Lin Tan

Bio-based SCT rapidly controls bleeding through morphology-driven transformation. SCCVF gauze confines blood, while porous GTG captures blood and adheres to tissue. SCT reduces blood loss and hemostasis time in animal models.

Microbial contamination in multidose ophthalmic drops primarily arises from bacteria surface adhesion and liquid backflow during use and storage. Traditional solutions relying on chemical preservatives or single-dose packaging face limitations concerning biocompatibility, environmental sustainability, and high cost. Therefore, the development of a bottle cap membrane that prevents backflow and bacterial contamination is crucial and highly meaningful. In this work, a series of cotton/polyurethane Janus composite membranes with unidirectional liquid transport, antibacterial, and bacteria-blocking functions were prepared by electrospinning and hot pressing technology. Remarkably, the structure of this composite membrane shows stable and excellent unidirectional liquid transport, with its one-way transport capacity (R) reaching grade 4 and its overall moisture management capacity (OMMC) reaching grade 5 (AATCC 195-2017). In addition, even after 50 times of washing, because polylysine (PL) is firmly fixed on cotton, the antibacterial rate of this composite membrane against S. aureus and E. coli still exceeds 99.9%. Moreover, depending on its micropore structure, its bacteria-blocking rate against S. aureus reached 99.4%, and its bacteria-blocking rate against E. coli also reached 76.9%. In addition to this, the composite membrane exhibits excellent biocompatibility, with a cell compatibility exceeding 75% and hemolysis below 5%. Collectively, this work provides a reliable solution to solve the problem of microbial pollution in the packaging of drug eye drops.

Regenerated cellulose/collagen fibers with improved mechanical properties, flame retardancy, UV protection, and antibacterial activity are developed through microstructural regulation and chemical crosslinking for multifunctional biomedical textiles.

This study developed a novel SCZrB/WPU fiberboard that integrates antibacterial, flame-retardant, and mosquito-repellent functionalities without compromising eco-compatibility.

This study designed a dual-layered PUF-PG-MA mesh for breast reconstruction by integrating shape-memory foam with antibacterial nanofibers, thereby significantly reducing infection, inflammation, and capsular contracture.

Wet spinning of nanocellulose in purely aqueous systems for functionalized filament formation represents a significant yet challenging research frontier. This study develops a sustainable wet-spinning approach to produce high-performance macrofibers using TEMPO-oxidized bacterial cellulose nanofibers (TOBCN), sodium alginate (Alg), and metal-phenolic networks (MPNs). The system utilizes Fe³⁺-mediated cross-linking in MPNs combined with Ca²⁺-induced ionic bonding with TOBCN to achieve enhanced mechanical properties. The optimized Alg/TAFe₁-TOBC₂ fiber demonstrates remarkable multifunctional characteristics, including photothermal antibacterial efficacy exceeding 99% against both Escherichia coli and Staphylococcus aureus, superior flame retardancy with 61.05% lower heat release compared to cotton, and excellent UV protection with UV protection factor values surpassing 100, which exceed standard textile requirements. The purely aqueous processing and biomass-based composition ensure environmental compatibility and biocompatibility. These macrofibers hold promise for protective textiles, combining sustainability with high performance.

Preparing high‐performance artificial spider silk with hierarchical structures using purely chemical synthesis methods is challenging, albeit promising. Herein, a high‐molecular‐weight pseudoprotein material (CPPUU) synthesized by introducing polypeptide fragments (PZLY) and cystine dimethyl ester (CDE) into a polyurethane/urea macromolecular chain is described. Nanofiber yarn is subsequently prepared using an improved electrospinning process. After pre‐stretching, the tensile strength of the nanofiber yarn is 286.0 ± 47.1 MPa, and the toughness is an unprecedented 925.4 ± 116.1 MJ m⁻³, surpassing that of both natural and synthetic fibers reported to date. Moreover, the nanofiber yarn can lift a weight 100 000 times its mass and withstand the free fall of a weight 25 000 times its mass. Structural analysis indicates that the yarn contains structures such as random coils, α‐helices, and β‐sheets commonly found in spider silk; additionally, the existence of β‐turns in pseudoprotein materials is verified. The hierarchical structural resemblance to spider silk and the stress–strain curve suggest that a self‐toughening mechanism is responsible for the excellent mechanical properties displayed by the yarn. This study should promote the production of artificial spider silk, with potential applications in various high‐performance materials and industries.