TFTetsuro Fujii

Tetsuro Fujii

*This is an algorithmically generated author record based on publicly available information.

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Tetsuro Fujii has a total of 18 co-authors. Here are the top co-authors by number of shared publications:


Latest Publications

  • Open Access

    Early effect of oral administration of omeprazole with mosapride as compared with those of omeprazole alone on the intragastric pH

    by Hiroshi Iida, Masahiko Inamori, Tetsuro Fujii, Yusuke Sekino, Hiroki Endo, Kunihiro Hosono, Takashi Nonaka, Tomoko Koide, Hirokazu Takahashi, Masato Yoneda, et al.

    Background: The ideal medication for acid-related diseases should have a rapid onset of action to promote hemostasis and cause efficient resolution of symptoms. The aim of our study was to comparatively investigate the inhibitory effect on gastric acid secretion of a single oral administration of omeprazole plus mosapride with that of omeprazole alone.Methods: Ten Helicobacter pylori-negative male subjects participated in this randomized, two-way crossover study. Intragastric pH was monitored continuously for 6 hours after a single oral administration of omeprazole 20 mg or that of omeprazole 20 mg plus mosapride 5 mg (the omeprazole being administered one hour after the mosapride). Each administration was separated by a 7-days washout period.Results: The average pH during the 6-hour period after administration of omeprazole 20 mg plus mosapride 5 mg was higher than that after administration of omeprazole 20 mg alone (median: 3.22 versus 4.21, respectively;p= 0.0247).Conclusions: In H. pylori -negative healthy male subjects, an oral dose of omeprazole 20 mg plus mosapride 5 mg increased the intragastric pH more rapidly than omeprazole 20 mg alone.