Kuo-Chen Liao
Current Organizations / Institutes
The organizations/institutes from the scholar's latest article
Research Subjects
Kuo-Chen Liao has a total of 34 co-authors. Here are the top co-authors by number of shared publications:
Chang-Hsuan Peng
Chang Gung Medical Education Research Center, Chang Gung Memorial Hospital, Taoyuan, Taiwan
2 shared publications- Chang-Hsuan Peng
Chang Gung Medical Education Research Centre (CGMERC), CGMH Linkou Taiwan (ROC)
2 shared publications - Chien-Da Huang
Chang Gung Medical Education Research Centre (CG-MERC), Chang Gung Memorial Hospital, Linkou, Taiwan
2 shared publications Alenoush Saroyan
Department of Educational and Counselling Psychology, Faculty of Education, McGill University, Montreal, Canada
1 shared publication- Chang-Chyi Jenq
Chang Gung Medical Education Research Centre, Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Taipei, Taiwan
1 shared publication - Chao-Lien Liu
School of Medical Laboratory Science and Biotechnology, College of Medical Science and Technology, Taipei Medical University, Taipei, Taiwan; PhD Program in Medical Biotechnology, College of Medical Science and Technology, Taipei Medical University, Taipei, Taiwan
1 shared publication
Latest Publications
- Open Access
- 11 October 2026
- Published by Wiley in Medical Education
Treading the paths of guarding, guiding and growing: A positioning analysis of senior residents' identity constructions in clinical teaching activities
Introduction: Senior residents occupy a structurally peculiar position in clinical training: Simultaneously learners and teachers, they bear responsibility for both trainee development and patient safety. Although residents‐as‐teachers programmes have proliferated, most target technical skills rather than the identity work involved in becoming a clinical teacher. Little is known about what identities senior residents construct, or how , as they narrate their teaching experiences. Methods: Informed by positioning theory within a social constructionist paradigm, we conducted a discursive narrative inquiry using 23 longitudinal individual interviews with 14 purposively sampled senior internal medicine residents (R3–R4; nine female, five male) at a tertiary medical centre in northern Taiwan (2018–2021). Data analysis proceeded in two stages: thematic framework analysis to identify key narrative plotlines, followed by three‐level positioning analysis examining character trope construction within stories, between narrator and interviewer and in relation to broader societal discourses. Results: Three narrative plotlines organised senior residents' teaching stories: guarding , guiding and growing . Within these, 14 character tropes were identified, including experienced doctor, inexperienced teacher, guardian, guide and persistent learner. They were drawn upon fluidly and often simultaneously, revealing identity constructions that were dynamic and contextually contingent. Two overlapping socialisation transitions were visible across the data: From inexperienced trainee to experienced doctor and from experienced doctor to inexperienced teacher, each carrying emotional labour that institutional structures largely left unaddressed. Discussion: Senior residents' identity constructions are neither fixed nor unidirectional but continuously negotiated in the flow of clinical teaching interactions. Our findings expose an underexamined tension: The emotional and ethical burden of dual‐role navigation is routinely borne by individuals rather than absorbed by organisations. Residents‐as‐teachers programmes that attend only to technical competence risk missing this entirely. Fostering reflective identity work and distributing accountability for clinical supervision represent more productive directions.
- 11 October 2026
- Published by Wiley in Medical Education
Open AccessTreading the paths of guarding, guiding and growing: A positioning analysis of senior residents' identity constructions in clinical teaching activities
Introduction: Senior residents occupy a structurally peculiar position in clinical training: Simultaneously learners and teachers, they bear responsibility for both trainee development and patient safety. Although residents‐as‐teachers programmes have proliferated, most target technical skills rather than the identity work involved in becoming a clinical teacher. Little is known about what identities senior residents construct, or how , as they narrate their teaching experiences. Methods: Informed by positioning theory within a social constructionist paradigm, we conducted a discursive narrative inquiry using 23 longitudinal individual interviews with 14 purposively sampled senior internal medicine residents (R3–R4; nine female, five male) at a tertiary medical centre in northern Taiwan (2018–2021). Data analysis proceeded in two stages: thematic framework analysis to identify key narrative plotlines, followed by three‐level positioning analysis examining character trope construction within stories, between narrator and interviewer and in relation to broader societal discourses. Results: Three narrative plotlines organised senior residents' teaching stories: guarding , guiding and growing . Within these, 14 character tropes were identified, including experienced doctor, inexperienced teacher, guardian, guide and persistent learner. They were drawn upon fluidly and often simultaneously, revealing identity constructions that were dynamic and contextually contingent. Two overlapping socialisation transitions were visible across the data: From inexperienced trainee to experienced doctor and from experienced doctor to inexperienced teacher, each carrying emotional labour that institutional structures largely left unaddressed. Discussion: Senior residents' identity constructions are neither fixed nor unidirectional but continuously negotiated in the flow of clinical teaching interactions. Our findings expose an underexamined tension: The emotional and ethical burden of dual‐role navigation is routinely borne by individuals rather than absorbed by organisations. Residents‐as‐teachers programmes that attend only to technical competence risk missing this entirely. Fostering reflective identity work and distributing accountability for clinical supervision represent more productive directions.
