Achim Hoerauf
Current Organizations / Institutes
The organizations/institutes from the scholar's latest article
Research Subjects
Research Interests
Achim Hoerauf has a total of 13 co-authors. Here are the top co-authors by number of shared publications:
- Che Julius Ngwa
Division of Cellular and Applied Infection Biology, RWTH Aachen University, Aachen, Germany
2 shared publications - Mathias Eyong Esum
Research Foundation for Tropical Diseases and the Environment (REFOTDE), Buea, Cameroon; Parasite and Vector Research Unit (PAVRU), Department of Microbiology and Parasitology, University of Buea, Buea, Cameroon
2 shared publications - Nicholas Tendongfor
Faculty of Health Sciences, University of Buea, Buea P.O. Box 63, Cameroon
2 shared publications - Peter Enyong
Research Foundation for Tropical Diseases and Environment, P.O. Box 474, Buea, Cameroon
2 shared publications - Samuel Wanji
Parasites and Vector Biology research unit (PAVBRU), Department of Microbiology and Parasitology, University of Buea, Buea, Cameroon
2 shared publications - Armand Seraphin Nkwescheu
Cameroon Society of Epidemiology, Yaounde P.O. Box 1411, Cameroon
1 shared publication
Latest Publications
- Open Access
- 21 February 2012
- Published by Springer Nature in Parasites & Vectors
- Vol. 5 (1) , 43
The human parasite Loa loa in cytokine and cytokine receptor gene knock out BALB/c mice: survival, development and localization
Immunological mechanisms involved in the survival and development of human filarial species in the vertebrate host are poorly known due to the lack of suitable experimental models. In order to understand the role of cytokines in the survival and development of filarial larvae in the vertebrate host, we infected different strains of BALB/c mice deficient in a number of cytokine or cytokine receptor genes with Loa loa. The survival and development of larvae were monitored.
- 21 February 2012
- Published by Springer Nature in Parasites & Vectors
- Vol. 5 (1) , 43
Open AccessThe human parasite Loa loa in cytokine and cytokine receptor gene knock out BALB/c mice: survival, development and localization
Immunological mechanisms involved in the survival and development of human filarial species in the vertebrate host are poorly known due to the lack of suitable experimental models. In order to understand the role of cytokines in the survival and development of filarial larvae in the vertebrate host, we infected different strains of BALB/c mice deficient in a number of cytokine or cytokine receptor genes with Loa loa. The survival and development of larvae were monitored.
- Open Access
- 1 January 2009
- Published by Springer Nature in Parasites & Vectors
- Vol. 2 (1) , 39
Community-directed delivery of doxycycline for the treatment of onchocerciasis in areas of co-endemicity with loiasis in Cameroon
Severe side effects following ivermectin treatment of onchocerciasis in areas of co-endemicity with loaisis have been an impediment for the work of the African Programme for Onchocerciasis Control (APOC) in forested regions of several countries. Doxycycline has been shown to be effective in the treatment of onchocerciasis and has the added advantages of killing adult Onchocerca volvulus but neither adult Loa loa nor their microfilariae. This drug therefore offers great potential for the treatment of onchocerciasis in areas of co-endemicity with loiasis. The limitation of use of this drug is the duration of treatment that may pose a potential problem with therapeutic coverage and compliance with treatment. To benefit from the advantages that doxycycline offers in the treatment of onchocerciasis, it will be necessary to establish an effective distribution system that can access remote communities. This study assessed the feasibility of a large-scale distribution of doxycycline for the treatment of onchocerciasis in areas of co-endemicity with loiasis using a community-directed approach.
- 1 January 2009
- Published by Springer Nature in Parasites & Vectors
- Vol. 2 (1) , 39
Open AccessCommunity-directed delivery of doxycycline for the treatment of onchocerciasis in areas of co-endemicity with loiasis in Cameroon
Severe side effects following ivermectin treatment of onchocerciasis in areas of co-endemicity with loaisis have been an impediment for the work of the African Programme for Onchocerciasis Control (APOC) in forested regions of several countries. Doxycycline has been shown to be effective in the treatment of onchocerciasis and has the added advantages of killing adult Onchocerca volvulus but neither adult Loa loa nor their microfilariae. This drug therefore offers great potential for the treatment of onchocerciasis in areas of co-endemicity with loiasis. The limitation of use of this drug is the duration of treatment that may pose a potential problem with therapeutic coverage and compliance with treatment. To benefit from the advantages that doxycycline offers in the treatment of onchocerciasis, it will be necessary to establish an effective distribution system that can access remote communities. This study assessed the feasibility of a large-scale distribution of doxycycline for the treatment of onchocerciasis in areas of co-endemicity with loiasis using a community-directed approach.