Rui Xue
Research Subjects
Rui Xue has a total of 6 co-authors. Here are the top co-authors by number of shared publications:
- Hui Yu
Engineering Technology Research Center of Shanxi Province for Opto-electric Information and Instrument, Taiyuan 030051, China
1 shared publication - Kewu Li
School of Electrical and Control Engineering, North University of China, Taiyuan 030051, China
1 shared publication - Liming Wang
State Key Laboratory of Extreme Environment Optoelectronic Dynamic Measurement Technology and Instrument, North University of China, Taiyuan 030051, China
1 shared publication - Ning Jing
School of Information and Communication Engineering, North University of China 1 , Taiyuan 030051
1 shared publication - Shuang Wang
Engineering and Technology Research Center of Shanxi Province for Opto-Electric Information and Instrument, Taiyuan 030051, China
1 shared publication - Zhibin Wang
North University of China
1 shared publication
Latest Publications
- Open Access
Fast and Sensitive Ellipsometry-Based Biosensing
In this work, a biosensing method based on in situ, fast, and sensitive measurements of ellipsometric parameters (Ψ, ∆) is proposed. Bare silicon wafer substrate is functionalized and used to bind biomolecules in the solution. Coupled with a 45° dual-drive symmetric photoelastic modulator-based ellipsometry, the parameters Ψ and ∆ of biolayer arising due to biomolecular interactions are determined directly, and the refractive index (RI) of the solution and the effective thickness and surface mass density of the biolayer for various interaction time can be further monitored simultaneously. To illustrate the performance of the biosensing method, immunosensing for immunoglobulin G (IgG) was taken as a case study. The experiment results show that the biosensor response of the limit of detection for IgG is 15 ng/mL, and the data collection time is in milliseconds. Moreover, the method demonstrates a good specificity. Such technique is a promising candidate in developing a novel sensor which can realize fast and sensitive, label-free, easy operation, and cost-effective biosensing.
Open AccessFast and Sensitive Ellipsometry-Based Biosensing
In this work, a biosensing method based on in situ, fast, and sensitive measurements of ellipsometric parameters (Ψ, ∆) is proposed. Bare silicon wafer substrate is functionalized and used to bind biomolecules in the solution. Coupled with a 45° dual-drive symmetric photoelastic modulator-based ellipsometry, the parameters Ψ and ∆ of biolayer arising due to biomolecular interactions are determined directly, and the refractive index (RI) of the solution and the effective thickness and surface mass density of the biolayer for various interaction time can be further monitored simultaneously. To illustrate the performance of the biosensing method, immunosensing for immunoglobulin G (IgG) was taken as a case study. The experiment results show that the biosensor response of the limit of detection for IgG is 15 ng/mL, and the data collection time is in milliseconds. Moreover, the method demonstrates a good specificity. Such technique is a promising candidate in developing a novel sensor which can realize fast and sensitive, label-free, easy operation, and cost-effective biosensing.