- 18 August 2026
- Published by SAGE Publications in OMEGA - Journal of Death and Dying
Culturally Embedded, Gendered, and Iterative Grief Among Adult Sons Following Paternal Loss: A Qualitative Study
The death of a father is a major transition for adult sons, particularly in cultures emphasizing filial duty and masculine norms. This qualitative study explored how 24 bereaved sons in Chinese society experienced paternal loss using in-depth interviews and reflexive thematic analysis. Findings revealed a non-linear, iterative grieving process: sons assumed family responsibilities, maintained relational bonds, managed paradoxical emotions, reflected on father–son relationships, and engaged in recursive coping. Grief was culturally mediated, relational, and identity-transforming, highlighting the need for culturally sensitive support for bereaved adult sons.
- 18 August 2026
- Published by SAGE Publications in OMEGA - Journal of Death and Dying
Culturally Embedded, Gendered, and Iterative Grief Among Adult Sons Following Paternal Loss: A Qualitative Study
The death of a father is a major transition for adult sons, particularly in cultures emphasizing filial duty and masculine norms. This qualitative study explored how 24 bereaved sons in Chinese society experienced paternal loss using in-depth interviews and reflexive thematic analysis. Findings revealed a non-linear, iterative grieving process: sons assumed family responsibilities, maintained relational bonds, managed paradoxical emotions, reflected on father–son relationships, and engaged in recursive coping. Grief was culturally mediated, relational, and identity-transforming, highlighting the need for culturally sensitive support for bereaved adult sons.
- 21 April 2025
- Published by Wiley in Medical Education
- Vol. 59 (7) , 668-670
Defying or defining identity: Wrestling with the wicked problem of branding identities
Professional identity in medicine is fluid and complex. Liao comments on Branzetti et al. to outline how learners face identity struggles early, while seasoned physicians can use branding to sustain identity (if done authentically and ethically).
- 21 April 2025
- Published by Wiley in Medical Education
- Vol. 59 (7) , 668-670
Defying or defining identity: Wrestling with the wicked problem of branding identities
Professional identity in medicine is fluid and complex. Liao comments on Branzetti et al. to outline how learners face identity struggles early, while seasoned physicians can use branding to sustain identity (if done authentically and ethically).
- Open Access
- 9 January 2025
- Published by Ubiquity Press, Ltd. in Perspectives on Medical Education
- Vol. 14 (1) , 55-65
From Learner to Provider: Navigating Role Tensions in Postgraduate Medical Training Through Activity Theory
Introduction: The transition from medical school to residency, especially during the postgraduate year (PGY) internship, poses unique challenges as graduates navigate clinical practice complexities. Understanding PGYs’ experiences is crucial for developing effective support strategies to promote their professional growth and well-being. Methods: This qualitative, longitudinal study followed ten PGYs from August 2021 to July 2023, using biannual audio diary based on open-ended questions to capture their experiences. Data analysis, guided by Activity Theory, focused on role conflicts and contradictions as PGYs transitioned from learners to practicing physicians. Results: The analysis revealed prevalent role conflicts and contradictions, primarily due to the tension between the PGYs’ roles as learner and healthcare provider. Differences in objectives between PGYs and practicing doctors further exacerbated these conflicts, leading to clashes in priorities and care approaches. Consequently, PGYs experienced reality shock, lack of confidence, and feelings of incompetence, compounded by heavy workloads and exhaustion. These findings underscored the need for support and resources to help PGYs navigate these challenges and succeed in their healthcare roles. Discussions: Using Activity Theory to analyze the inherent challenges and contradictions within the PGY experience, this study offers insights for enhancing PGY preparedness, fostering both professional development and well-being. Drawing on recommendations supported by existing literature, which are stratified by tools, rules, and division of labor, we propose targeted strategies to address specific facets of the PGY role, thereby improving the overall training environment. This research highlights the need for tailored interventions to support PGYs through the challenging transition into clinical practice.
