Saulius Vosylius
Current Organizations / Institutes
The organizations/institutes from the scholar's latest article
Saulius Vosylius has a total of 13 co-authors. Here are the top co-authors by number of shared publications:
- Aidanas Preikšaitis
Centre of Neurosurgery, Clinic of Neurology and Neurosurgery, Faculty of Medicine, Vilnius University, 03101 Vilnius, Lithuania
1 shared publication - Akvile Sabestinaite
Center of Anaesthesiology Reanimatology and Critical Care Medicine, Republican Vilnius University Hospital, Vilnius, Lithuania.
1 shared publication - Arminas Ragauskas
Health Telematics Science Institute, Kaunas University of Technology, LT-51423 Kaunas, Lithuania
1 shared publication - Edvinas Chaleckas
Health Telematics Science Institute, Kaunas University of Technology, LT-51423 Kaunas, Lithuania
1 shared publication - Indre Lapinskiene
Clinic of Anaesthesiology and Intensive Care, Institute of Clinical Medicine, Faculty of Medicine, Vilnius University, LT-03101 Vilnius, Lithuania
1 shared publication - Laimonas Bartusis
Health Telematics Science Institute, Kaunas University of Technology, LT-51423 Kaunas, Lithuania
1 shared publication
Latest Publications
- Open Access
First-in-Human Prospective, Observational, and Comparative Clinical Study of Simultaneous Invasive and Non-Invasive Intracranial Pressure Pulse Wave Monitoring
Monitoring intracranial pressure (ICP) dynamics is critical for the management of traumatic brain injury, stroke, other neurosurgical conditions, and cerebral blood flow autoregulation; however, invasive ICP monitoring carries risks such as infection, hemorrhage, and sensor zero drift. Increasing evidence suggests that ICP waveform morphology provides clinically relevant information beyond mean ICP value alone. In this first-in-human prospective comparative clinical study, we evaluated the feasibility and accuracy of a novel, fully passive, non-invasive ICP pulse waveform monitoring system (Archimedes 02) based on the detection of eyeball mechanical movement. Fifteen intensive care unit patients (6 males, 9 females; mean age 57.1 ± 18.8 years) with clinically indicated invasive ICP monitoring or external ventricular drainage were enrolled. Three-minute monitoring sessions were performed to simultaneously acquire non-invasive ICP pulse waveforms, invasive ICP waveforms, and invasive radial artery blood pressure (ABP) waveforms. Averaged waveforms were derived for each patient and compared graphically and using correlation analysis. Non-invasive ICP pulse waves recorded with Archimedes 02 showed a strong correlation with invasive ICP waveforms ( = 0.965). In contrast, correlations between non-invasive ICP and ABP waveforms ( = 0.699), as well as between invasive ICP and ABP waveforms ( = 0.749), were lower. These findings indicate that the non-invasive signal primarily reflects ICP dynamics rather than arterial blood pressure. This novel non-invasive ICP monitoring approach has the potential to enhance neurocritical care, particularly in settings where invasive monitoring is impractical or unavailable. Further validation in larger and more diverse patient populations is warranted.Open AccessFirst-in-Human Prospective, Observational, and Comparative Clinical Study of Simultaneous Invasive and Non-Invasive Intracranial Pressure Pulse Wave Monitoring
Monitoring intracranial pressure (ICP) dynamics is critical for the management of traumatic brain injury, stroke, other neurosurgical conditions, and cerebral blood flow autoregulation; however, invasive ICP monitoring carries risks such as infection, hemorrhage, and sensor zero drift. Increasing evidence suggests that ICP waveform morphology provides clinically relevant information beyond mean ICP value alone. In this first-in-human prospective comparative clinical study, we evaluated the feasibility and accuracy of a novel, fully passive, non-invasive ICP pulse waveform monitoring system (Archimedes 02) based on the detection of eyeball mechanical movement. Fifteen intensive care unit patients (6 males, 9 females; mean age 57.1 ± 18.8 years) with clinically indicated invasive ICP monitoring or external ventricular drainage were enrolled. Three-minute monitoring sessions were performed to simultaneously acquire non-invasive ICP pulse waveforms, invasive ICP waveforms, and invasive radial artery blood pressure (ABP) waveforms. Averaged waveforms were derived for each patient and compared graphically and using correlation analysis. Non-invasive ICP pulse waves recorded with Archimedes 02 showed a strong correlation with invasive ICP waveforms ( = 0.965). In contrast, correlations between non-invasive ICP and ABP waveforms ( = 0.699), as well as between invasive ICP and ABP waveforms ( = 0.749), were lower. These findings indicate that the non-invasive signal primarily reflects ICP dynamics rather than arterial blood pressure. This novel non-invasive ICP monitoring approach has the potential to enhance neurocritical care, particularly in settings where invasive monitoring is impractical or unavailable. Further validation in larger and more diverse patient populations is warranted. - 24 November 2019
- Published by SRUMB - Romanian Society for Ultrasonography in Medicine and Biology in Medical Ultrasonography
- Vol. 21 (4) , 435-440
Optimal head rotation angle for safe right internal jugular vein catheterization using out-of-plane approach: an ultrasonography study
Aim: The most common complication following internal jugular vein catheterization is the puncture of the common carotidartery. We aimed to find an optimal head rotation angle for safe vein catheter insertion while minimizing the risk of arterypuncture.Materials and methods: Eighty-two patients admitted to the intensive care unit were included in the prospective study. Ultrasound examination of the neck vessels on the right side was performed in the neutral position and at a head rotation of 15°, 30°, 45° and 60° to the left. Internal jugular vein and common carotid artery puncture angle, overlapping angle of vein by artery and vein safe puncture angle were evaluated.Results: The internal jugular vein puncture angle increased with head rotation from the neutral position to 30° and 45° and was largest at 60° (p<0.001 for all). The overlapping angle increased significantly at 45° and 60° rotation compared with the neutral position (p<0.001 for all). The vein safe puncture angle was highest at 30° and significantly different from the neutral position and 60° (p=0.003 and p=0.013, respectively).Conclusions: When performing right internal jugular vein catheterization without ultrasound guidance by using an out-of-plane technique, the head should be rotated at 30°, because the overlapping angle increases with further head rotation and can increase the risk of artery puncture.
