Ankita Gumaste
Current Organizations / Institutes
The organizations/institutes from the scholar's latest article
Research Subjects
Research Interests
Ankita Gumaste has a total of 5 co-authors. Here are the top co-authors by number of shared publications:
- Douglas Rioux
Department of Molecular, Cellular and Developmental Biology, Yale University, New Haven, United States
1 shared publication - J Sebastian Chahda
Department of Molecular, Cellular and Developmental Biology, Yale University, New Haven, United States
1 shared publication - Jennifer S. Sun
Department of Biochemistry and Microbiology, Rutgers University
1 shared publication - John R. Carlson
Department of Molecular, Cellular and Developmental Biology, Yale University, New Haven, CT, USA
1 shared publication - Nikki K Larter
Department of Molecular, Cellular and Developmental Biology, Yale University, New Haven, United States
1 shared publication
Latest Publications
- Open Access
- 19 September 2018
- Published by eLife Sciences Publications, Ltd in eLife
- Vol. 7
Humidity response depends on the small soluble protein Obp59a in Drosophila
Hygrosensation is an essential sensory modality that is used to find sources of moisture. Hygroreception allows animals to avoid desiccation, an existential threat that is increasing with climate change. Humidity response, however, remains poorly understood. Here we find that humidity-detecting sensilla in the Drosophila antenna express and rely on a small protein, Obp59a. Mutants lacking this protein are defective in three hygrosensory behaviors, one operating over seconds, one over minutes, and one over hours. Remarkably, loss of Obp59a and humidity response leads to an increase in desiccation resistance. Obp59a is an exceptionally well-conserved, highly localized, and abundantly expressed member of a large family of secreted proteins. Antennal Obps have long been believed to transport hydrophobic odorants, and a role in hygroreception was unexpected. The results enhance our understanding of hygroreception, Obp function, and desiccation resistance, a process that is critical to insect survival.
- 19 September 2018
- Published by eLife Sciences Publications, Ltd in eLife
- Vol. 7
Open AccessHumidity response depends on the small soluble protein Obp59a in Drosophila
Hygrosensation is an essential sensory modality that is used to find sources of moisture. Hygroreception allows animals to avoid desiccation, an existential threat that is increasing with climate change. Humidity response, however, remains poorly understood. Here we find that humidity-detecting sensilla in the Drosophila antenna express and rely on a small protein, Obp59a. Mutants lacking this protein are defective in three hygrosensory behaviors, one operating over seconds, one over minutes, and one over hours. Remarkably, loss of Obp59a and humidity response leads to an increase in desiccation resistance. Obp59a is an exceptionally well-conserved, highly localized, and abundantly expressed member of a large family of secreted proteins. Antennal Obps have long been believed to transport hydrophobic odorants, and a role in hygroreception was unexpected. The results enhance our understanding of hygroreception, Obp function, and desiccation resistance, a process that is critical to insect survival.