- 9 January 2025
- Published by Ubiquity Press, Ltd. in Perspectives on Medical Education
- Vol. 14 (1) , 55-65
Open AccessFrom Learner to Provider: Navigating Role Tensions in Postgraduate Medical Training Through Activity Theory
Introduction: The transition from medical school to residency, especially during the postgraduate year (PGY) internship, poses unique challenges as graduates navigate clinical practice complexities. Understanding PGYs’ experiences is crucial for developing effective support strategies to promote their professional growth and well-being. Methods: This qualitative, longitudinal study followed ten PGYs from August 2021 to July 2023, using biannual audio diary based on open-ended questions to capture their experiences. Data analysis, guided by Activity Theory, focused on role conflicts and contradictions as PGYs transitioned from learners to practicing physicians. Results: The analysis revealed prevalent role conflicts and contradictions, primarily due to the tension between the PGYs’ roles as learner and healthcare provider. Differences in objectives between PGYs and practicing doctors further exacerbated these conflicts, leading to clashes in priorities and care approaches. Consequently, PGYs experienced reality shock, lack of confidence, and feelings of incompetence, compounded by heavy workloads and exhaustion. These findings underscored the need for support and resources to help PGYs navigate these challenges and succeed in their healthcare roles. Discussions: Using Activity Theory to analyze the inherent challenges and contradictions within the PGY experience, this study offers insights for enhancing PGY preparedness, fostering both professional development and well-being. Drawing on recommendations supported by existing literature, which are stratified by tools, rules, and division of labor, we propose targeted strategies to address specific facets of the PGY role, thereby improving the overall training environment. This research highlights the need for tailored interventions to support PGYs through the challenging transition into clinical practice.
- 24 April 2023
- Published by Taylor & Francis in Teaching and Learning in Medicine
- Vol. 36 (2) , 211-221
Evolving from Didactic to Dialogic: How to Improve Faculty Development and Support Faculty Developers by Using Action Research
Problem: Since competency-based medical education has gained widespread acceptance to guide curricular reforms, faculty development has been regarded as an indispensable element to make these programs successful. Faculty developers have striven to design and deliver myriad of programs or workshops to better prepare faculty members for fulfilling their teaching roles. However, how faculty developers can improve workshop delivery by researching their teaching practices remains underexplored. Intervention: Action research aims to understand real world practices and advocates for formulation of doable plans through cycles of investigations, and ultimately contributes to claims of knowledge and a progression toward the goal of practice improvement. This methodology aligns with the aim of this study to understand how I could improve a faculty development workshop by researching my teaching practices. Context: In 2016, we conducted four cycles of action research in the context of mini-Clinical Evaluation Exercise (mini-CEX) workshops within a faculty development program aiming for developing teaching and assessment competence in faculty members. We collected multiple sources of qualitative data for thematic analysis, including my reflective journal, field notes taken by a researcher-observer, and post-workshop written reflection and feedback in portfolio from fourteen workshop attendees aiming to develop faculty teaching and assessment competence. Impact: By doing action research, I scrutinized each step as an opportunity for change, enacted adaptive practice and reflection on my teaching practices, and formulated action plans to transform a workshop design through each cycle. In so doing, my workshop evolved from didactic to dialogic with continuous improvement on enhanced engagement, focused discussion and participant empowerment through a collaborative inquiry into feedback practice. Moreover, these processes of action research also supported my growth as a faculty developer. Lessons Learned: The systematic approach of action research serves as a vehicle to enable faculty developers to investigate individual teaching practices as a self-reflective inquiry, to examine, rectify, and transform processes of program delivery, and ultimately introduce themselves as agents for change and improvement.
