Brian Vala Nahed
Current Organizations / Institutes
The organizations/institutes from the scholar's latest article
Previous Organizations / Institutes
The organizations / institutes from the scholar's other articles in the past ten years
Brian Vala Nahed has a total of 831 co-authors. Here are the top co-authors by number of shared publications:
- William T. Curry
Department of Neurosurgery, Massachusetts General Hospital, Boston, MA
52 shared publications - Daniel P. Cahill
Department of Neurosurgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
46 shared publications - Brian P. Walcott
Department of Neurosurgery, Massachusetts General Hospital, Harvard Medical School, 55 Fruit Street, White Building Room 502, Boston, MA 02114, USA
41 shared publications - Bob S. Carter
Department of Neurosurgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
38 shared publications Ganesh M. Shankar
24 shared publications- Leonora Balaj
Department of Neurosurgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
24 shared publications
Latest Publications
- 11 September 2026
- Published by Wolters Kluwer Health in Neurosurgery
Automated Case Logging for Surgical Residency Training Using the Electronic Health Record: A Pilot Study
BACKGROUND AND OBJECTIVES: Case logging is essential for competency-based evaluation in residency but requires manual entry, which is susceptible to error, leading to delayed submission and underreporting. We present a novel, fully automated electronic health record (EHR)–integrated platform that extracts data from clinical documentation and logs it into the Accreditation Council for Graduate Medical Education (ACGME) case log system. We aim to evaluate the feasibility and effectiveness of an automated EHR extraction and case-logging system linked to the ACGME. METHODS: We evaluated case logs from 20 residents (post-graduate year 1-7) at an academic neurosurgery department from June to September 2025. Automated case logs were extracted from our digital EHR data warehouse, current procedural terminology codes were mapped to procedure code IDs, and residents verified automated logs before ACGME transmission. Manual case logs were extracted from operative reports in Epic by 2 staff members for comparison. Accuracy, precision, and sensitivity were assessed by comparing automated logs against manual logs. Time savings was estimated by comparing manual and automated per case-logging time across clinical residency years. RESULTS: A total of 1977 cases were automatically pulled compared with 2041 cases pulled from manual chart review. After review by each resident, 1955 of the automatically pulled cases were correctly logged and categorized when compared with manual cases (94.8% accuracy), with a 98.9% precision and 95.8% sensitivity. Traditional self-reported case logging took, on average, 199.9 ± 99.1 seconds per case. In comparison, reviewing and confirming automated case logs required an average of 68.4 ± 75.1 seconds per case. Per ACGME case minimums, automated logging reduced time by 66%, saving a neurosurgical resident 58 hours over the course of 5 operative, clinical years. CONCLUSION: Automated case logs provide an accurate, time-effective tool that can reduce administrative burden. Future studies should evaluate how to further improve and broaden the application of automated case logs to other specialties.
- 11 September 2026
- Published by Wolters Kluwer Health in Neurosurgery
Automated Case Logging for Surgical Residency Training Using the Electronic Health Record: A Pilot Study
BACKGROUND AND OBJECTIVES: Case logging is essential for competency-based evaluation in residency but requires manual entry, which is susceptible to error, leading to delayed submission and underreporting. We present a novel, fully automated electronic health record (EHR)–integrated platform that extracts data from clinical documentation and logs it into the Accreditation Council for Graduate Medical Education (ACGME) case log system. We aim to evaluate the feasibility and effectiveness of an automated EHR extraction and case-logging system linked to the ACGME. METHODS: We evaluated case logs from 20 residents (post-graduate year 1-7) at an academic neurosurgery department from June to September 2025. Automated case logs were extracted from our digital EHR data warehouse, current procedural terminology codes were mapped to procedure code IDs, and residents verified automated logs before ACGME transmission. Manual case logs were extracted from operative reports in Epic by 2 staff members for comparison. Accuracy, precision, and sensitivity were assessed by comparing automated logs against manual logs. Time savings was estimated by comparing manual and automated per case-logging time across clinical residency years. RESULTS: A total of 1977 cases were automatically pulled compared with 2041 cases pulled from manual chart review. After review by each resident, 1955 of the automatically pulled cases were correctly logged and categorized when compared with manual cases (94.8% accuracy), with a 98.9% precision and 95.8% sensitivity. Traditional self-reported case logging took, on average, 199.9 ± 99.1 seconds per case. In comparison, reviewing and confirming automated case logs required an average of 68.4 ± 75.1 seconds per case. Per ACGME case minimums, automated logging reduced time by 66%, saving a neurosurgical resident 58 hours over the course of 5 operative, clinical years. CONCLUSION: Automated case logs provide an accurate, time-effective tool that can reduce administrative burden. Future studies should evaluate how to further improve and broaden the application of automated case logs to other specialties.
