Santiago Mc Loughlin

The shortage of hospital beds and changes in the payment model have promoted an increased attention and financing of programs that focus on perioperative care efficiency in. Latin America. In this paper, Enhanced Recovery After Surgery (ERAS) programs developed by the ERAS® Society will be discussed. The implementation and use of ERAS®Society Guidelines consistently demonstrated a reduction in postoperative complications, hospital stay and costs. In the current paper, the definition of ERAS programs, their core elements, and the results of their implementation and regional developments are presented with special focus on Latin America.

Background: Acute compartment syndrome occurs when the tissue pressure within a closed muscle compartment exceeds the perfusion pressure. We observed diastolic retrograde arterial flow (DRAF) in 2 patients in the arteries proximal to compartment syndromes in injured limbs. We hypothesized that DRAF may represent an early sign of compartment pressure increments. Methods: We mimicked compartment syndrome by using a cuff to produce external compression of the forearm at increasing pressures. We correlated the applied pressure with brachial artery blood flow, velocities, and retrograde flow. We studied the brachial artery at baseline, at external compression of 40 mmHg applied to the forearm, at forearm compression equal to the patient's diastolic blood pressure (DBP), and at forearm compression equal to the patient's mean arterial pressure (MAP). Evaluations included Doppler velocities and DRAF percentage (%). Using a ROC analysis, we selected a DRAF (%) cutoff value for the identification of patients with an applied external pressure equal to or greater than their DBP and calculated its sensitivity and specificity. Results: Compared with baseline, DRAF (%) was increased at 40 mmHg (P< 0.05), at DBP (P< 0.05), and at MAP (P< 0.05). DRAF (%) was strongly correlated with applied external pressure (r=0.92, r(2)=0.85). DRAF 40% presented a 100% sensitivity and a 93% specificity for identifying a compression equal to or greater than the patient's DBP. Conclusion: DRAF (%) strongly correlates with the degree of external pressure applied to the brachial artery, suggesting it may represent a useful tool in the detection and evaluation of compartment syndrome.

Arm elevation induces diastolic retrograde flow in the brachial artery and an incremental rise in arterial compliance in healthy subjects with no modifications in vascular resistance. In contrast, changes in resistance have been observed after handgrip exercise. Our objective was to investigate if the resistance change induced by isometric handgrip exercise is able to reverse diastolic retrograde flow induced by arm elevation in a healthy population and to explore these adaptive changes in hypertensive subjects. Arterial flow velocity Doppler measurements were obtained including: (a) a baseline measurement, (b) measurement 30 s after arm elevation, (c) measurement during handgrip maneuver with the arm elevated, (d) measurement during handgrip release with the arm elevated. Our findings showed that diastolic retrograde flow is induced by arm elevation, partially increased by arm-up handgrip and completely reversed during arm-up handgrip release both in healthy and hypertensive subjects. As compared with normal subjects, deceleration time was longer in the hypertensive subjects during baseline but not during the arm-up stage, handgrip contraction and handgrip release stages. An important increase in deceleration time values from baseline to arm-up and handgrip contraction stages was observed in normal subjects but not in the hypertensive group. We believe that the highly significant difference in reactivity to postural changes observed in deceleration time values constitutes a promising hemodynamic index to investigate. Also, our observation of complete reversal of the retrograde flow during arm-up handgrip release provides a new approach to postural and exercise-induced vasomotor responses.