Qianyue Wang
Current Organizations / Institutes
The organizations/institutes from the scholar's latest article
Research Subjects
Qianyue Wang has a total of 5 co-authors. Here are the top co-authors by number of shared publications:
- Chuanwei Yang
State Key Laboratory of Genetic Engineering, School of Life Sciences, Fudan University, Shanghai, China
1 shared publication - Lin Li
State Key Laboratory of Genetics and Development of Complex Phenotypes, Fudan University, Shanghai, China
1 shared publication - Qian Zhang
State Key Laboratory of Genetic Engineering, School of Life Sciences, Fudan University, Shanghai, China
1 shared publication - Xu Huang
Department of Biology, Duke University, Durham, USA
1 shared publication - Yupei Jiang
State Key Laboratory of Genetic Engineering, School of Life Sciences, Fudan University, Shanghai, China
1 shared publication
Latest Publications
- Open Access
- 21 June 2018
- Published by eLife Sciences Publications, Ltd in eLife
- Vol. 7
Shade-induced nuclear localization of PIF7 is regulated by phosphorylation and 14-3-3 proteins in Arabidopsis
Shade avoidance syndrome enables shaded plants to grow and compete effectively against their neighbors. In Arabidopsis, the shade-induced de-phosphorylation of the transcription factor PIF7 (PHYTOCHROME-INTERACTING FACTOR 7) is the key event linking light perception to stem elongation. However, the mechanism through which phosphorylation regulates the activity of PIF7 is unclear. Here, we show that shade light induces the de-phosphorylation and nuclear accumulation of PIF7. Phosphorylation-resistant site mutations in PIF7 result in increased nuclear localization and shade-induced gene expression, and consequently augment hypocotyl elongation. PIF7 interacts with 14-3-3 proteins. Blocking the interaction between PIF7 and 14-3-3 proteins or reducing the expression of 14-3-3 proteins accelerates shade-induced nuclear localization and de-phosphorylation of PIF7, and enhances the shade phenotype. By contrast, the 14-3-3 overexpressing line displays an attenuated shade phenotype. These studies demonstrate a phosphorylation-dependent translocation of PIF7 when plants are in shade and a novel mechanism involving 14-3-3 proteins, mediated by the retention of PIF7 in the cytoplasm that suppresses the shade response.
- 21 June 2018
- Published by eLife Sciences Publications, Ltd in eLife
- Vol. 7
Open AccessShade-induced nuclear localization of PIF7 is regulated by phosphorylation and 14-3-3 proteins in Arabidopsis
Shade avoidance syndrome enables shaded plants to grow and compete effectively against their neighbors. In Arabidopsis, the shade-induced de-phosphorylation of the transcription factor PIF7 (PHYTOCHROME-INTERACTING FACTOR 7) is the key event linking light perception to stem elongation. However, the mechanism through which phosphorylation regulates the activity of PIF7 is unclear. Here, we show that shade light induces the de-phosphorylation and nuclear accumulation of PIF7. Phosphorylation-resistant site mutations in PIF7 result in increased nuclear localization and shade-induced gene expression, and consequently augment hypocotyl elongation. PIF7 interacts with 14-3-3 proteins. Blocking the interaction between PIF7 and 14-3-3 proteins or reducing the expression of 14-3-3 proteins accelerates shade-induced nuclear localization and de-phosphorylation of PIF7, and enhances the shade phenotype. By contrast, the 14-3-3 overexpressing line displays an attenuated shade phenotype. These studies demonstrate a phosphorylation-dependent translocation of PIF7 when plants are in shade and a novel mechanism involving 14-3-3 proteins, mediated by the retention of PIF7 in the cytoplasm that suppresses the shade response.