SMSabrina Manfredi

Sabrina Manfredi

*This is an algorithmically generated author record based on publicly available information.

Current Organizations / Institutes

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Sabrina Manfredi has a total of 42 co-authors. Here are the top co-authors by number of shared publications:


Latest Publications

  • High‐Field Magnetic Resonance Imaging Features of the Coelomic Organs in Three Species of Chelonians

    by Francesco Di Ianni, Alessandro Vetere, Sabrina Manfredi, Elena Tintoni, Igor Pelizzone, Martina Fumeo, Enrico Bigliardi, Laura Denti, Antonella Volta, Mattia Bonazzi

    The aim of this study was to describe the normal anatomy of coelomic organs in three different species of chelonians using high‐field magnetic resonance imaging (MRI). This study also describes a rapid study protocol to examine chelonians without the use of sedation. A 1.5‐T superconducting magnet with volume or surface coils was used for the study. Sixteen healthy turtles belonging to three different species: 3 yellow‐bellied sliders ( Trachemys scripta scripta ), 3 marginated tortoise ( Testudo marginata ), and 10 Hermann's tortoises ( Testudo hermanni ) were considered. The images were obtained using the following sequences: T1‐weighted (T1W) turbo spin echo (TSE) acquired in the transverse and dorsal planes, T2‐weighted (T2W) TSE 3D acquired in the sagittal plane, and short‐tau inversion recovery (STIR) in the transverse plane. No contrast medium was used. All studies were feasible, fast, and yielded images of good quality in all the sequences. TSE T2W images had the best signal‐to‐noise ratio. The scan time was approximately 15–20 min. The majority of the coelomic organs were clearly identified, with the exception of the pancreas, adrenal glands, and ureters. In conclusion, high‐field MRI in unsedated chelonians is feasible and fast and yields diagnostic images of the majority of the coelomic organs in all three species evaluated.


  • Diarrhea, vomiting, and anorexia in a 4-month-old male intact domestic shorthair cat

    by Eleonora Daga, Martina Fumeo, Sabrina Manfredi, Francesca Miduri, Fabio Leonardi, Mattia Bonazzi

    "Diarrhea, vomiting, and anorexia in a 4-month-old male intact domestic shorthair cat" published on 17 Mar 2023 by American Veterinary Medical Association.

  • Open Access

    Monitoring of the Reproductive Cycle in Captive-Bred Female Boa constrictor: Preliminary Ultrasound Observations

    by Mara Bertocchi, Enrico Bigliardi, Igor Pelizzone, Alessandro Vetere, Sabrina Manfredi, Diego Cattarossi, Matteo Rizzi, Francesco Di Ianni

    The Boa constrictor is one of the most common reptiles bred in captivity. To achieve a successful breeding season, thorough knowledge of the females’ reproductive activity is necessary. In this regard, information on the Boa constrictor is still rather scarce. The aim of the present study was to monitor the ovarian activity and the embryonic development of boas by ultrasound. We performed brief scans on thirty non-anaesthetized snakes using a portable ultrasound system and a 7.5–10 MHz linear array transducer (Esaote MyLab™ Classic). Ultrasound features, dimensions, and echogenicity of the preovulatory and postovulatory follicles were determined. As gestation progresses, the postovulatory follicle size increases, and the embryonic silhouette becomes increasingly recognizable. During the second month after ovulation, by using color Doppler, early embryos’ heart activity could be evaluated. It is possible to highlight vascular connections between the mother and the membrane covering the embryonic structures. Ultrasound also allows one to identify follicular regression or slugs (nonfertilized eggs) early. The present study suggests that ultrasound could be an excellent noninvasive technique to evaluate the reproductive activity of Boa constrictor, allowing us to precisely identify the correct time for mating, monitor embryo development and viability, and allow the early diagnosis of follicular regression.


  • Ultrasonographic differentiation between portal venous and parenchymal gas may be important for the prognosis of canine and feline hepatic emphysema: 37 cases

    by Sabrina Manfredi, Martina Fabbi, Mattia Bonazzi, Fabio Leonardi, Francesca Miduri, Ilaria Parroccini, Eleonora Daga, Giacomo Gnudi, Antonella Volta