- Open Access
- 14 August 2026
- Published by American Association for Cancer Research (AACR)
Supplementary Table S2 from Dose Escalation with Intensity-Modulated Proton Therapy for Patients with High-Risk Meningiomas – Results from a Phase I Trial
Study Representativeness Table.
- 14 August 2026
- Published by American Association for Cancer Research (AACR)
Open AccessSupplementary Table S2 from Dose Escalation with Intensity-Modulated Proton Therapy for Patients with High-Risk Meningiomas – Results from a Phase I Trial
Study Representativeness Table.
- Open Access
- 14 August 2026
- Published by American Association for Cancer Research (AACR)
Supplementary Data S1 from Dose Escalation with Intensity-Modulated Proton Therapy for Patients with High-Risk Meningiomas – Results from a Phase I Trial
Organs at risk dose constraints.
- 14 August 2026
- Published by American Association for Cancer Research (AACR)
Open AccessSupplementary Data S1 from Dose Escalation with Intensity-Modulated Proton Therapy for Patients with High-Risk Meningiomas – Results from a Phase I Trial
Organs at risk dose constraints.
- Open Access
- 14 August 2026
- Published by American Association for Cancer Research (AACR)
Data from Dose Escalation with Intensity-Modulated Proton Therapy for Patients with High-Risk Meningiomas – Results from a Phase I Trial
Purpose:Outcomes for grade 2 and 3 meningiomas are poor. A few studies suggest a benefit from radiotherapy dose escalation. This trial evaluates the safety and efficacy of dose escalation with intensity-modulated proton therapy (IMPT) for grade 2 and 3 meningiomas. Patients and Methods:This prospective single-arm phase I trial enrolled patients with grade 2 meningioma with residual disease or recurrence or patients with grade 3 meningioma after gross total resection. Patients underwent dose-escalated IMPT to 66 Gy relative biological effectiveness [Gy(RBE)] for grade 2 gross disease and 63 Gy(RBE) for grade 3 tumor beds. The primary endpoint was acute dose-limiting toxicity (DLT). Secondary endpoints included progression-free survival (PFS), overall survival (OS), and late toxicity. Results:Twenty-one patients with 16 grade 2 and 5 grade 3 meningiomas were enrolled and treated between 2016 and 2023. The median clinical and radiographic follow-up periods were 3.4 and 3.2 years, respectively. No DLT was observed. Five new late grade 3 toxicities occurred in four patients. Three treatment failures were observed in two grade 2 and one grade 3 tumors. Two deaths occurred in patients with grade 2 meningiomas. The 1-, 2-, and 3-year PFS rates were 100%, 95%, and 88.2%, respectively. The corresponding OS rates were 100%, 95%, and 95%, respectively. Conclusions:This first prospective trial investigating dose-escalated IMPT for high-grade meningiomas demonstrated a favorable early safety profile and clinical outcomes. Phase II and III studies are warranted to confirm the superiority of dose escalation for high-grade meningiomas.
