Hoo Young Lee

Background/Objectives: Caregivers of infants with congenital muscular torticollis (CMT) frequently seek information online, although the accuracy, clarity, and safety of web-based content remain variable. As large language models (LLMs) are increasingly used as health information tools, their reliability for caregiver education requires systematic evaluation. This study aimed to assess the reproducibility and quality of ChatGPT-5.1 responses to caregiver-centered questions regarding CMT. Methods: A set of 17 questions was developed through a Delphi process involving clinicians and caregivers to ensure relevance and comprehensiveness. ChatGPT generated responses in two independent sessions. Reproducibility was assessed using TF–IDF cosine similarity and embedding-based semantic similarity. Ten clinical experts evaluated each response for accuracy, readability, safety, and overall quality using a 4-point Likert scale. Results: ChatGPT demonstrated moderate lexical consistency (mean TF–IDF similarity 0.75) and high semantic stability (mean embedding similarity 0.92). Expert ratings indicated moderate to good performance across domains, with mean scores of 3.0 for accuracy, 3.6 for readability, 3.1 for safety, and 3.1 for overall quality. However, several responses exhibited deficiencies, particularly due to omission of key cautions, oversimplification, or insufficient clinical detail. Conclusions: While ChatGPT provides fluent and generally accurate information about CMT, the observed variability across topics underscores the importance of human oversight and content refinement prior to integration into caregiver-facing educational materials.

Kim SK, et al. Korean J Neurotrauma. 2026 Oct;22(4):374-389. https://doi.org/10.13004/kjnt.2026.22.e50

Shin KH, et al. Korean J Neurotrauma. 2026 Apr;22(2):119-134. https://doi.org/10.13004/kjnt.2026.22.e19

Jeong SH, et al. Korean J Neurotrauma. 2026 Jan;22(1):24-35. https://doi.org/10.13004/kjnt.2026.22.e9

Lee HY, et al. Brain Neurorehabil. 2025 Jul;18(2):e5. https://doi.org/10.12786/bn.2025.18.e5

Objective: To identify the prevalence and factors associated with T-score discordance between the spine and hip, as well as between the paretic and non-paretic hips in hemiplegic stroke patients, this study investigated bone mineral density (BMD) patterns. Bone loss predominantly affects the paretic hip after a stroke, and typical clinical assessments using dual-energy X-ray absorptiometry (DXA) that scan the lumbar spine (LS) and a single hip may overlook an osteoporosis diagnosis. This oversight could potentially lead to suboptimal treatment for stroke patients.Methods: This study was a multicenter retrospective analysis of 540 patients admitted for stroke rehabilitation between October 2014 and February 2022, who underwent DXA of LS and bilateral hips.Results: The prevalence rates of concordance, low LS discordance, and low hip discordance between the LS and hips were 48.2%, 12.2%, and 39.6%, respectively. The discordance rate between bilateral hips was 17.0%. The paretic side had significantly lower total hip T-scores than the non-paretic side (p<0.001). Notably low paretic hip discordance was more prevalent during the chronic phase. DXA scans of the LS and both hips revealed a 0.7%–0.9% higher major discordance compared to LS and single hip DXA scans. The multivariate analysis revealed a significant correlation between a low paretic hip discordance and cognitive impairment (adjusted odds ratio 0.071, 95% confidence interval 0.931–1.003, p<0.05).Conclusion: Since stroke survivors are at high risk for hip fractures, comprehensive BMD assessments, which include LS and bilateral hips, should be considered for post-stroke osteoporosis care to enhance diagnostic accuracy and timely treatment.

Kim DY, et al. Brain Neurorehabil. 2023 Jul;16(2):e18. https://doi.org/10.12786/bn.2023.16.e18

Lee HY, et al. Korean J Neurotrauma. 2022 Nov;19:e1. https://doi.org/10.13004/kjnt.2023.19.e1

Lee HY, et al. Brain Neurorehabil. 2022 Mar;15(1):e4. https://doi.org/10.12786/bn.2022.15.e4

Hypoxic–ischemic encephalopathy (HIE) is a devastating neonatal brain condition caused by lack of oxygen and limited blood flow. Environmental enrichment (EE) is a classic paradigm with a complex stimulation of physical, cognitive, and social components. EE can exert neuroplasticity and neuroprotective effects in immature brains. However, the exact mechanism of EE on the chronic condition of HIE remains unclear. HIE was induced by a permanent ligation of the right carotid artery, followed by an 8% O₂ hypoxic condition for 1 h. At 6 weeks of age, HIE mice were randomly assigned to either standard cages or EE cages. In the behavioral assessments, EE mice showed significantly improved motor performances in rotarod tests, ladder walking tests, and hanging wire tests, compared with HIE control mice. EE mice also significantly enhanced cognitive performances in Y-maze tests. Particularly, EE mice showed a significant increase in Ca_v 2.1 (P/Q type) and presynaptic proteins by molecular assessments, and a significant increase of Ca_v 2.1 in histological assessments of the cerebral cortex and hippocampus. These results indicate that EE can upregulate the expression of the Ca_v 2.1 channel and presynaptic proteins related to the synaptic vesicle cycle and neurotransmitter release, which may be responsible for motor and cognitive improvements in HIE.