Ka Zhang
Current Organizations / Institutes
The organizations/institutes from the scholar's latest article
Research Subjects
Ka Zhang has a total of 6 co-authors. Here are the top co-authors by number of shared publications:
- Lei Ye
Division of Pure and Applied Biochemistry, Department of Chemistry, Lund University, Lund, Sweden
2 shared publications - Leif Bülow
Lund University
2 shared publications - Cedric Dicko
Pure and Applied Biochemistry, Department of Chemistry, Lund University, Lund, Sweden
1 shared publication Haiyue Gong
Division of Pure and Applied Biochemistry, Department of Chemistry, Lund University, Box 124, 221 00 Lund, Sweden
1 shared publicationKarin Kettisen
Division of Pure and Applied Biochemistry, Department of Chemistry, Lund University, Box 124, 22100 Lund, Sweden
1 shared publicationTongchang Zhou
Division of Pure and Applied Biochemistry, Department of Chemistry, Lund University, Box 124, 22100 Lund, Sweden
1 shared publication
Latest Publications
- Open Access
- 21 February 2019
- Published by American Chemical Society (ACS) in ACS Applied Nano Materials
- Vol. 2 (3) , 1655-1663
Ag–Polymer Nanocomposites for Capture, Detection, and Destruction of Bacteria
Bacterial infection is one of the major problems for human health. To prevent outbreak of bacteria-caused diseases, early diagnosis of bacterial pathogen and effective destruction of pathogenic microorganisms are in urgent need. In this work, we developed a new multifunctional nanocomposite material that can effectively capture and destroy bacteria. Epoxide-modified nanoparticles were synthesized by micro-emulsion polymerization and precipitation polymerization. The epoxide groups on the particle surface were reacted with polyethyleneimine to introduce cationic amine groups. The amine groups on the nanoparticle surface enhanced the colloidal stability of the particles’ suspension, and provided multivalent interactions to bind and destroy the bacteria. After further modification with Ag nanoparticles, the final composite nanomaterial was able to not only capture and destroy Gram-negative bacteria, but also allow the bacteria’s fingerprint spectra to be obtained through surface-enhanced Raman scattering. The multifunctional nanoparticles developed in this work offer a new approach towards fast capture, detection and destruction of pathogenic bacteria.
- 21 February 2019
- Published by American Chemical Society (ACS) in ACS Applied Nano Materials
- Vol. 2 (3) , 1655-1663
Open AccessAg–Polymer Nanocomposites for Capture, Detection, and Destruction of Bacteria
Bacterial infection is one of the major problems for human health. To prevent outbreak of bacteria-caused diseases, early diagnosis of bacterial pathogen and effective destruction of pathogenic microorganisms are in urgent need. In this work, we developed a new multifunctional nanocomposite material that can effectively capture and destroy bacteria. Epoxide-modified nanoparticles were synthesized by micro-emulsion polymerization and precipitation polymerization. The epoxide groups on the particle surface were reacted with polyethyleneimine to introduce cationic amine groups. The amine groups on the nanoparticle surface enhanced the colloidal stability of the particles’ suspension, and provided multivalent interactions to bind and destroy the bacteria. After further modification with Ag nanoparticles, the final composite nanomaterial was able to not only capture and destroy Gram-negative bacteria, but also allow the bacteria’s fingerprint spectra to be obtained through surface-enhanced Raman scattering. The multifunctional nanoparticles developed in this work offer a new approach towards fast capture, detection and destruction of pathogenic bacteria.