Current Organizations / Institutes

The organizations/institutes from the scholar's latest article

Previous Organizations / Institutes

The organizations / institutes from the scholar's other articles in the past ten years


Kate S. Early has a total of 40 co-authors. Here are the top co-authors by number of shared publications:


Latest Publications

  • Applying the jigsaw learning method to structural kinesiology

    by Kate S. Early, Josie Williams, William A. Saltarelli

    The jigsaw learning approach divides complex anatomical concepts into manageable subtopics for students to learn in small groups. This method then fosters collaborative learning and peer teaching to communicate subtopics to others, putting together the whole puzzle of a concept. By assuming dual roles as learners and teachers, students develop critical thinking, communication, and teamwork skills. We provide a detailed framework for implementing jigsaw learning in undergraduate structural kinesiology courses.


  • Open Access

    Personalized Hydration Strategy to Improve Fluid Balance and Intermittent Exercise Performance in the Heat

    by Haicheng Li, Kate S. Early, Guangxia Zhang, Pengwei Ma, Haoyan Wang

    Sweat rate and electrolyte losses have a large inter-individual variability. A personalized approach to hydration can overcome this issue to meet an individual’s needs. This study aimed to investigate the effects of a personalized hydration strategy (PHS) on fluid balance and intermittent exercise performance. Twelve participants conducted 11 laboratory visits including a VO2max test and two 5-day trial arms under normothermic (NOR) or hyperthermic (HYP) environmental conditions. Each arm began with three days of familiarization exercise followed by two random exercise trials with either a PHS or a control (CON). Then, participants crossed over to the second arm for: NOR+PHS, NOR+CON, HYP+PHS, or HYP+CON. The PHS was prescribed according to the participants’ fluid and sweat sodium losses. CON drank ad libitum of commercially-available electrolyte solution. Exercise trials consisted of two phases: (1) 45 min constant workload; (2) high-intensity intermittent exercise (HIIT) until exhaustion. Fluids were only provided in phase 1. PHS had a significantly greater fluid intake (HYP+PHS: 831.7 ± 166.4 g; NOR+PHS: 734.2 ± 144.9 g) compared to CON (HYP+CON: 369.8 ± 221.7 g; NOR+CON: 272.3 ± 143.0 g), regardless of environmental conditions (p < 0.001). HYP+CON produced the lowest sweat sodium concentration (56.2 ± 9.0 mmol/L) compared to other trials (p < 0.001). HYP+PHS had a slower elevated thirst perception and a longer HIIT (765 ± 452 s) compared to HYP+CON (548 ± 283 s, p = 0.04). Thus, PHS reinforces fluid intake and successfully optimizes hydration status, regardless of environmental conditions. PHS may be or is an important factor in preventing negative physiological consequences during high-intensity exercise in the heat.


  • Open Access

    Personalized Hydration Strategy Improved Fluid Balance and Intermittent Exercise Performance In The Heat

    by Haicheng Li, Kate S. Early, Guangxia Zhang, Pengwei Ma, Haoyan Wang

    Sweat rate and electrolyte losses have a large inter-individual variability, a personalized approach to hydration can overcome this issue to meet an individual’s needs. This study aimed to investigate the effects of personalized hydration strategy (PHS) on fluid balance and intermittent exercise performance. Twelve participants conducted 11 laboratory visits including a VO2max test and two 5-day trial arms under normothermic (NOR) or hyperthermic (HYP) environmental conditions. Each arm began with 3-day of familiarization exercise following by two random exercise trials with a either PHS or control (CON). Then, participants crossed-over to the second arm for: NOR+PHS, NOR+CON, HYP+PHS, and HYP+CON. The PHS was prescribed according to participants’ fluid and sweat sodium losses. CON drank ad-libitum of commercially-available electrolyte solution. Exercise trials consisted of two phases: 1) 45min constant workload; 2) high-intensity intermittent exercise (HIIT) until exhaustion. PHS had a significantly greater fluid intake compared to CON. HYP+CON produced the lowest sweat sodium concentration. HYP+PHS had a lower thirst perception and a longer HIIT compared to HYP+CON. Thus, PHS reinforces fluid intake and successfully optimizes hydration status, regardless of environmental conditions. PHS may be or is an important factor to preventing negative physiological consequences during high-intensity exercise in the heat.


