Leila Boukenna
Current Organizations / Institutes
The organizations/institutes from the scholar's latest article
Leila Boukenna has a total of 23 co-authors. Here are the top co-authors by number of shared publications:
- Artur Manuel Soares Silva
LAQV-REQUIMTE, Department of Chemistry, University of Aveiro, Campus de Santiago, 3810-193 Aveiro, Portugal
2 shared publications - Khaldoun Bachari
Centre de Recherche Scientifique et Technique en Analyses Physico-Chimiques
2 shared publications - Amina Taïbi
Laboratoire de Parasitologie et Mycologie, Laboratoire de Recherche « Santé et Production Animale, École Nationale Supérieure Vétérinaire, B.P. 228, Oued Smar- Alger, Algeria
1 shared publication - Brahim Cherfaoui
Centre de Recherche Scientifique et Technique en Analyses Physico-Chimiques (CRAPC) Zone Industrielle, BP 384, Tipaza, Algeria
1 shared publication - Farid Chebrouk
Centre de Recherche Scientifique et Technique en Analyses Physico‐Chimiques (CRAPC) Bou‐Ismail Tipaza Algeria
1 shared publication - Farida Khammar
Université des Sciences et de La Technologie Houari Boumediene (USTHB), Faculté des Sciences Biologiques (FSB), Laboratoire de Recherche sur Les Zones Arides, (LRZA), BP 32 El Alia 16111, Bab Ezzouar, 16111, Algeria
1 shared publication
Latest Publications
- 1 August 2021
- Published by Elsevier in Chemico-Biological Interactions
- Vol. 345, 109511
Molecular docking and dynamic studies of a potential therapeutic target inhibiting glyoxalase system: Metabolic action of the 3, 3 '- [3- (5-chloro-2-hydroxyphenyl) -3-oxopropane-1, 1-diyl] - Bis-4-hydroxycoumarin leads overexpression of the intracellular level of methylglyoxal and induction of a pro-apoptotic phenomenon in a hepatocellular carcinoma model
- 1 August 2021
- Published by Elsevier in Chemico-Biological Interactions
- Vol. 345, 109511
Molecular docking and dynamic studies of a potential therapeutic target inhibiting glyoxalase system: Metabolic action of the 3, 3 '- [3- (5-chloro-2-hydroxyphenyl) -3-oxopropane-1, 1-diyl] - Bis-4-hydroxycoumarin leads overexpression of the intracellular level of methylglyoxal and induction of a pro-apoptotic phenomenon in a hepatocellular carcinoma model
- Open Access
Hemi-Synthesis of Chiral Imine, Benzimidazole and Benzodiazepines from Essential Oil of Ammodaucus leucotrichus subsp. leucotrichus
The hemi-synthesis of chiral imine, benzimidazole and benzodiazepine structures is reported by the condensation of (S)-(−)-perillaldehyde, the major phytochemical of Ammodaucus leucotrichus subsp. leucotrichus essential oil, with different amine derivatives of 2,3-diaminomaleonitrile, o-phenylenediamine and 3-[(2-aminoaryl)amino]dimedone. The reaction proceeds in situ at ambient temperature without prior isolation of the natural (S)-(−)-perillaldehyde. Final products precipitate in the ethanolic reaction medium. 2D NMR and single-crystal X-ray diffraction studies were used to unequivocally characterize the structures in solution and in the solid state, respectively. Chiral HPLC analysis confirms the formation of unique enantiomers and diastereomeric mixtures.
Open AccessHemi-Synthesis of Chiral Imine, Benzimidazole and Benzodiazepines from Essential Oil of Ammodaucus leucotrichus subsp. leucotrichus
The hemi-synthesis of chiral imine, benzimidazole and benzodiazepine structures is reported by the condensation of (S)-(−)-perillaldehyde, the major phytochemical of Ammodaucus leucotrichus subsp. leucotrichus essential oil, with different amine derivatives of 2,3-diaminomaleonitrile, o-phenylenediamine and 3-[(2-aminoaryl)amino]dimedone. The reaction proceeds in situ at ambient temperature without prior isolation of the natural (S)-(−)-perillaldehyde. Final products precipitate in the ethanolic reaction medium. 2D NMR and single-crystal X-ray diffraction studies were used to unequivocally characterize the structures in solution and in the solid state, respectively. Chiral HPLC analysis confirms the formation of unique enantiomers and diastereomeric mixtures.