Despina Bazou
Current Organizations / Institutes
The organizations/institutes from the scholar's latest article
Research Subjects
Despina Bazou has a total of 3 co-authors. Here are the top co-authors by number of shared publications:
- Itziar González
Concejo Superior de Investigaciones Científicas (CSIC), Instituto de Tecnologías Físicas y de la Información (ITEFI), Madrid, Spain
1 shared publication - Lance L. Munn
Department of Radiation Oncology Massachusetts General Hospital and Harvard Medical School Boston Massachusetts USA
1 shared publication - Nir Maimon
Edwin L. Steele Laboratory, Department of Radiation Oncology, Massachusetts General Hospital, Harvard Medical School, 100 Blossom Street, Boston, MA 02114, USA
1 shared publication
Latest Publications
- Open Access
- 8 December 2017
- Published by MDPI AG in Applied Sciences
- Vol. 7 (12) , 1275
Effects of Low Intensity Continuous Ultrasound (LICU) on Mouse Pancreatic Tumor Explants
This paper describes the effects of low intensity continuous ultrasound (LICU) on the inflammatory response of mouse pancreatic tumor explants. While there are many reports focusing on the application of low-intensity pulsed ultrasound (LIPUS) on cell cultures and tissues, the effects of continuous oscillations on biological tissues have never been investigated. Here we present an exploratory study of the effects induced by LICU on mouse pancreatic tumor explants. We show that LICU causes significant upregulation of IFN-γ, IL-1β, and TNF-α on tumor explants. No detectable effects were observed on tumor vasculature or collagen I deposition, while thermal and mechanical effects were not apparent. Tumor explants responded as a single unit to acoustic waves, with spatial pressure variations smaller than their size.
- 8 December 2017
- Published by MDPI AG in Applied Sciences
- Vol. 7 (12) , 1275
Open AccessEffects of Low Intensity Continuous Ultrasound (LICU) on Mouse Pancreatic Tumor Explants
This paper describes the effects of low intensity continuous ultrasound (LICU) on the inflammatory response of mouse pancreatic tumor explants. While there are many reports focusing on the application of low-intensity pulsed ultrasound (LIPUS) on cell cultures and tissues, the effects of continuous oscillations on biological tissues have never been investigated. Here we present an exploratory study of the effects induced by LICU on mouse pancreatic tumor explants. We show that LICU causes significant upregulation of IFN-γ, IL-1β, and TNF-α on tumor explants. No detectable effects were observed on tumor vasculature or collagen I deposition, while thermal and mechanical effects were not apparent. Tumor explants responded as a single unit to acoustic waves, with spatial pressure variations smaller than their size.