Joachim Braun
Current Organizations / Institutes
The organizations/institutes from the scholar's latest article
Joachim Braun has a total of 6 co-authors. Here are the top co-authors by number of shared publications:
- Dorit Merhof
Interdisciplinary Center for Interactive Data Analysis, Modelling and Visual Exploration (INCIDE), University of Konstanz, 78457 Konstanz, Germany
1 shared publication - Enrico Bertini
Unit of Muscular and Neurodegenerative Diseases Bambino Gesù Children's Hospital, IRCCS Rome Italy
1 shared publication - Hendrik Strobelt
IBM Research, USA
1 shared publication - Oliver Deussen
University of Konstanz, Germany
1 shared publication - Thomas U. Mayer
Department of Biology, University of Konstanz, Konstanz, Germany
1 shared publication - Ulrich Groth
Department of Chemistry, University of Konstanz, Universitätsstr. 10, Konstanz 78457, Germany, http://www.ag-groth.chemie.uni-konstanz.de
1 shared publication
Latest Publications
- Open Access
- 18 May 2012
- Published by Springer Nature in BMC Bioinformatics
- Vol. 13 (S8) , S4
HiTSEE KNIME: a visualization tool for hit selection and analysis in high-throughput screening experiments for the KNIME platform
We present HiTSEE (High-Throughput Screening Exploration Environment), a visualization tool for the analysis of large chemical screens used to examine biochemical processes. The tool supports the investigation of structure-activity relationships (SAR analysis) and, through a flexible interaction mechanism, the navigation of large chemical spaces. Our approach is based on the projection of one or a few molecules of interest and the expansion around their neighborhood and allows for the exploration of large chemical libraries without the need to create an all encompassing overview of the whole library. We describe the requirements we collected during our collaboration with biologists and chemists, the design rationale behind the tool, and two case studies on different datasets. The described integration (HiTSEE KNIME) into the KNIME platform allows additional flexibility in adopting our approach to a wide range of different biochemical problems and enables other research groups to use HiTSEE.
- 18 May 2012
- Published by Springer Nature in BMC Bioinformatics
- Vol. 13 (S8) , S4
Open AccessHiTSEE KNIME: a visualization tool for hit selection and analysis in high-throughput screening experiments for the KNIME platform
We present HiTSEE (High-Throughput Screening Exploration Environment), a visualization tool for the analysis of large chemical screens used to examine biochemical processes. The tool supports the investigation of structure-activity relationships (SAR analysis) and, through a flexible interaction mechanism, the navigation of large chemical spaces. Our approach is based on the projection of one or a few molecules of interest and the expansion around their neighborhood and allows for the exploration of large chemical libraries without the need to create an all encompassing overview of the whole library. We describe the requirements we collected during our collaboration with biologists and chemists, the design rationale behind the tool, and two case studies on different datasets. The described integration (HiTSEE KNIME) into the KNIME platform allows additional flexibility in adopting our approach to a wide range of different biochemical problems and enables other research groups to use HiTSEE.