Ho-Kyung Ha
Current Organizations / Institutes
The organizations/institutes from the scholar's latest article
Research Subjects
Ho-Kyung Ha has a total of 30 co-authors. Here are the top co-authors by number of shared publications:
- Won-Jae Lee
Division of Applied Life Science Gyeongsang National University Jinju Korea
10 shared publications - Mee-Ryung Lee
Department of Food and Nutrition Daegu University Gyeongsan Korea
7 shared publications - Chang-Ki Huh
Department of Food Science and Technology, Sunchon National University, Suncheon 57922, Republic of Korea
5 shared publications - Imkyung Oh
Department of Food Science and Technology, Sunchon National University, Suncheon 57922, Republic of Korea
5 shared publications - Jungsil Kim
Department of Smart Bio-Industrial Mechanical Engineering, College of Agriculture and Life Sciences, Kyungpook National University, Daegu, Republic of Korea
3 shared publications - Lola Ayu Istifiani
Department of Nutrition, Faculty of Health Sciences, Brawijaya University, Malang, Indonesia
3 shared publications
Latest Publications
- Open Access
- 11 February 2026
- Published by MDPI AG in Applied Sciences
- Vol. 16 (4) , 1801
Fermentation with Lactic Acid Bacteria Enhances the Anti-Inflammatory Activity of Ginseng Sprout Extract in RAW 264.7 Macrophages
Perennial ginseng (Panax ginseng) has long been valued for its medicinal properties. However, ginseng sprouts are gaining prominence as a versatile food source due to the high levels of bioactive compounds in their leaves and stems. To further enhance their functional value, this study investigated the effects of fermentation using lactic acid bacteria, specifically Lactobacillus and Enterococcus strains, on the antioxidant and anti-inflammatory potential of ginseng sprout extract (GSE). Chemical analyses revealed that fermentation significantly increased total phenolic content (TPC) and ginsenoside Rb1 levels, which were associated with enhanced radical-scavenging activity and superoxide dismutase (SOD)-like activity. In lipopolysaccharide (LPS)-stimulated RAW 264.7 macrophages, fermented GSE (FGSE) exhibited significantly greater anti-inflammatory effects than non-fermented GSE. This enhancement was evidenced by marked downregulation of pro-inflammatory mediators, including nitric oxide (NO) and prostaglandin E2 (PGE2), along with their corresponding enzymes, inducible nitric oxide synthase (iNOS) and cyclooxygenase-2 (COX-2). Notably, the anti-inflammatory profile of FGSE was distinguished by its ability to suppress specific cytokines that were not significantly affected by GSE. Although both GSE and FGSE attenuated interleukin-1beta (IL-1β) and interleukin-6 (IL-6), only FGSE achieved statistically significant inhibition of tumor necrosis factor-alpha (TNF-α) and monocyte chemoattractant protein-1 (MCP-1). These findings indicate that fermentation is a critical process for surpassing the efficacy threshold of GSE against key inflammatory signals. Overall, the enrichment of bioactive metabolites during fermentation suggests that FGSE can serve as a potent functional ingredient for modulating inflammatory responses, with considerable potential for the development of advanced functional foods.
- 11 February 2026
- Published by MDPI AG in Applied Sciences
- Vol. 16 (4) , 1801
Open AccessFermentation with Lactic Acid Bacteria Enhances the Anti-Inflammatory Activity of Ginseng Sprout Extract in RAW 264.7 Macrophages
Perennial ginseng (Panax ginseng) has long been valued for its medicinal properties. However, ginseng sprouts are gaining prominence as a versatile food source due to the high levels of bioactive compounds in their leaves and stems. To further enhance their functional value, this study investigated the effects of fermentation using lactic acid bacteria, specifically Lactobacillus and Enterococcus strains, on the antioxidant and anti-inflammatory potential of ginseng sprout extract (GSE). Chemical analyses revealed that fermentation significantly increased total phenolic content (TPC) and ginsenoside Rb1 levels, which were associated with enhanced radical-scavenging activity and superoxide dismutase (SOD)-like activity. In lipopolysaccharide (LPS)-stimulated RAW 264.7 macrophages, fermented GSE (FGSE) exhibited significantly greater anti-inflammatory effects than non-fermented GSE. This enhancement was evidenced by marked downregulation of pro-inflammatory mediators, including nitric oxide (NO) and prostaglandin E2 (PGE2), along with their corresponding enzymes, inducible nitric oxide synthase (iNOS) and cyclooxygenase-2 (COX-2). Notably, the anti-inflammatory profile of FGSE was distinguished by its ability to suppress specific cytokines that were not significantly affected by GSE. Although both GSE and FGSE attenuated interleukin-1beta (IL-1β) and interleukin-6 (IL-6), only FGSE achieved statistically significant inhibition of tumor necrosis factor-alpha (TNF-α) and monocyte chemoattractant protein-1 (MCP-1). These findings indicate that fermentation is a critical process for surpassing the efficacy threshold of GSE against key inflammatory signals. Overall, the enrichment of bioactive metabolites during fermentation suggests that FGSE can serve as a potent functional ingredient for modulating inflammatory responses, with considerable potential for the development of advanced functional foods.