- 24 April 2023
- Published by Taylor & Francis in Teaching and Learning in Medicine
- Vol. 36 (2) , 211-221
Evolving from Didactic to Dialogic: How to Improve Faculty Development and Support Faculty Developers by Using Action Research
Problem: Since competency-based medical education has gained widespread acceptance to guide curricular reforms, faculty development has been regarded as an indispensable element to make these programs successful. Faculty developers have striven to design and deliver myriad of programs or workshops to better prepare faculty members for fulfilling their teaching roles. However, how faculty developers can improve workshop delivery by researching their teaching practices remains underexplored. Intervention: Action research aims to understand real world practices and advocates for formulation of doable plans through cycles of investigations, and ultimately contributes to claims of knowledge and a progression toward the goal of practice improvement. This methodology aligns with the aim of this study to understand how I could improve a faculty development workshop by researching my teaching practices. Context: In 2016, we conducted four cycles of action research in the context of mini-Clinical Evaluation Exercise (mini-CEX) workshops within a faculty development program aiming for developing teaching and assessment competence in faculty members. We collected multiple sources of qualitative data for thematic analysis, including my reflective journal, field notes taken by a researcher-observer, and post-workshop written reflection and feedback in portfolio from fourteen workshop attendees aiming to develop faculty teaching and assessment competence. Impact: By doing action research, I scrutinized each step as an opportunity for change, enacted adaptive practice and reflection on my teaching practices, and formulated action plans to transform a workshop design through each cycle. In so doing, my workshop evolved from didactic to dialogic with continuous improvement on enhanced engagement, focused discussion and participant empowerment through a collaborative inquiry into feedback practice. Moreover, these processes of action research also supported my growth as a faculty developer. Lessons Learned: The systematic approach of action research serves as a vehicle to enable faculty developers to investigate individual teaching practices as a self-reflective inquiry, to examine, rectify, and transform processes of program delivery, and ultimately introduce themselves as agents for change and improvement.
- Open Access
- 21 July 2021
- Published by Springer Nature in BMC Medical Education
- Vol. 21 (1) , 1-8
How does narrative medicine impact medical trainees’ learning of professionalism? A qualitative study
Background: Narrative medicine (NM) is an approach involving narrative skills and is regarded as a model for medical humanism and effective medical practice. This study aims to explore how NM impacts medical trainees’ learning of professionalism during a clerkship in a Taiwanese clinical setting. Methods: A qualitative interview study adopting a purposive sampling method was undertaken. Thirty medical trainees participated in this study, including five fifth-year medical students (MSs), ten sixth-year MSs, nine seventh-year MSs, and six postgraduate year (PGY) trainees. Thematic framework analysis was applied, and a modified realist evaluation approach was further used to analyse the interview data. Results: We identified self-exploration, reflection, and awareness of professional identity as mechanisms explaining how NM impacted professionalism learning in our participants. Furthermore, empathy, communication, doctor-patient relationship and understanding patients were identified as the outcomes of the NM intervention for trainees’ learning of professionalism. Conclusions: NM facilitates medical trainees’ self-exploration, reflection, and awareness of professional identity, thereby affecting their learning of professionalism in clinical settings. Adopting NM as an educational intervention in undergraduate medical education could play an important role in professionalism learning, as trainees can thereby be supported to gradually develop self-exploration and reflection capabilities and heightened awareness of professional identity reflectively through a narrative process.
- 21 July 2021
- Published by Springer Nature in BMC Medical Education
- Vol. 21 (1) , 1-8
Open AccessHow does narrative medicine impact medical trainees’ learning of professionalism? A qualitative study
Background: Narrative medicine (NM) is an approach involving narrative skills and is regarded as a model for medical humanism and effective medical practice. This study aims to explore how NM impacts medical trainees’ learning of professionalism during a clerkship in a Taiwanese clinical setting. Methods: A qualitative interview study adopting a purposive sampling method was undertaken. Thirty medical trainees participated in this study, including five fifth-year medical students (MSs), ten sixth-year MSs, nine seventh-year MSs, and six postgraduate year (PGY) trainees. Thematic framework analysis was applied, and a modified realist evaluation approach was further used to analyse the interview data. Results: We identified self-exploration, reflection, and awareness of professional identity as mechanisms explaining how NM impacted professionalism learning in our participants. Furthermore, empathy, communication, doctor-patient relationship and understanding patients were identified as the outcomes of the NM intervention for trainees’ learning of professionalism. Conclusions: NM facilitates medical trainees’ self-exploration, reflection, and awareness of professional identity, thereby affecting their learning of professionalism in clinical settings. Adopting NM as an educational intervention in undergraduate medical education could play an important role in professionalism learning, as trainees can thereby be supported to gradually develop self-exploration and reflection capabilities and heightened awareness of professional identity reflectively through a narrative process.