  • Open Access

    The Effect of Watermelon Juice Supplementation on Heart Rate Variability and Metabolic Response during an Oral Glucose Challenge: A Randomized, Double-Blind, Placebo-Controlled Crossover Trial

    by Rachel Matthews, Kate S. Early, Cullen M. Vincellette, Jack Losso, Guillaume Spielmann, Brian A. Irving, Timothy D. Allerton

    Heart rate variability (HRV) provides a simple method to evaluate autonomic function in health and disease. A reduction in HRV may indicate autonomic dysfunction and is strongly associated with aspects of cardiometabolic disease, including hyperglycemia. Reduced nitric oxide (NO) bioavailability is also implicated in the development of cardiometabolic disease and autonomic dysfunction. Watermelons are natural sources of L-arginine and L-citrulline, substrates used for NO synthesis. Watermelon consumption can improve NO bioavailability. We conducted a randomized, double-blind, placebo-controlled crossover trial to test the effects of 2 weeks of daily watermelon juice (WMJ) supplementation on HRV in response to an oral glucose challenge (OGC) in healthy young adults. We also performed indirect calorimetry to assess if our intervention altered the metabolic response to the OGC. WMJ supplementation preserved high-frequency power (HF) (treatment effect, p = 0.03) and the percentage of successive differences that differ by more than 50 ms (pNN50) (treatment effect, p = 0.009) when compared to the placebo treatment. There was no difference in resting energy expenditure or substate oxidation according to treatment. We report that WMJ supplementation attenuates OGC-induced reductions in HRV. Future work should emphasize the importance of NO bioavailability in autonomic dysfunction in cardiometabolic disease.


  • Open Access

    Positional Differences in Pre-Season Scrimmage Performance of Division I Collegiate Football Players

    by Kate S. Early, Nathan P. Lemoine, Annie Simoneaux, Shelly Mullenix, Jack Marucci, Michael J. MacLellan, Neil M. Johannsen

    This study aimed to describe the physical demands of American football players using novel performance analysis techniques. Heart rate (HR) and accelerometer-based activity levels were observed across two pre-season scrimmages in 23 Division I collegiate football players (age: 19 ± 1 y, height: 1.90 ± 0.06 m, weight: 116.2 ± 19.4 kg). Data were analyzed using a MATLAB program and inter-rater reproducibility assessed using inter-class correlations (ICC). Players were analyzed by side (offense/defense) and position (skill/non-skill). Performance variables assessed in bursts of activity included burst duration, HRmean and HRmax (bpm), and mean activity (vector magnitude units [vmu]). Exercise intensity was categorized as time spent in % HRmax in 5% increments. The burst duration (8.1±3.9 min, ICC = 0.72), HRmean (157 ± 12 bpm, ICC = 0.96) and mean activity (0.30 ± 0.05 vmu, ICC = 0.86) were reproducible. HRmean (p = 0.05) and HRmax (p = 0.001) were greater on defense. Offense spent more time at 65–70% HRmax (p = 0.01), 70–75% HRmax (p = 0.02) while defense spent more time 90–95% HRmax and ≥95% HRmax (p = 0.03). HRmean (p = 0.70) and HRpeak (p = 0.80) were not different between positions across both sides. Skilled players demonstrated greater mean activity (p = 0.02). The sport-specific analysis described HR and activity level in a reproducible manner. Automated methods of assessing HR may be useful in training and game time performance but ultimately provides support to coaching decision making.


