Masaru Okazaki
Current Organizations / Institutes
The organizations/institutes from the scholar's latest article
Research Subjects
Research Interests
Masaru Okazaki has a total of 9 co-authors. Here are the top co-authors by number of shared publications:
- Hidetoshi Yamashita
Department of Internal Medicine (Divisions of Cardiology, Hepatology, Geriatrics, and Integrated Medicine), Nippon Medical School, 1-1-5 Sendagi, 113-8603, Bunkyo-ku, Tokyo, Japan
1 shared publication - Kazuhito Ishii
Department of Microbiology and Immunology, Nippon Medical School, 1-1-5 Sendagi, Bunkyo-ku, Tokyo, 113-8602, Japan
1 shared publication - Kazunari Suzuki
Department of Internal Medicine (Divisions of Cardiology, Hepatology, Geriatric Medicine, and Integrated Medicine), Nippon Medical School, 1-1-5, Sendagi, Bunkyo-ku, Tokyo, 113-8603, Japan
1 shared publication - Kentaro Watanabe
Department of Internal Medicine (Divisions of Cardiology, Hepatology, Geriatrics and Integrated Medicine), Nippon Medical School, Tokyo, Japan
1 shared publication - Kenzo Oba
Division of Geriatric Medicine, Nippon Medical School, Japan
1 shared publication - Makoto Ohara
Showa Medical University Graduate School of Medicine, Japan
1 shared publication
Latest Publications
- Open Access
- 26 February 2013
- Published by Springer Nature in BMC Cardiovascular Disorders
- Vol. 13 (1) , 11
Relationship between postprandial glucose level and carotid artery stiffness in patients without diabetes or cardiovascular disease
The aim of this study was to evaluate the relationship between postprandial glucose level and atherosclerosis in patients without diabetes and cardiovascular disease by determining carotid ultrasonographic variables and serum levels of 1,5-anhydroglucitol (1,5-AG). The subjects were 72 patients without diabetes and cardiovascular disease being treated for hypertension or dyslipidemia. The clinical characteristics of all subjects, including the serum level of 1,5-AG, which appears to be well suited for monitoring postprandial hyperglycemia, were evaluated after an overnight fast. The average intima-media thickness (IMT) and the average pulsatility index (PI) of the right and left common carotid arteries were determined with high-resolution ultrasonography and used as ultrasonographic variables. The subjects were divided into a Lower 1,5-AG group (n = 36) and a Higher 1,5-AG group (n = 36). We evaluated the relationship between clinical characteristics and ultrasonographic variables of the carotid artery in both groups. The average PI in the Lower 1,5-AG group was significantly higher than that in the Higher 1,5-AG group, but the average IMT did not differ between the groups. Linear regression analysis, with the ultrasonographic variables as the dependent variables, with 1,5-AG as the independent variable, and adjusted for other clinical characteristics, showed significant correlation between 1,5-AG and the PI but not between 1,5-AG and IMT. Our results suggest that postprandial hyperglycemia increases carotid artery stiffness, but not morphological change, in patients without diabetes or cardiovascular disease.
- 26 February 2013
- Published by Springer Nature in BMC Cardiovascular Disorders
- Vol. 13 (1) , 11
Open AccessRelationship between postprandial glucose level and carotid artery stiffness in patients without diabetes or cardiovascular disease
The aim of this study was to evaluate the relationship between postprandial glucose level and atherosclerosis in patients without diabetes and cardiovascular disease by determining carotid ultrasonographic variables and serum levels of 1,5-anhydroglucitol (1,5-AG). The subjects were 72 patients without diabetes and cardiovascular disease being treated for hypertension or dyslipidemia. The clinical characteristics of all subjects, including the serum level of 1,5-AG, which appears to be well suited for monitoring postprandial hyperglycemia, were evaluated after an overnight fast. The average intima-media thickness (IMT) and the average pulsatility index (PI) of the right and left common carotid arteries were determined with high-resolution ultrasonography and used as ultrasonographic variables. The subjects were divided into a Lower 1,5-AG group (n = 36) and a Higher 1,5-AG group (n = 36). We evaluated the relationship between clinical characteristics and ultrasonographic variables of the carotid artery in both groups. The average PI in the Lower 1,5-AG group was significantly higher than that in the Higher 1,5-AG group, but the average IMT did not differ between the groups. Linear regression analysis, with the ultrasonographic variables as the dependent variables, with 1,5-AG as the independent variable, and adjusted for other clinical characteristics, showed significant correlation between 1,5-AG and the PI but not between 1,5-AG and IMT. Our results suggest that postprandial hyperglycemia increases carotid artery stiffness, but not morphological change, in patients without diabetes or cardiovascular disease.