- Open Access
- 5 June 2021
- Published by Springer Nature in BMC Medical Education
- Vol. 21 (1) , 1-17
Understanding the lived experiences of medical learners in a narrative medicine course: a phenomenological study
Background: Reflection and various approaches to foster reflection have been regarded as an indispensable element in enhancing professional practice across different disciplines. With its inherent potential to engage learners in reflection and improvement, narrative medicine has been adopted in various settings. However, the relevance and effectiveness of reflection remains underexplored in the context of narrative medicine, specifically in regard to the concern about variability of learner acceptance and the way learners really make sense of these reflective activities. This study aimed to explore what medical learners experience through narrative medicine and the meanings they ascribe to the phenomenon of this narrative-based learning. Methods: Using a transcendental phenomenology approach, twenty medical learners were interviewed about their lived experiences of taking a narrative medicine course during their internal medicine clerkship rotation. Moustakas’ phenomenological analysis procedures were applied to review the interview data. Results: Six themes were identified: feeling hesitation, seeking guidance, shifting roles in narratives, questioning relationships, experiencing transformation, and requesting a safe learning environment. These themes shaped the essence of the phenomenon and illustrated what and how medical learners set out on a reflective journey in narrative medicine. These findings elucidate fundamental elements for educators to consider how narrative approaches can be effectively used to engage learners in reflective learning and practice. Conclusion: Adopting Moustakas’ transcendental phenomenology approach, a better understanding about the lived experiences of medical learners regarding learning in narrative medicine was identified. Learner hesitancy should be tackled with care by educators so as to support learners with strategies that address guidance, relationship, and learning environment. In so doing, medical learners can be facilitated to develop reflective capabilities for professional and personal growth.
- 5 June 2021
- Published by Springer Nature in BMC Medical Education
- Vol. 21 (1) , 1-17
Open AccessUnderstanding the lived experiences of medical learners in a narrative medicine course: a phenomenological study
Background: Reflection and various approaches to foster reflection have been regarded as an indispensable element in enhancing professional practice across different disciplines. With its inherent potential to engage learners in reflection and improvement, narrative medicine has been adopted in various settings. However, the relevance and effectiveness of reflection remains underexplored in the context of narrative medicine, specifically in regard to the concern about variability of learner acceptance and the way learners really make sense of these reflective activities. This study aimed to explore what medical learners experience through narrative medicine and the meanings they ascribe to the phenomenon of this narrative-based learning. Methods: Using a transcendental phenomenology approach, twenty medical learners were interviewed about their lived experiences of taking a narrative medicine course during their internal medicine clerkship rotation. Moustakas’ phenomenological analysis procedures were applied to review the interview data. Results: Six themes were identified: feeling hesitation, seeking guidance, shifting roles in narratives, questioning relationships, experiencing transformation, and requesting a safe learning environment. These themes shaped the essence of the phenomenon and illustrated what and how medical learners set out on a reflective journey in narrative medicine. These findings elucidate fundamental elements for educators to consider how narrative approaches can be effectively used to engage learners in reflective learning and practice. Conclusion: Adopting Moustakas’ transcendental phenomenology approach, a better understanding about the lived experiences of medical learners regarding learning in narrative medicine was identified. Learner hesitancy should be tackled with care by educators so as to support learners with strategies that address guidance, relationship, and learning environment. In so doing, medical learners can be facilitated to develop reflective capabilities for professional and personal growth.
