Dongtao Lu
Current Organizations / Institutes
The organizations/institutes from the scholar's latest article
Research Subjects
Dongtao Lu has a total of 9 co-authors. Here are the top co-authors by number of shared publications:
- Baofeng Yu
School of Basic Medicine, Basic Medical Science Center; Shanxi Key Laboratory of Metabolic-Immune Homeostasis and Drug Innovation, Shanxi Medical University, No. 55 Wenhua Street, Jinzhong, 030600, China.
1 shared publication - Cheng Yang
College of Chemistry Institute of Nuclear Science and Technology Key Laboratory of Radiation Physics and Technology of Ministry of Education Sichuan University Chengdu China
1 shared publication - Chuan Dong
Environmental Science Research Institute, Shanxi University, Taiyuan 030006, China
1 shared publication - Shaomin Shuang
School of Chemistry and Chemical Engineering, Shanxi University, Taiyuan, China
1 shared publication - Tao Gong
Department of Biochemistry and Molecular Biology, School of Basic Medical Science, Shanxi Medical University, Taiyuan 030001, China
1 shared publication - Wenting Liang
Institute of Environmental Science, College of Chemistry and Chemical Engineering, Shanxi University, Taiyuan, China
1 shared publication
Latest Publications
- Open Access
β-Cyclodextrin–Hyaluronic Acid Polymer Functionalized Magnetic Graphene Oxide Nanocomposites for Targeted Photo-Chemotherapy of Tumor Cells
A multifunctional targeted drug delivery platform (CDHA–MGO) has been successfully constructed by grafting β-cyclodextrin–hyaluronic acid polymers (CDHA) to Fe3O4–graphene oxide (MGO). The obtained CDHA–MGO nanocomposite has good water-dispersibility, easy magnetic separation, high near-infrared (NIR) photothermal heating, and excellent biocompatibility. The β-cyclodextrin-hyaluronic acid polymers efficaciously enhance the doxorubicin (DOX) loading amount up to 485.43 mg·g−1. Meanwhile, the Fe3O4–graphene oxide provides a facile photothermal response mechanism to handle the NIR-triggered release of DOX in weak acidic solvent environments. Significantly, the DOX-loaded nanocomposite (DOX@CDHA–MGO) has displayed CD44 receptor-mediated active targeting recognition and chemo-photothermal synergistic therapy of hepatoma cells. These findings suggest that the as-prepared drug delivery platform would be of valuable potential for cancer-targeted photo-chemotherapy.
Open Accessβ-Cyclodextrin–Hyaluronic Acid Polymer Functionalized Magnetic Graphene Oxide Nanocomposites for Targeted Photo-Chemotherapy of Tumor Cells
A multifunctional targeted drug delivery platform (CDHA–MGO) has been successfully constructed by grafting β-cyclodextrin–hyaluronic acid polymers (CDHA) to Fe3O4–graphene oxide (MGO). The obtained CDHA–MGO nanocomposite has good water-dispersibility, easy magnetic separation, high near-infrared (NIR) photothermal heating, and excellent biocompatibility. The β-cyclodextrin-hyaluronic acid polymers efficaciously enhance the doxorubicin (DOX) loading amount up to 485.43 mg·g−1. Meanwhile, the Fe3O4–graphene oxide provides a facile photothermal response mechanism to handle the NIR-triggered release of DOX in weak acidic solvent environments. Significantly, the DOX-loaded nanocomposite (DOX@CDHA–MGO) has displayed CD44 receptor-mediated active targeting recognition and chemo-photothermal synergistic therapy of hepatoma cells. These findings suggest that the as-prepared drug delivery platform would be of valuable potential for cancer-targeted photo-chemotherapy.