  • EFFECT OF BLOOD FLOW RESTRICTION TRAINING ON MUSCULAR PERFORMANCE, PAIN AND VASCULAR FUNCTION

    by Kate S. Early, Mallory Rockhill, Alicia Bryan, Brian Tyo, David Buuck, Josh McGinty

    Blood flow restriction (BFR) training enhances muscular strength and hypertrophy in several populations including older adults and injured athletes. However, the efficacy of emerging BFR technologies on muscular adaptations, vascular health, and pain is unclear. The purpose of this study was to examine muscular performance, pain and vascular function in response to eight weeks of BFR compared to traditional resistance training and a control group. Randomized control trial Thirty-one overtly healthy participants (age: 23 ± 4y, 65% female) underwent eight weeks of supervised high load resistance training (RES), low load resistance training with BFR (BFR) or no training (control, CON). RES and BFR (with pneumatic bands) performed seven upper and lower body exercises, two to three sessions per week at 60% and 30% of one-repetition maximum (1RM), respectively. Twenty-four hours post-exercise, general muscle soreness was assessed via a visual analog scale (VAS) and present pain intensity (PPI) of the McGill Pain Questionnaire. At baseline and after eight weeks, participants underwent one-repetition maximum (1RM), and flow-mediated dilation (FMD) testing. At baseline all groups exhibited similar muscle strength and endurance and vascular function. At the end of training, RES and BFR groups significantly increased muscle strength (1RM) to a similar magnitude as compared to the CON group (p < 0.0001), but did not alter body composition. FMD significantly increased in RES and BFR groups compared to CON group (p = 0.006). VAS and PPI were similar between RES and BFR groups throughout the exercise sessions until VAS decreased in the BFR group after the last session compared to the RES group (p = 0.02). Compared to RES, BFR resulted in similar muscular performance (strength and endurance) and vascular improvements at a lower exercise intensity, suggesting BFR is an effective alternative to high load resistance training. Further longitudinal studies may gain greater understanding regarding general muscle pain and soreness when using BFR. Therapy, Level 2


  • Open Access

    Effects of Field Position on Fluid Balance and Electrolyte Losses in Collegiate Women’s Soccer Players

    by Haoyan Wang, Kate S. Early, Bailey M. Theall, Adam C. Lowe, Nathan P. Lemoine, Jack Marucci, Shelly Mullenix, Neil M. Johannsen

    Background and objectives: Research investigating hydration strategies specialized for women’s soccer players is limited, despite the growth in the sport. The purpose of this study was to determine the effects of fluid balance and electrolyte losses in collegiate women’s soccer players. Materials and Methods: Eighteen NCAA Division I women’s soccer players were recruited (age: 19.2 ± 1.0 yr; weight: 68.5 ± 9.0 kg, and height: 168.4 ± 6.7 cm; mean ± SD), including: 3 forwards (FW), 7 mid-fielders (MD), 5 defenders (DF), and 3 goalkeepers (GK). Players practiced outdoor during spring off-season training camp for a total 14 practices (WBGT: 18.3 ± 3.1 °C). The main outcome measures included body mass change (BMC), sweat rate, urine and sweat electrolyte concentrations, and fluid intake. Results: Results were analyzed for comparison between low (LOW; 16.2 ± 2.6° C, n = 7) and moderate risk environments for hyperthermia (MOD; 20.5 ± 1.5 °C, n = 7) as well as by field position. The majority (54%) of players were in a hypohydrated state prior to practice. Overall, 26.7% of players had a %BMC greater than 0%, 71.4% of players had a %BMC less than −2%, and 1.9% of players had a %BMC greater than −2% (all MD position). Mean %BMC and sweat rate in all environmental conditions were −0.4 ± 0.4 kg (−0.5 ± 0.6% body mass) and 1.03 ± 0.21 mg·cm−2·min−1, respectively. In the MOD environment, players exhibited a greater sweat rate (1.07 ± 0.22 mg·cm−2·min−1) compared to LOW (0.99 ± 0.22 mg·cm−2·min−1; p = 0.02). By position, DF had a greater total fluid intake and a lower %BMC compared to FW, MD, and GK (all p < 0.001). FW had a greater sweat sodium (Na+) (51.4 ± 9.8 mmol·L−1), whereas GK had the lowest sweat sodium (Na+) (30.9 ± 3.9 mmol·L−1). Conclusions: Hydration strategies should target pre-practice to ensure players are adequately hydrated. Environments deemed to be of moderate risk of hyperthermia significantly elevated the sweat rate but did not influence fluid intake and hydration status compared to low-risk environments. Given the differences in fluid balance and sweat responses, recommendations should be issued relative to soccer position.