- Open Access
Development of an Emulsion Gel Containing Peanut Sprout Oil as a Fat Replacer in Muffins: Physicochemical, Tomographic, and Texture Properties
Peanut sprouts are known to increase their resveratrol content during germination, leading to cultivation in smart farms. Recently, peanut sprout oil extraction and sales have gained traction; however, processed foods utilizing peanut sprout oil have yet to be developed. In this study, water-in-oil (W/O) emulsion gels were structured with water, peanut sprout oil (PSO), sorbitan monostearate (SMS), and candelilla wax (CW) in different ratios, and their potential as shortening substitutes in muffins was evaluated on physicochemical and sensory properties. PSO comprised 67% unsaturated fatty acids and had higher phospholipid (17.97%) and resveratrol (15.95 µg/L) contents and antioxidant activity (71.52%) compared to peanut oil. The PSO emulsion gels were physically structured without changing their chemical compositions. The SMS and CW ratios were found to have a significant influence on the textural properties, solid fat content, rheology, and crystallization of the emulsion gels. The viscoelastic properties of the emulsion gels showed a higher storage modulus than loss modulus and increased with increasing gelator content. Muffins prepared with emulsion gels were characterized by a harder texture and larger pore size, while in the case of muffins mixed with a ratio of 25% SMS and 75% CW, there was no significant difference in overall preference of sensory evaluation compared to shortening muffins. Thus, these findings reveal the potential utility of PSO as a fat substitute and indicate that W/O emulsion gels are suitable for producing muffins without a loss of quality.
Open AccessDevelopment of an Emulsion Gel Containing Peanut Sprout Oil as a Fat Replacer in Muffins: Physicochemical, Tomographic, and Texture Properties
Peanut sprouts are known to increase their resveratrol content during germination, leading to cultivation in smart farms. Recently, peanut sprout oil extraction and sales have gained traction; however, processed foods utilizing peanut sprout oil have yet to be developed. In this study, water-in-oil (W/O) emulsion gels were structured with water, peanut sprout oil (PSO), sorbitan monostearate (SMS), and candelilla wax (CW) in different ratios, and their potential as shortening substitutes in muffins was evaluated on physicochemical and sensory properties. PSO comprised 67% unsaturated fatty acids and had higher phospholipid (17.97%) and resveratrol (15.95 µg/L) contents and antioxidant activity (71.52%) compared to peanut oil. The PSO emulsion gels were physically structured without changing their chemical compositions. The SMS and CW ratios were found to have a significant influence on the textural properties, solid fat content, rheology, and crystallization of the emulsion gels. The viscoelastic properties of the emulsion gels showed a higher storage modulus than loss modulus and increased with increasing gelator content. Muffins prepared with emulsion gels were characterized by a harder texture and larger pore size, while in the case of muffins mixed with a ratio of 25% SMS and 75% CW, there was no significant difference in overall preference of sensory evaluation compared to shortening muffins. Thus, these findings reveal the potential utility of PSO as a fat substitute and indicate that W/O emulsion gels are suitable for producing muffins without a loss of quality.
- Open Access
- 30 April 2023
- Published by The Korean Society of Food Preservation in Korean Journal of Food Preservation
- Vol. 30 (2) , 272-286
Quality characteristics of different parts of garlic sprouts produced by smart farms during growth
- 30 April 2023
- Published by The Korean Society of Food Preservation in Korean Journal of Food Preservation
- Vol. 30 (2) , 272-286
Open AccessQuality characteristics of different parts of garlic sprouts produced by smart farms during growth
- Open Access
- 1 March 2023
- Published by Springer Nature in Food Science of Animal Resources
- Vol. 43 (2) , 220-231
Development of Hydrophobically Modified Casein Derivative-Based Delivery System for Docosahexaenoic Acids by an Acid-Induced Gelation
Food Science of Animal Resources (Food Sci. Anim. Resour.) is an international, peer-reviewed bimonthly journal publishing original research and reviews on basic and applied aspects of the use of animal resources including the meat, egg, dairy, and edible insect/worm products. Food Sci. Anim. Resour. is published and distributed by the Korean Society for Food Science of Animal Resources.
