İsmail Basmacı

Objective: This study aimed to investigate the association between the preoperative albumin-to-globulin ratio (AGR) and pathological stage and tumor grade in patients who underwent transurethral resection of bladder tumor (TURBT) for primary bladder tumors.Materials and Methods: A total of 153 patients who underwent transurethral resection of bladder tumor (TURBT) for primary urothelial carcinoma between March 2017 and February 2020 were included in the study. AGR was calculated using preoperative serum albumin and total protein levels. Among the exclusion criteria were active infection, autoimmune disease, hepatic disease, and concomitant malignancy. The optimal AGR cut-off value was determined using receiver operating characteristic (ROC) curve analysis and the Youden index. Independent predictors of pathological stage (NMIBC/MIBC) and tumor grade (low/high Grade) were evaluated using logistic regression analysis.Results: The median age of the patients was 68 years (IQR: 59–75), and 88.9% were male. The pathological stage distribution was Ta in 39.9%, T1 in 39.9%, and T2 in 20.3% of patients, while tumor grade distribution was low Grade in 54.2% and high Grade in 43.1%. The median AGR value of the cohort was 1.32 (IQR: 1.17–1.50). AGR was significantly lower in both the MIBC group (p = 0.003) and the high-grade group (p < 0.001) compared to their respective counterparts. ROC analysis identified an optimal cut-off value of 1.35 for both clinical outcomes (AUC=0.649, 95% CI: 0.542–0.755 for MIBC and AUC=0.656, 95% CI: 0.568–0.744 for high-grade disease). In multivariate logistic regression analysis, AGR was independently associated with both MIBC (OR=0.16, 95% CI: 0.03–0.97; p = 0.046) and high-grade disease (OR=0.18, 95% CI: 0.04–0.74; p = 0.018).Conclusion: Preoperative AGR is independently associated with pathological stage and tumor grade in primary bladder tumors. The ability to calculate this parameter from routine biochemical tests without additional cost makes it clinically valuable for preoperative risk stratification. Further validation of these findings in larger patient cohorts is warranted.

Purpose Erectile dysfunction (ED) is a worldwide health problem. Oral phosphodiesterase type 5 inhibitors (PDE5I) are used in its first-line treatment. This study aimed to compare the effects of hyperbaric oxygen (HBO) treatment with PDE5I treatment and determine the patient-dependent factors affecting the efficacy of the HBO treatment and duration of action of HBO treatment. Methods Adult male patients who presented to the HBO unit for HBO treatment with non-urological indications and had ED based on the International Index for Erectile Function (IIEF-5) constituted the target population of this study. Participants were given HBO treatment (Group 1), no treatment (Group 2), or daily oral tadalafil 5 mg treatment (Group 3). The treatment duration was 1 month. Patients were assessed by IIEF-5 both initially and after the completion of 1 month. Results There were significant increases in the mean IIEF-5 scores of the patients in Group 1 and Group 3 (p < 0.001, p < 0.001). However, there was no significant improvement in Group 2 (p = 0.496). Also, the post-treatment IIEF-5 scores of Group 1 and Group 3 were significantly higher than Group 2 (p < 0.001). There was no significant difference between the IIEF-5 scores and ∆IIEF-5 values of Group 1 and Group 3 (p = 0.166, p = 0.093). Evaluation regarding comorbidities revealed that patients with the peripheral vascular disease did not improve with HBO treatment (p = 0.285). Conclusion HBO can improve erectile functions, and it can be a reasonable alternative for patients who cannot use PDE5Is due to comorbidities or treatment side effects.

