Dee Lochmann
Current Organizations / Institutes
The organizations/institutes from the scholar's latest article
Research Subjects
Dee Lochmann has a total of 1 co-authors. Here are the top co-authors by number of shared publications:
Tara Richardson
Psychiatry and Behavioral Sciences, University of Kansas School of Medicine-Wichita, Wichita, KS, USA
1 shared publication
Latest Publications
- 1 January 2018
- Published by Springer Nature
- Vol. 250, 135-144
Selective Serotonin Reuptake Inhibitors
The first antidepressants were created by chance but brought the idea that central serotonin agonism produced an antidepressant effect. SSRIs were the first class of psychotropic medications to be rationally designed, meaning that researchers intended to utilize a specific mechanism of action while avoiding adverse effects. In this way, SSRIs were created to be safer and more tolerable than previous antidepressants. SSRIs share many similarities, but differ in terms of pharmacokinetics and effects on CYP450 enzymes, which is detailed in this chapter. Further information will be provided regarding safety, clinical indications/uses, and dosing recommendations.
- 1 January 2018
- Published by Springer Nature
- Vol. 250, 135-144
Selective Serotonin Reuptake Inhibitors
The first antidepressants were created by chance but brought the idea that central serotonin agonism produced an antidepressant effect. SSRIs were the first class of psychotropic medications to be rationally designed, meaning that researchers intended to utilize a specific mechanism of action while avoiding adverse effects. In this way, SSRIs were created to be safer and more tolerable than previous antidepressants. SSRIs share many similarities, but differ in terms of pharmacokinetics and effects on CYP450 enzymes, which is detailed in this chapter. Further information will be provided regarding safety, clinical indications/uses, and dosing recommendations.