- 1 March 2023
- Published by Springer Nature in Food Science of Animal Resources
- Vol. 43 (2) , 220-231
Open AccessDevelopment of Hydrophobically Modified Casein Derivative-Based Delivery System for Docosahexaenoic Acids by an Acid-Induced Gelation
Food Science of Animal Resources (Food Sci. Anim. Resour.) is an international, peer-reviewed bimonthly journal publishing original research and reviews on basic and applied aspects of the use of animal resources including the meat, egg, dairy, and edible insect/worm products. Food Sci. Anim. Resour. is published and distributed by the Korean Society for Food Science of Animal Resources.
- Open Access
- 30 April 2022
- Published by The Korean Society of Food Preservation in Korean Journal of Food Preservation
- Vol. 29 (2) , 263-275
Quality characteristics of yakju added with lactic acid bacteria-fermented ginseng sprouts
This study aimed to improve the physiological activity and processing properties of ginseng sprouts. We first determined the effect of extraction and fermentation conditions on the antioxidant activity of ginseng sprouts. The optimal extraction conditions were 2 h at 80°C, with water as a solvent. The fermentation strains used were Lactobacillus delbrueckii subsp. bulgaricus KCTC 3635 and Enterococcus faecalis KCTC 3206. We then analyzed the changes in the reducing sugar and alcohol content. In fermented samples, the reducing sugar content was lower and the alcohol content was higher than those in control sample. The cell counts of lactic acid bacteria were higher in the fermented samples than those in the control sample. Fermented samples contained more ginsenoside than the extract samples, and ginsenoside was not detected in the control sample. The total polyphenol and total flavonoid contents were relatively high in the fermented samples, particularly in the sample fermented by E. faecalis. Finally, sensory evaluation revealed that the Yakju prepared using ginseng sprouts fermented by lactic acid bacteria was preferable to other drinks control and ginseng sprouts extracted sample. Overall, it was confirme that the addition of fermented ginseng improved the physiological activity and palatability of yakju, there by improving the quality of yakju.
- 30 April 2022
- Published by The Korean Society of Food Preservation in Korean Journal of Food Preservation
- Vol. 29 (2) , 263-275
Open AccessQuality characteristics of yakju added with lactic acid bacteria-fermented ginseng sprouts
This study aimed to improve the physiological activity and processing properties of ginseng sprouts. We first determined the effect of extraction and fermentation conditions on the antioxidant activity of ginseng sprouts. The optimal extraction conditions were 2 h at 80°C, with water as a solvent. The fermentation strains used were Lactobacillus delbrueckii subsp. bulgaricus KCTC 3635 and Enterococcus faecalis KCTC 3206. We then analyzed the changes in the reducing sugar and alcohol content. In fermented samples, the reducing sugar content was lower and the alcohol content was higher than those in control sample. The cell counts of lactic acid bacteria were higher in the fermented samples than those in the control sample. Fermented samples contained more ginsenoside than the extract samples, and ginsenoside was not detected in the control sample. The total polyphenol and total flavonoid contents were relatively high in the fermented samples, particularly in the sample fermented by E. faecalis. Finally, sensory evaluation revealed that the Yakju prepared using ginseng sprouts fermented by lactic acid bacteria was preferable to other drinks control and ginseng sprouts extracted sample. Overall, it was confirme that the addition of fermented ginseng improved the physiological activity and palatability of yakju, there by improving the quality of yakju.
- Open Access
- 31 December 2021
- Published by Korean Society of Milk Science and Biotechnology in Journal of Dairy Science and Biotechnology
- Vol. 39 (4) , 157-165
Suitability of Hot Water Extract from Panax ginseng Sprout Powder as a Dairy Additive
Journal of Dairy Science and Biotechnology (J. Dairy Sci. Biotechnol., ISSN 2384-0269; eISSN 2508-3635) publishes original papers or review articles covering topics of chemistry, biotechnology, processing and microbiology of milk and milk products since 1981
- 31 December 2021
- Published by Korean Society of Milk Science and Biotechnology in Journal of Dairy Science and Biotechnology
- Vol. 39 (4) , 157-165
Open AccessSuitability of Hot Water Extract from Panax ginseng Sprout Powder as a Dairy Additive
Journal of Dairy Science and Biotechnology (J. Dairy Sci. Biotechnol., ISSN 2384-0269; eISSN 2508-3635) publishes original papers or review articles covering topics of chemistry, biotechnology, processing and microbiology of milk and milk products since 1981
- Open Access
- 30 September 2021
- Published by Korean Society of Animal Science and Technology in Journal of Animal Science and Technology
- Vol. 63 (5) , 1182-1193
Development and evaluation of probiotic delivery systems using the rennet-induced gelation of milk proteins
Journal of Animal Science and Technology (JAST) is a peer-reviewed, open access journal publishing original research, review articles and notes in all fields of animal science. Topics covered by the journal include: genetics and breeding, physiology, nutrition of monogastric animals, nutrition of ruminants, animal products (milk, meat, eggs and their by-products) and their processing, grasslands and roughages, livestock environment, animal biotechnology, animal behavior and welfare.