- Open Access
- 5 February 2021
- Published by Springer Nature in Research Square
Evolving from Didactic to Dialogic: An Action Research for Improving Teaching Practices in the mini-CEX Workshops
BackgroundFaculty development is imperative to ensure successful outcomes in the training of competent physicians. However, how faculty developers can improve the delivery of an assessment workshop through researching their individual teaching practices remains unexplored.MethodsIn 2016, the authors conducted four cycles of action research in the context of mini-Clinical Evaluation Exercise (mini-CEX) workshops. Multiple sources of qualitative data, including a faculty developer’s reflective journal, field notes taken by a researcher-observer, and post-workshop written reflection and feedback from fourteen workshop attendees, were collected and analyzed thematically.ResultsBy doing action research, the faculty developer scrutinized each step as an opportunity for change, enacted adaptive practice and reflection on teaching practices and formulated action plans to transform a workshop design. In so doing, a workshop evolved from didactic to dialogic with continuous improvement on enhanced engagement, focused discussion and participant empowerment through a collaborative inquiry into feedback practice. These action research cycles also supported development of adaptive practice and identity formation in the faculty developer.ConclusionsThe systematic approach of action research serves as a vehicle to enable faculty developers to investigate individual teaching practices as a self-reflective inquiry, to examine, rectify, and transform processes of program delivery, and ultimately introduce themselves as agents for change and improvement.
- 5 February 2021
- Published by Springer Nature in Research Square
Open AccessEvolving from Didactic to Dialogic: An Action Research for Improving Teaching Practices in the mini-CEX Workshops
BackgroundFaculty development is imperative to ensure successful outcomes in the training of competent physicians. However, how faculty developers can improve the delivery of an assessment workshop through researching their individual teaching practices remains unexplored.MethodsIn 2016, the authors conducted four cycles of action research in the context of mini-Clinical Evaluation Exercise (mini-CEX) workshops. Multiple sources of qualitative data, including a faculty developer’s reflective journal, field notes taken by a researcher-observer, and post-workshop written reflection and feedback from fourteen workshop attendees, were collected and analyzed thematically.ResultsBy doing action research, the faculty developer scrutinized each step as an opportunity for change, enacted adaptive practice and reflection on teaching practices and formulated action plans to transform a workshop design. In so doing, a workshop evolved from didactic to dialogic with continuous improvement on enhanced engagement, focused discussion and participant empowerment through a collaborative inquiry into feedback practice. These action research cycles also supported development of adaptive practice and identity formation in the faculty developer.ConclusionsThe systematic approach of action research serves as a vehicle to enable faculty developers to investigate individual teaching practices as a self-reflective inquiry, to examine, rectify, and transform processes of program delivery, and ultimately introduce themselves as agents for change and improvement.
- Open Access
Alterations of Specific Lymphocytic Subsets with Aging and Age-Related Metabolic and Cardiovascular Diseases
To investigate the association of immunosenescence with aged-related morbidity in the elderly, a clinical study was conducted to analyze and compare the alterations in peripheral blood (PB) T-cell subsets among young healthy (YH) controls, elderly healthy (EH) controls, and age-matched elderly patients with metabolic diseases (E-MDs), with cardiovascular diseases (E-CVDs) or with both (E-MDs/E-CVDs). The frequencies of CD3T, CD8T and invariant natural killer T (iNKT) cells were decreased in the EH, E-MD and E-CVD cohorts, indicating a decline in defense function. Although CD4T and regulatory T (Treg) cell frequencies tended to increase with aging, they were lower in patients with E-MDs and E-CVDs. Subset analyses of T-cells consistently showed the accumulation of senescent T-cell in aging and in patients with E-MDs and E-CVDs, compared with YH volunteers. These accumulated senescent T-cells were undergoing apoptosis upon stimulation due to the replicative senescence stage of T-cells. In addition, serum levels of cytokines, including interferon (IF)-γ, transforming growth factor (TGF)-β and growth differentiation factor (GDF)-15, consistently reflected alterations in T-cell subsets. This study demonstrated that T-cell subset changes with paralleled alterations in cytokines were associated with aging and age-related pathogenesis. These altered T-cell subsets and/or cytokines can potentially serve as biomarkers for the prevention, diagnosis and treatment of age-related morbidities.
