John D. Haley

Supplementary Figure S4 shows immunohistochemical analyses of tumor cell and microenvironmental features in high-fat diet-fed mice.

Supplementary Figure S5 shows dietary remodeling of pancreatic lipid metabolism and phospholipid composition.

Supplementary Figure S2 shows dietary and physiologic measurements of female mice in the high-fat diet screen.

Supplementary Figure S3 shows fat mass and glucose homeostasis measurements in mice fed high-fat diets differing in oleic acid abundance.

Supplementary Figure S8 shows that excess dietary polyunsaturated fatty acids suppress tumorigenesis by altering lipid oxidation and ferroptosis sensitivity.

Supplementary Figure S6 shows dietary and plasma fatty acid correlations with disease burden in male KC mice.

Supplementary Figure S7 shows that dietary fatty acids remodel pancreatic phospholipids to perturb lipid peroxidation and ferroptosis sensitivity.

Supplementary Table S1 shows data on worldwide macronutrient availability and PDAC risk.

Supplementary Table S2 shows mouse diet panel ingredients.

Supplementary Table S4 shows RNA-seq analyses of high-fat diet-fed mice.