- 14 August 2026
- Published by American Association for Cancer Research (AACR)
Open AccessData from Dose Escalation with Intensity-Modulated Proton Therapy for Patients with High-Risk Meningiomas – Results from a Phase I Trial
Purpose:Outcomes for grade 2 and 3 meningiomas are poor. A few studies suggest a benefit from radiotherapy dose escalation. This trial evaluates the safety and efficacy of dose escalation with intensity-modulated proton therapy (IMPT) for grade 2 and 3 meningiomas. Patients and Methods:This prospective single-arm phase I trial enrolled patients with grade 2 meningioma with residual disease or recurrence or patients with grade 3 meningioma after gross total resection. Patients underwent dose-escalated IMPT to 66 Gy relative biological effectiveness [Gy(RBE)] for grade 2 gross disease and 63 Gy(RBE) for grade 3 tumor beds. The primary endpoint was acute dose-limiting toxicity (DLT). Secondary endpoints included progression-free survival (PFS), overall survival (OS), and late toxicity. Results:Twenty-one patients with 16 grade 2 and 5 grade 3 meningiomas were enrolled and treated between 2016 and 2023. The median clinical and radiographic follow-up periods were 3.4 and 3.2 years, respectively. No DLT was observed. Five new late grade 3 toxicities occurred in four patients. Three treatment failures were observed in two grade 2 and one grade 3 tumors. Two deaths occurred in patients with grade 2 meningiomas. The 1-, 2-, and 3-year PFS rates were 100%, 95%, and 88.2%, respectively. The corresponding OS rates were 100%, 95%, and 95%, respectively. Conclusions:This first prospective trial investigating dose-escalated IMPT for high-grade meningiomas demonstrated a favorable early safety profile and clinical outcomes. Phase II and III studies are warranted to confirm the superiority of dose escalation for high-grade meningiomas.
- Open Access
- 14 August 2026
- Published by American Association for Cancer Research (AACR)
Supplementary Figure S1 from Dose Escalation with Intensity-Modulated Proton Therapy for Patients with High-Risk Meningiomas – Results from a Phase I Trial
Overall survival. A: Complete cohort. B: Stratified by WHO grading. C: Stratified by treatment indication.
- 14 August 2026
- Published by American Association for Cancer Research (AACR)
Open AccessSupplementary Figure S1 from Dose Escalation with Intensity-Modulated Proton Therapy for Patients with High-Risk Meningiomas – Results from a Phase I Trial
Overall survival. A: Complete cohort. B: Stratified by WHO grading. C: Stratified by treatment indication.
- Open Access
- 14 August 2026
- Published by American Association for Cancer Research (AACR)
Supplementary Table S1 from Dose Escalation with Intensity-Modulated Proton Therapy for Patients with High-Risk Meningiomas – Results from a Phase I Trial
Local failure rates, progression-free survival, and overall survival.
- 14 August 2026
- Published by American Association for Cancer Research (AACR)
Open AccessSupplementary Table S1 from Dose Escalation with Intensity-Modulated Proton Therapy for Patients with High-Risk Meningiomas – Results from a Phase I Trial
Local failure rates, progression-free survival, and overall survival.
- 18 May 2026
- Published by American Association for Cancer Research (AACR) in Clinical Cancer Research
- Vol. 32 (16) , 3552-3560
Dose Escalation With Intensity-Modulated Proton Therapy for Patients with High-Risk Meningiomas – Results From a Phase 1 Trial
Background: Outcomes for grade 2 and 3 meningiomas are poor. A few studies suggest a benefit from radiation therapy dose escalation. This trial evaluates the safety and efficacy of dose escalation with intensity-modulated proton therapy (IMPT) for grade 2 and 3 meningiomas. Methods: This prospective single-arm phase 1 trial enrolled patients with grade 2 meningioma with residual disease or recurrence, or patients with grade 3 meningioma after gross total resection. Patients underwent dose-escalated IMPT to 66 Gy (relative biological effectiveness, RBE) for grade 2 gross disease and 63 Gy(RBE) for grade 3 tumor beds. The primary endpoint was acute dose-limiting toxicity (DLT). Secondary endpoints included progression-free survival (PFS), overall survival (OS), and late toxicity. Results: Twenty-one patients with 16 grade 2 and five grade 3 meningiomas were enrolled and treated between 2016 and 2023. The median clinical and radiographic follow-up periods were 3.4 and 3.2 years, respectively. No DLT was observed. Five new late grade 3 toxicities occurred in four patients. Three treatment failures were observed in two grade 2 and one grade 3 tumors. Two deaths occurred in patients with grade 2 meningiomas. The 1-, 2-, and 3-year PFS rates were 100%, 95.0%, and 88.2%, respectively. The corresponding OS rates were 100%, 95.0%, and 95.0%, respectively. Conclusions: This first prospective trial investigating dose-escalated IMPT for high-grade meningiomas demonstrated a favorable early safety profile and clinical outcomes. Phase 2 and 3 studies are warranted to confirm the superiority of dose escalation for high-grade meningiomas.
