Noriko Aramaki-Hattori
Current Organizations / Institutes
The organizations/institutes from the scholar's latest article
Noriko Aramaki-Hattori has a total of 117 co-authors. Here are the top co-authors by number of shared publications:
Akira Miyakoshi
14 shared publications- Hitoshi Abe
Institute of Materials Structure Science High Energy Accelerator Research Organization Tsukuba Ibaraki Japan
14 shared publications - Junko Kuramoto
Department of Pathology, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo, 160-8582, Japan.
14 shared publications Kanehisa Kojoh
14 shared publications- Ken J. Ishii
Division of Vaccine Science, Department of Microbiology and Immunology, The Institute of Medical Science, The University of Tokyo, Tokyo, Japan
14 shared publications - Masayuki Shimoda
Department of Pathology, The Jikei University School of Medicine, Tokyo, Japan
14 shared publications
Latest Publications
- Open Access
- 18 December 2023
- Published by MDPI AG in Biomedicines
- Vol. 11 (12) , 3350
Regeneration of Panniculus Carnosus Muscle in Fetal Mice Is Characterized by the Presence of Actin Cables
Mammalian skin, including human and mouse skin, does not regenerate completely after injury; it is repaired, leaving a scar. However, it is known that skin wounds up to a certain stage of embryonic development can regenerate. The mechanism behind the transition from regeneration to scar formation is not fully understood. Panniculus carnosus muscle (PCM) is present beneath the dermal fat layer and is a very important tissue for wound contraction. In rodents, PCM is present throughout the body. In humans, on the other hand, it disappears and becomes a shallow fascia on the trunk. Fetal cutaneous wounds, including PCM made until embryonic day 13 (E13), regenerate completely, but not beyond E14. We visualized the previously uncharacterized development of PCM in the fetus and investigated the temporal and spatial changes in PCM at different developmental stages, ranging from full regeneration to non-regeneration. Furthermore, we report that E13 epidermal closure occurs through actin cables, which are bundles of actomyosin formed at wound margins. The wound healing process of PCM suggests that actin cables may also be associated with PCM. Our findings reveal that PCM regenerates through a similar mechanism.
- 18 December 2023
- Published by MDPI AG in Biomedicines
- Vol. 11 (12) , 3350
Open AccessRegeneration of Panniculus Carnosus Muscle in Fetal Mice Is Characterized by the Presence of Actin Cables
Mammalian skin, including human and mouse skin, does not regenerate completely after injury; it is repaired, leaving a scar. However, it is known that skin wounds up to a certain stage of embryonic development can regenerate. The mechanism behind the transition from regeneration to scar formation is not fully understood. Panniculus carnosus muscle (PCM) is present beneath the dermal fat layer and is a very important tissue for wound contraction. In rodents, PCM is present throughout the body. In humans, on the other hand, it disappears and becomes a shallow fascia on the trunk. Fetal cutaneous wounds, including PCM made until embryonic day 13 (E13), regenerate completely, but not beyond E14. We visualized the previously uncharacterized development of PCM in the fetus and investigated the temporal and spatial changes in PCM at different developmental stages, ranging from full regeneration to non-regeneration. Furthermore, we report that E13 epidermal closure occurs through actin cables, which are bundles of actomyosin formed at wound margins. The wound healing process of PCM suggests that actin cables may also be associated with PCM. Our findings reveal that PCM regenerates through a similar mechanism.