  • Open Access

    Free-living, continuous hypo-hydration, and cardiovascular response to exercise in a heated environment

    by Kate S. Early, Conrad P. Earnest, Bailey Theall, Nathan P. Lemoine, Brian Harrell, Neil M. Johannsen

    Chronic dehydration (DEH) and heat stress combined with poor cardiovascular (CV) health may influence physiological responses to exercise. We examined the effects of free‐living induced hypo‐hydration on physiological responses to exercise in a heated environment and whether resting CV health is related to these changes. Participants (N = 16, 20.6 ± 1.2 years) were randomized to 3 days of voluntary fluid restriction (DEH) or intake (hydration [HYD]) followed by an exercise bout. CV health was assessed by flow‐mediated dilation (FMD), pulse wave analysis, and heart rate variability (HRV). HYD was assessed by weight, urine color, and specific gravity (USG). Exercise trials were conducted in a heated environment (30.3 ± 0.8°C, 27.4 ± 7.4% RH) on a cycle ergometer for 30 min. Heart rate (HR), weighted skin (Tsk) and mean body temperature (Tb) and skin blood flow (SBF) were assessed during exercise. Pre‐exercise weight (P < 0.005), urine color, and USG (P < 0.001) were different in between trials. HR was greater in DEH (153 ± 26 bpm) versus HYD (144 ± 23 bpm, P = 0.02) after exercise. No group differences were found, but a time interaction P < 0.001) for all temperature responses and time‐by‐trial interaction for Tre (P < 0.01) and Tsk (P < 0.001) was observed. Greater changes in Tre (P = 0.02) and Tsk (P < 0.01) were associated with increased FMD. Free‐living, continuous DEH alters weight, blood, and urine markers of HYD as well as HR response during exercise. Resting CV health was related to increased change in Tre and Tsk, suggesting CV health plays a role in the mechanism of heat dissipation when DEH even in college‐age men and women.


  • Impact Of Progressive, Chronic Dehydration On Cardiovascular Responses To Exercise In A Heated Environment

    by Kate S. Early, Bailey Theall, Nathan Lemoine, Brian Harrell, Conrad P. Earnest, Neil M. Johannsen

  • The Effects of Exercise Training on Brachial Artery Flow-Mediated Dilation

    by Kate S. Early, Abigail Stewart, Neil Johannsen, Carl J. Lavie, Jerry R. Thomas, Michael Welsch

    PURPOSE: Flow-mediated dilation, a barometer of cardiovascular (CV) health, is reported to increase with exercise training (ET); however, the potential moderating factors of ET are not clear to date. The purpose of this study was to determine the effect of ET assessed by brachial artery flow-mediated dilation (BAFMD). METHODS: Authors searched PubMed between January 1999 and December 2013, bibliographies, and reviews to identify studies examining ET and BAFMD. Two independent reviewers extracted quality, descriptive, exercise, and outcome data of eligible studies. Data were presented as weighted effect sizes (ESs) and 95% confidence limits. RESULTS: Analysis included 66 studies reporting BAFMD data (1865 ET and 635 control subjects). Overall, ET had significant improvements in BAFMD compared with controls (P < .0001). Exercise training at higher ET intensities resulted in a greater increase in BAFMD (9.29; 95% CI, 5.09-13.47) than lower ET intensities (3.63; 95% CI, −0.56 to 7.83) or control (−0.42; 95% CI, −2.06 to 1.21). Subjects whose ET duration was ≥150 min/wk (11.33; 95% CI, 7.15-15.51) had a significant improvement in BAFMD compared with those with P = .11) and baseline artery diameter (P = .31) did not modify the BAFMD response to ET. CONCLUSION: Exercise training contributes to a significant increase in BAFMD. These results provide indirect evidence that ET alters a well-known factor associated with the primary and secondary prevention of CV diseases. Exercise training interventions, including greater intensity and duration, may optimize the increase in BAFMD.