- 18 May 2026
- Published by American Association for Cancer Research (AACR) in Clinical Cancer Research
- Vol. 32 (16) , 3552-3560
Dose Escalation With Intensity-Modulated Proton Therapy for Patients with High-Risk Meningiomas – Results From a Phase 1 Trial
Background: Outcomes for grade 2 and 3 meningiomas are poor. A few studies suggest a benefit from radiation therapy dose escalation. This trial evaluates the safety and efficacy of dose escalation with intensity-modulated proton therapy (IMPT) for grade 2 and 3 meningiomas. Methods: This prospective single-arm phase 1 trial enrolled patients with grade 2 meningioma with residual disease or recurrence, or patients with grade 3 meningioma after gross total resection. Patients underwent dose-escalated IMPT to 66 Gy (relative biological effectiveness, RBE) for grade 2 gross disease and 63 Gy(RBE) for grade 3 tumor beds. The primary endpoint was acute dose-limiting toxicity (DLT). Secondary endpoints included progression-free survival (PFS), overall survival (OS), and late toxicity. Results: Twenty-one patients with 16 grade 2 and five grade 3 meningiomas were enrolled and treated between 2016 and 2023. The median clinical and radiographic follow-up periods were 3.4 and 3.2 years, respectively. No DLT was observed. Five new late grade 3 toxicities occurred in four patients. Three treatment failures were observed in two grade 2 and one grade 3 tumors. Two deaths occurred in patients with grade 2 meningiomas. The 1-, 2-, and 3-year PFS rates were 100%, 95.0%, and 88.2%, respectively. The corresponding OS rates were 100%, 95.0%, and 95.0%, respectively. Conclusions: This first prospective trial investigating dose-escalated IMPT for high-grade meningiomas demonstrated a favorable early safety profile and clinical outcomes. Phase 2 and 3 studies are warranted to confirm the superiority of dose escalation for high-grade meningiomas.
- Open Access
- 1 October 2025
- Published by Elsevier in World Neurosurgery
- Vol. 204, 124524
An International Course on Intraoperative Ultrasound in Neurosurgery: Evaluation of a Multicenter, Hands-On Course in Promoting Familiarity and Use of Intraoperative Ultrasound in Neurosurgery
- 1 October 2025
- Published by Elsevier in World Neurosurgery
- Vol. 204, 124524
Open AccessAn International Course on Intraoperative Ultrasound in Neurosurgery: Evaluation of a Multicenter, Hands-On Course in Promoting Familiarity and Use of Intraoperative Ultrasound in Neurosurgery
- 4 September 2025
- Published by Elsevier in Journal of Clinical Neuroscience
- Vol. 141, 111612
Early exposure to neurosurgery: promoting early specialty interest through a single-day resident-driven neurosurgical course for preclinical students
- 4 September 2025
- Published by Elsevier in Journal of Clinical Neuroscience
- Vol. 141, 111612
Early exposure to neurosurgery: promoting early specialty interest through a single-day resident-driven neurosurgical course for preclinical students
- Open Access
- 4 July 2025
- Published by Elsevier in World Neurosurgery
- Vol. 201, 124257
Neurosurgical Resident Skill Development Using a Novel Simulator-Based Anterior Cervical Discectomy and Fusion Curriculum
- 4 July 2025
- Published by Elsevier in World Neurosurgery
- Vol. 201, 124257
Open AccessNeurosurgical Resident Skill Development Using a Novel Simulator-Based Anterior Cervical Discectomy and Fusion Curriculum