Ramesh B. Dateer

An ecologically friendly, low-cost, and biogenic preparation of iron oxide nanoparticles (Fe₃O₄ NPs) via a green approach utilizing waste biomass material is reported. The catalyst efficiency for Friedel–Crafts acylation to access functionalized anisole under solvent-free conditions and synthesis of quinoxaline derivatives utilizing water as a green solvent is described. The Fe₃O₄ NPs were synthesized biogenically using an aqueous extract of areca nut husk (ANH) and subsequently confirmed by various standard spectroscopic and microscopic characterization techniques. FESEM analysis displayed a spherical, agglomerated porous morphology, while the XRD analysis displayed a crystal size of 2.31 nm. TG-DT analysis revealed the stability of the Fe₃O₄ NPs to be good up to 450 °C, and XPS analysis indicated Fe²⁺ and Fe³⁺ oxidation states of the catalyst. A series of anisole and quinoxaline derivatives were prepared in moderate to high yields using the catalyst, and catalyst recyclability, mechanistic elucidation, and gram-scale synthesis are described herein. Additionally, the gas sensing proficiency of Fe₃O₄ NPs was examined toward oxidizing as well as reducing gases, establishing their potential for value-added applications.

Overview of the MW-accelerated greener synthesis. Top: two-step sequential synthesis flow (step 1: SNAr at C-4 in GVL/DIPEA, MW, 80 °C; step 2: Suzuki–Miyaura at C-2 in EtOH–H ₂ O/PdCl ₂ (PPh ₃ ) ₂ , MW, 100 °C); Bottom: key greener chemistry metrics.

Nitrosobenzenes are versatile intermediates in organic synthesis. Their NO group on an aromatic ring gives them both electrophilic and nucleophilic character, enabling diverse reactivity in both metal-catalyzed and metal-free transformations.

We report a sustainable, magnetically separable Pd@FO-BCN nanocatalyst with minimal Pd loading for efficient ligand-free C-H functionalization in 2-phenylindole synthesis. This novel heterogeneous system shows broad functional group tolerance, high recyclability and excellent yields. Notably, 5-acetyl-2-phenylindole displayed promising anticancer activity, highlighting the nanocatalyst biomedical relevance and potential for pharmaceutical and materials chemistry applications.

A novel metal‐ and base‐free approach for the synthesis of benzoxazino and benzoxazepino fused isoquinoline derivatives from ortho‐alkynyl aldehydes and amines under mild reaction conditions has been described. The formation of new C−O and C−N bonds via metal‐free cyclization with internal alkyne aided by water molecules without using external ligands and bases has been described. In addition, a series of control experiments are performed, and mechanistic studies are discussed elaborately by Density Functional Theory (DFT) calculation. Furthermore, gram‐scale synthesis and photophysical studies of the synthesized compounds and their quantum yield calculation have been demonstrated.

Herein, we report an efficient methodology for the preparation of a heterogeneous sustainable magnetically separable Cu@PANI@Fe₃O₄ nanocomposite, and its catalytic efficiency in multicomponent reactions for the synthesis of triazolo quinolines and triazolyl benzamide derivatives is investigated.