Jacqueline Stamm
Current Organizations / Institutes
The organizations/institutes from the scholar's latest article
Research Subjects
Jacqueline Stamm has a total of 12 co-authors. Here are the top co-authors by number of shared publications:
- Beatrix Suess
Department of Biology, Technical University of Darmstadt, Darmstadt, Germany
1 shared publication - Dieter Spiehl
Institute of Printing Science and Technology, Technical University of Darmstadt, Darmstadt, Germany
1 shared publication Dominik Daume
Institute of Printing Science and Technology, Technische Universität Darmstadt, Darmstadt, Germany
1 shared publicationEdgar Dörsam
Institute of Printing Science and Technology, Technische Universität Darmstadt, Darmstadt, Germany
1 shared publication- Edgar Dörsam
Technical University of Darmstadt
1 shared publication - Florian Groher
Department of Biology, Technische Universitat Darmstadt, 26536 Darmstadt, Hesse Germany
1 shared publication
Latest Publications
- 10 July 2019
- Published by Springer Nature in Journal of Coatings Technology and Research
- Vol. 16 (6) , 1663-1671
Dynamic interferometric imaging of the thickness distribution of evaporating thin liquid films
- 10 July 2019
- Published by Springer Nature in Journal of Coatings Technology and Research
- Vol. 16 (6) , 1663-1671
Dynamic interferometric imaging of the thickness distribution of evaporating thin liquid films
- Open Access
- 2 January 2019
- Published by MDPI AG in Biosensors
- Vol. 9 (1) , 7
Characterization and Inkjet Printing of an RNA Aptamer for Paper-Based Biosensing of Ciprofloxacin
The excessive use of antibiotics in food-producing animals causes a steady rise of multiple antibiotic resistance in foodborne bacteria. Next to sulfonamides, the most common antibiotics groups are fluoroquinolones, aminoglycosides, and ß-lactams. Therefore, there is a need for a quick, efficient, and low-cost detection procedure for antibiotics. In this study, we propose an inkjet-printed aptamer-based biosensor developed for the detection of the fluoroquinolone ciprofloxacin. Due to their extraordinary high affinity and specificity, aptamers are already widely used in various applications. Here we present a ciprofloxacin-binding RNA aptamer developed by systematic evolution of ligands by exponential enrichment (SELEX). We characterized the secondary structure of the aptamer and determined the KD to 36 nM that allow detection of antibiotic contamination in a relevant range. We demonstrate that RNA aptamers can be inkjet-printed, dried, and resolved while keeping their functionality consistently intact. With this proof of concept, we are paving the way for a potential range of additional aptamer-based, printable biosensors.
- 2 January 2019
- Published by MDPI AG in Biosensors
- Vol. 9 (1) , 7
Open AccessCharacterization and Inkjet Printing of an RNA Aptamer for Paper-Based Biosensing of Ciprofloxacin
The excessive use of antibiotics in food-producing animals causes a steady rise of multiple antibiotic resistance in foodborne bacteria. Next to sulfonamides, the most common antibiotics groups are fluoroquinolones, aminoglycosides, and ß-lactams. Therefore, there is a need for a quick, efficient, and low-cost detection procedure for antibiotics. In this study, we propose an inkjet-printed aptamer-based biosensor developed for the detection of the fluoroquinolone ciprofloxacin. Due to their extraordinary high affinity and specificity, aptamers are already widely used in various applications. Here we present a ciprofloxacin-binding RNA aptamer developed by systematic evolution of ligands by exponential enrichment (SELEX). We characterized the secondary structure of the aptamer and determined the KD to 36 nM that allow detection of antibiotic contamination in a relevant range. We demonstrate that RNA aptamers can be inkjet-printed, dried, and resolved while keeping their functionality consistently intact. With this proof of concept, we are paving the way for a potential range of additional aptamer-based, printable biosensors.