    The aim of this retrospective, cross‐sectional, study was to evaluate clinical findings and outcomes for different ultrasonographic patterns of hepatic emphysema in dogs and cats. Dogs and cats with an ultrasonographic diagnosis of hepatic emphysema and a known outcome, from January 2010 to January 2018, were enrolled. The following data were recorded from medical and ultrasonographic records: ultrasonographic patterns of hepatic emphysema (parenchymal, portal venous, biliary), clinical signs, laboratory findings, and outcomes (favorable, poor). A total of 33 dogs and four cats met the inclusion criteria. Among these, 23 cases were classified as hepatic portal venous gas, 10 as parenchymal emphysema, and four as biliary emphysema. Clinical diagnosis categories were as follows: infection/sepsis (9), gastro‐intestinal disease (9), iatrogenic (9), trauma (5), and liver neoplasia (5). An increase in serum liver enzymes was significantly associated with parenchymal emphysema (P = .03). Other clinical and laboratory findings were not associated with the type of hepatic emphysema. Hepatic portal venous gas was mostly transient in patients with ultrasonographic follow‐up. The overall mortality was 40.5%. A significant difference was found between mortality by portal venous gas (21.7%) and mortality by parenchymal emphysema (90%) (P = .003). In conclusion, the ultrasonographic differentiation of hepatic emphysema between hepatic portal venous gas and parenchymal emphysema may be important for the prognosis of hepatic emphysema. The presence of parenchymal emphysema may be a poor prognostic indicator, while hepatic portal venous gas may be more benign. However, ultrasound findings should be carefully evaluated in the context of clinical findings.


  • Open Access

    Emphysematous cystitis: review of current literature, diagnosis and management challenges

    by Martina Fumeo, Sabrina Manfredi, Antonella Volta

    Emphysematous cystitis (EC) is a rare disease in human as well as in veterinary medicine; in both it is defined as an uncommon form of complicated urinary tract infection (UTI), characterized by the presence of gas within the bladder wall and lumen. While female dogs are at increased risk of developing an UTI, patients with EC are not subject to gender or age predisposition and may present with variable clinical manifestations. Diabetes mellitus (DM) appears as the most common risk factor for the development of EC, but many other underlying conditions have been mentioned in literature and should be taken into consideration. In case of EC, Escherichia coli appears to be the most common pathogen isolated from urine cultures. A conclusive diagnosis of EC requires necessarily the recourse to imaging methods, such as abdominal radiography and ultrasonography. An early diagnosis and appropriate medical therapy, consisting in protracted antibiotic treatment associated with control over underlying diseases, could lead to avoid surgical intervention.


  • Complications of ultrasound-guided cystocentesis in companion animals: 21 cases (2005–2016)

    by Sabrina Manfredi, Cibele Carvahlo, Paolo Fonti, Giacomo Gnudi, Francesca Miduri, Martina Fabbi, Eleonora Daga, Manuela Ravera, Simona Morabito, Edoardo Auriemma, et al.


    • 1 April 2018
      • Vol. 82  (2) , 154-158

    Effect of a commercially available fish-based dog food enriched with nutraceuticals on hip and elbow dysplasia in growing Labrador retrievers

    by Sabrina Manfredi, Francesco Di Ianni, Nicola Di Girolamo, Sergio Canello, Giacomo Gnudi, Gianandrea Guidetti, Francesca Miduri, Martina Fabbi, Eleonora Daga, Enrico Parmigiani, et al.

    The aim of this study was to evaluate the prevalence of hip and elbow dysplasia in a group of growing Labrador retrievers fed a fish-based diet enriched with nutraceuticals with chondroprotective properties. The puppies ranged from 3 to 12 mo of age and were divided into 2 groups, each fed a different diet. The control diet consisted of a high quality, chicken-based dog food, while the test diet was a fish-based dog food, enriched with nutraceuticals. Hip and elbow joints were radiographed and scored at 6 and 12 mo of age. Overall, 42 dogs completed the study. At 12 mo of age, no differences were found between the groups in the prevalence of hip and elbow dysplasia, although dogs fed the fish-based food enriched with nutraceuticals had a less severe grade of osteoarthritis at 12 mo. It was concluded that the fish-based diet with nutraceuticals did have beneficial effects on the development of severe osteoarthritis.


  • USE OF ULTRASONOGRAPHY AND CONTRAST RADIOGRAPHY FOR SNAKE GENDER DETERMINATION

    by Giacomo Gnudi, Antonella Volta, Francesco DI Ianni, Mattia Bonazzi, Sabrina Manfredi, Giorgio Bertoni

    The purpose of this paper is to characterize the sonographic and radiographic features of hemipenes in male snakes and to use these features for gender determination. The sonographic and radiographic examination of 17 male and 10 female snakes, whose gender was determined previously by probing, were evaluated by one examiner who was unaware of the gender. Sonographically, hemipenes appeared funnel shaped with an echogenic thin wall and hypo to anechoic contents. Radiographically, hemipenes filled by positive contrast medium appeared as funnel‐shaped radiopacities pointing caudally. Snake gender was correctly determined in all snakes using sonography (accuracy=100%). Radiographic accuracy was 81.4%. Interpretation of radiographic examinations was limited by poor distribution of the contrast medium within the hemipenes.