- 30 September 2021
- Published by Korean Society of Animal Science and Technology in Journal of Animal Science and Technology
- Vol. 63 (5) , 1182-1193
Open AccessDevelopment and evaluation of probiotic delivery systems using the rennet-induced gelation of milk proteins
Journal of Animal Science and Technology (JAST) is a peer-reviewed, open access journal publishing original research, review articles and notes in all fields of animal science. Topics covered by the journal include: genetics and breeding, physiology, nutrition of monogastric animals, nutrition of ruminants, animal products (milk, meat, eggs and their by-products) and their processing, grasslands and roughages, livestock environment, animal biotechnology, animal behavior and welfare.
- Open Access
- 1 September 2021
- Published by Springer Nature in Food Science of Animal Resources
- Vol. 41 (5) , 894-904
Encapsulation of Lactobacillus rhamnosus GG Using Milk Protein-Based Delivery Systems: Effects of Reaction Temperature and Holding Time on Their Physicochemical and Functional Properties
Food Science of Animal Resources (Food Sci. Anim. Resour.) is an international, peer-reviewed bimonthly journal publishing original research and reviews on basic and applied aspects of the use of animal resources including the meat, egg, dairy, and edible insect/worm products. Food Sci. Anim. Resour. is published and distributed by the Korean Society for Food Science of Animal Resources.
- 1 September 2021
- Published by Springer Nature in Food Science of Animal Resources
- Vol. 41 (5) , 894-904
Open AccessEncapsulation of Lactobacillus rhamnosus GG Using Milk Protein-Based Delivery Systems: Effects of Reaction Temperature and Holding Time on Their Physicochemical and Functional Properties
Food Science of Animal Resources (Food Sci. Anim. Resour.) is an international, peer-reviewed bimonthly journal publishing original research and reviews on basic and applied aspects of the use of animal resources including the meat, egg, dairy, and edible insect/worm products. Food Sci. Anim. Resour. is published and distributed by the Korean Society for Food Science of Animal Resources.
- Open Access
- 31 March 2021
- Published by Korean Society of Milk Science and Biotechnology in Journal of Dairy Science and Biotechnology
- Vol. 39 (1) , 27-35
Application of Casein Phosphopeptide/Chitosan Oligosaccharide Nanocomplex to Dairy Foods
Journal of Dairy Science and Biotechnology (J. Dairy Sci. Biotechnol., ISSN 2384-0269; eISSN 2508-3635) publishes original papers or review articles covering topics of chemistry, biotechnology, processing and microbiology of milk and milk products since 1981
- 31 March 2021
- Published by Korean Society of Milk Science and Biotechnology in Journal of Dairy Science and Biotechnology
- Vol. 39 (1) , 27-35
Open AccessApplication of Casein Phosphopeptide/Chitosan Oligosaccharide Nanocomplex to Dairy Foods
Journal of Dairy Science and Biotechnology (J. Dairy Sci. Biotechnol., ISSN 2384-0269; eISSN 2508-3635) publishes original papers or review articles covering topics of chemistry, biotechnology, processing and microbiology of milk and milk products since 1981
- Open Access
- 31 December 2020
- Published by Korean Society of Milk Science and Biotechnology in Journal of Dairy Science and Biotechnology
- Vol. 38 (4) , 189-196
Milk Protein-Stabilized Emulsion Delivery System and Its Application to Foods
Journal of Dairy Science and Biotechnology (J. Dairy Sci. Biotechnol., ISSN 2384-0269; eISSN 2508-3635) publishes original papers or review articles covering topics of chemistry, biotechnology, processing and microbiology of milk and milk products since 1981
- 31 December 2020
- Published by Korean Society of Milk Science and Biotechnology in Journal of Dairy Science and Biotechnology
- Vol. 38 (4) , 189-196
Open AccessMilk Protein-Stabilized Emulsion Delivery System and Its Application to Foods
Journal of Dairy Science and Biotechnology (J. Dairy Sci. Biotechnol., ISSN 2384-0269; eISSN 2508-3635) publishes original papers or review articles covering topics of chemistry, biotechnology, processing and microbiology of milk and milk products since 1981