Lenfatik Sistem Anatomisi Mustafa Cenk YILMAZ Lenfatik Sistem Histolojisi Semih TAN Emine TURAL Lenfatik Sistem Genel Tanı Bölümleri ve Fizyolojisi Itır Ebru ZEMHERİ Pınar Engin Zerk Lenf Bezi Biyokimyası Zerrin KUTLU Lenf Bezinin Büyüme Nedenleri Eren ALTUN Lenfadenopatilerde Anamnez ve Fizik Muayene Bulguları Emine KIZILAY Açıklanamayan Lenfadenopati: Değerlendirme ve Ayırıcı Tanı Çağlayan KEKLİKKIRAN Lenfadenopati Sebebinin Belirlenmesi İçin İpuçları ve İlk Testler Ömer TOPDAĞI Ateş ve Lenfadenopati Ahmet Cem YARDIMCI Esra FERSAN Lenfatik Sıstemi Etkileyen İnfeksiyonlar Esra FERSAN Ahmet Cem YARDIMCI Lenf Bezi Travmaları Doğukan ÖZDEMİR Lenf Nodu Görüntülemesi Önder TURNA Lenf Nodu Sitopatolojisi Fatma Seher PEHLİVAN Kanser Tedavisi Sonrası Lenfödem Burak ERDEMCİ Baş ve Boyun Lenfadenopatileri Sami Engin MUZ Mehmet Nuri ELGÖRMÜŞ Aksiller Lenfadenopati Yeliz YILMAZ BOZOK İnguinal Lenfadenopatilere Yaklaşım Emir ÇAPKINOĞLU Yaygın Lenfadenopati Fatma KESMEZ CAN Lenfadenopatiye Yaklaşım Süleyman BAŞ Pınar Zehra DAVARCI Sentinel Lenf Nodu Biyopsisi Osman ERDOĞAN Gastrointestinal Sistem Kanserlerinde Lenf Nodu Metastazı Selçuk GÜLMEZ Sentinel Lenf Nodu Sintigrafisi Ayşe Esra ARSLAN Non-Hodgkin Lenfomada Radyoterapi Halil Cumhur YILDIRIM Servikal Lenf Nodlarında Açık Biyopsi Endikasyonları ve Boyun Diseksiyonları Nihal EFE ATİLA Servikal Lap ve Aıds Orçun BARKAY Servikal Lap Yapan Granülomatöz Hastalıklar Umut Devrim BİNAY Servikal Lenfadenopati Yapan Fungal Hastalıklar Işıl Deniz ALIRAVCI Sevil ALKAN ÇEVİKER Servikal Lenfadenopati Yapan Nonenfeksiyöz Enflamatuar İdyopatik Hastalıklar Dursun Mehmet MEHEL Mehmet ÇELEBİ Primeri Bilinmeyen Servikal Metastatik Lenfadenopatiler Dursun Mehmet MEHEL Mehmet ÇELEBİ Lenf Metastazının Moleküler ve Hücresel Değişkenleri Sevgi KARABULUT UZUNÇAKMAK Mediastinal Lenfadenopatiler Canan GÜNDÜZ GÜRKAN Hodgkin Lenfomada Radyoterapi İpek Pınar ARAL Gülhan GÜLER AVCI Lenfadenopatilere Ürolojik Maligniteler Açısından Yaklaşım İsmail BASMACI Non Hodgkın Lenfoma Hematolojik Yaklaşım İbrahim EKER Hodgkin Lenfoma Funda PEPEDİL TANRIKULU Nurhilal BÜYÜKKURT Şüpheli Lenf Nodlarının Çıkartılmasında Roll Tekniği ve Radyokılavuzlu İşlemlerde Radyasyondan Korunma Aslı AYAN

SUMMARY OBJECTIVES To prospectively investigate the alterations and normal ranges of ureteral jet dynamics after double-J-stent (DJS) removal in patients who underwent renal transplantation (RTx). METHODS Patients who underwent RTx were prospectively evaluated between November 2017 and June 2018. After RTx, Doppler ultrasonography (D-US) was performed on all patients after DJS removal. Renal artery resistive index (RA-Ri), renal pelvis anterior-posterior diameter (RP-APD), pelvicalyceal system dilation (PCSD), and ureteral jet flow dynamics (maximum and average velocity; JETmax and JETave) were measured by D-US. Also, patients’ demographics, estimated glomerular filtration rate (eGFR) levels, and acute rejection were investigated in the study. Patients were assessed two different times by D-US, about 6 and 12 weeks after DJS removal, and the two different measurements were compared with the Wilcoxon test and Chi-square test. RESULTS A total of 25 patients were evaluated in the study. Nonobstructive PCSD rate (12% vs 8%), JETave (18.8 vs 12.9 cm/sec), and JETmax (29.2 vs 20 cm/sec) levels were significantly decreased (p values are 0.01, 0.010 and 0.014, respectively). In addition, monophasic and square pattern rates were significantly observed to increase over time (p=0.035); however, ureteral jet patterns were correlated between the two different D-US measurements (R=0.225, p=0.032). CONCLUSION After RTx, dilation rate and ureteral jet flow velocities were significantly decreased, and monophasic and square JETpattern rates were significantly increased over time. Ureteral jet dynamics can provide useful information about the follow-up of peristaltic activity in the pelvic-ureteric system.

İnguinal mesane herniasyonu nadir olmakla birlikte tüm inguinal hernili olguların %1-4’ünde görülmektedir. Üreterin inguinal herniasyonu ise daha nadir bir durumdur ve literatürde 2009 yılına kadar yaklaşık 140 olgu bildirilmiştir. Bu yazıda solda daha belirgin olmak üzere her iki skrotal bölgesinde şişlik nedenli kliniğimize başvuran hastaya konan mesane ve üreter herniasyonu olgusu sunulmuş olup literatür eşliğinde tartışılmaktadır.

To evaluate the predictive value of attenuation value (HU) in renal pelvis urine for detecting renal pelvis urine culture (RPUC) positivity in obstructed urinary systems.