Open AccessAlterations of Specific Lymphocytic Subsets with Aging and Age-Related Metabolic and Cardiovascular Diseases
To investigate the association of immunosenescence with aged-related morbidity in the elderly, a clinical study was conducted to analyze and compare the alterations in peripheral blood (PB) T-cell subsets among young healthy (YH) controls, elderly healthy (EH) controls, and age-matched elderly patients with metabolic diseases (E-MDs), with cardiovascular diseases (E-CVDs) or with both (E-MDs/E-CVDs). The frequencies of CD3T, CD8T and invariant natural killer T (iNKT) cells were decreased in the EH, E-MD and E-CVD cohorts, indicating a decline in defense function. Although CD4T and regulatory T (Treg) cell frequencies tended to increase with aging, they were lower in patients with E-MDs and E-CVDs. Subset analyses of T-cells consistently showed the accumulation of senescent T-cell in aging and in patients with E-MDs and E-CVDs, compared with YH volunteers. These accumulated senescent T-cells were undergoing apoptosis upon stimulation due to the replicative senescence stage of T-cells. In addition, serum levels of cytokines, including interferon (IF)-γ, transforming growth factor (TGF)-β and growth differentiation factor (GDF)-15, consistently reflected alterations in T-cell subsets. This study demonstrated that T-cell subset changes with paralleled alterations in cytokines were associated with aging and age-related pathogenesis. These altered T-cell subsets and/or cytokines can potentially serve as biomarkers for the prevention, diagnosis and treatment of age-related morbidities.
- Open Access
- 10 May 2017
- Published by Springer Nature in BMC Medical Education
- Vol. 17 (1) , 1-8
Different perceptions of narrative medicine between Western and Chinese medicine students
Western medicine is an evidence-based science, whereas Chinese medicine is more of a healing art. To date, there has been no research that has examined whether students of Western and Chinese medicine differentially engage in, or benefit from, educational activities for narrative medicine. This study fills a gap in current literature with the aim of evaluating and comparing Western and Chinese Medicine students’ perceptions of narrative medicine as an approach to learning empathy and professionalism. An initial 10-item questionnaire with a 5-point Likert scale was developed to assess fifth-year Western medical (MS) and traditional Chinese medical (TCMS) students’ perceptions of a 4-activity narrative medicine program during a 13-week internal medicine clerkship. Exploratory factor analysis was undertaken. The response rate was 88.6% (412/465), including 270 (65.5%) MSs and 142 (34.5%) TCMSs, with a large reliability (Cronbach alpha = 0.934). Three factors were extracted from 9 items: personal attitude, self-development/reflection, and emotional benefit, more favorable in terms of enhancement of self-development/reflection. The perceptions of narrative medicine by scores between the two groups were significantly higher in TCMSs than MSs in all 9-item questionnaire and 3 extracted factors. Given the different learning cultures of medical education in which these student groups engage, this suggests that undertaking a course in Chinese medicine might enhance one’s acceptance to, and benefit from, a medical humanities course. Alternatively, Chinese medicine programmes might attract more humanities-focused students.
- 10 May 2017
- Published by Springer Nature in BMC Medical Education
- Vol. 17 (1) , 1-8
Open AccessDifferent perceptions of narrative medicine between Western and Chinese medicine students
Western medicine is an evidence-based science, whereas Chinese medicine is more of a healing art. To date, there has been no research that has examined whether students of Western and Chinese medicine differentially engage in, or benefit from, educational activities for narrative medicine. This study fills a gap in current literature with the aim of evaluating and comparing Western and Chinese Medicine students’ perceptions of narrative medicine as an approach to learning empathy and professionalism. An initial 10-item questionnaire with a 5-point Likert scale was developed to assess fifth-year Western medical (MS) and traditional Chinese medical (TCMS) students’ perceptions of a 4-activity narrative medicine program during a 13-week internal medicine clerkship. Exploratory factor analysis was undertaken. The response rate was 88.6% (412/465), including 270 (65.5%) MSs and 142 (34.5%) TCMSs, with a large reliability (Cronbach alpha = 0.934). Three factors were extracted from 9 items: personal attitude, self-development/reflection, and emotional benefit, more favorable in terms of enhancement of self-development/reflection. The perceptions of narrative medicine by scores between the two groups were significantly higher in TCMSs than MSs in all 9-item questionnaire and 3 extracted factors. Given the different learning cultures of medical education in which these student groups engage, this suggests that undertaking a course in Chinese medicine might enhance one’s acceptance to, and benefit from, a medical humanities course. Alternatively, Chinese medicine programmes might attract more humanities-focused students.