20% slope at 2.5 km·h-1, each lasting five minutes. The results showed no significant differences in stride length and time, foot rotation, step width, cadence, or gait phase durations between the two groups. However, individuals with hyperpronated feet exhibited a more forward and mediolaterally displaced COP, higher vertical ground reaction forces (vGRFs) at the midfoot, and lower vGRFs at the lateral forefoot. Instrumented treadmills enable clinicians and sports scientists to detect specific traits in individuals with foot hyperpronation, which would otherwise go undetected through static assessments.

Hiking offers both recreational enjoyment and physical challenges, requiring speed adjustments when traversing uphill and downhill slopes. These adjustments prompt compensatory responses in kinematics and kinetics to mitigate fatigue and musculoskeletal strains. The study aimed to explore the impact of slope-specific walking speeds on spatiotemporal gait parameters, vertical ground reaction forces (vGRFs), and position of the center of pressure (COP) during uphill and downhill walking. Thirty-two healthy individuals completed five 4-min walks on an instrumented treadmill set to 0% (level), +10%, and +20% (uphill), and −10% and −20% (downhill), slopes, at 5.0, 3.5, 2.5, 5.0 and 3.5 km h⁻¹, respectively. Uphill walking led to reduced stride length and cadence, increased foot rotation, step time, and durations of stance, swing, and double-stance phases. Conversely, downhill walking exhibited decreased step length, step time, and durations of stance, swing, and double-stance phases but increased step width and cadence compared to level walking. Speed adjustments to accommodate slope led to reduced vGRFs for uphill and downhill walking. Additionally, the COP shifted forward during uphill and backward during downhill walking and displaced laterally as walking became more demanding. The observed responses indicate adaptations aimed at maintaining postural control, reducing excessive load application, and optimizing energy expenditure on sloping terrain.