- 24 November 2019
- Published by SRUMB - Romanian Society for Ultrasonography in Medicine and Biology in Medical Ultrasonography
- Vol. 21 (4) , 435-440
Optimal head rotation angle for safe right internal jugular vein catheterization using out-of-plane approach: an ultrasonography study
Aim: The most common complication following internal jugular vein catheterization is the puncture of the common carotidartery. We aimed to find an optimal head rotation angle for safe vein catheter insertion while minimizing the risk of arterypuncture.Materials and methods: Eighty-two patients admitted to the intensive care unit were included in the prospective study. Ultrasound examination of the neck vessels on the right side was performed in the neutral position and at a head rotation of 15°, 30°, 45° and 60° to the left. Internal jugular vein and common carotid artery puncture angle, overlapping angle of vein by artery and vein safe puncture angle were evaluated.Results: The internal jugular vein puncture angle increased with head rotation from the neutral position to 30° and 45° and was largest at 60° (p<0.001 for all). The overlapping angle increased significantly at 45° and 60° rotation compared with the neutral position (p<0.001 for all). The vein safe puncture angle was highest at 30° and significantly different from the neutral position and 60° (p=0.003 and p=0.013, respectively).Conclusions: When performing right internal jugular vein catheterization without ultrasound guidance by using an out-of-plane technique, the head should be rotated at 30°, because the overlapping angle increases with further head rotation and can increase the risk of artery puncture.
- Open Access
- 1 January 2010
- Published by Vilnius University Press in Lietuvos chirurgija
- Vol. 8 (1)
Organų donoro priežiūra intensyviosios terapijos skyriuje
Viktorija Černiauskienė, Monika Čiplytė, Saulius VosyliusVilniaus universiteto Anesteziologijos ir reanimatologijos klinika, Vilniaus greitosios pagalbos universitetinė ligoninė,Šiltnamių g. 29, LT-04130 VilniusEl paštas: saulius.vosylius@gmail.com Įvadas / tikslasDonorinių organų poreikis gerokai viršija atliktų organų transplantacijų skaičių. Dažniausios priežastys, dėl kurių potencialūs donorai netampa efektyviais donorais, yra donoro artimųjų prieštaravimas donorystei, medicininės kontraindikacijos, logistikos problemos, neadekvatus potencialių donorų gydymas iki eksplantacijos operacijos. Šio straipsnio tikslas yra apžvelgti naujausius medicinos mokslo laimėjimus atliekant potencialių organų donorų priežiūrą reanimacijos ir intensyviosios terapijos skyriuose. Metodai ir rezultataiIšliekant žymiam atotrūkiui tarp organų pasiūlos ir poreikio, būtina kuo efektyviau panaudoti esamus resursus, daugiau dėmesio skiriant tinkamai potencialaus organų donoro intensyviajai terapijai. Dėl smegenų mirties įvyksta sunkūs daugelio organizmui svarbių funkcijų sutrikimai: kraujotakos ir kvėpavimo sistemų, endokrininiai, elektrolitų balanso sutrikimai, hipotermija, koagulopatija ir intensyvus sisteminis uždegimo atsakas. IšvadosPasirinkta tinkama intensyviosios terapijos taktika galėtų padidinti transplantacijai tinkamų organų skaičių, išlaikyti geresnę jų funkciją po transplantacijos. Reikšminiai žodžiai: smegenų mirtis, intensyviosios terapijos skyriai, audinių ir organų donorystė, gairės Organ donor management in the intensive care unit Viktorija Černiauskienė, Monika Čiplytė, Saulius VosyliusClinic of Anaesthesiology and Intensive Care, Vilnius University,Šiltnamių Str. 29, LT-04130 Vilnius, LithuaniaE-mail: saulius.vosylius@gmail.com Background / objectiveThe demand for donor organs greatly exceeds the number of transplantations. Many reasons may determine this inadequacy, such as family refusal, medical contraindications, logistics problems and inadequate management of the organ donor. The aim of the study was to present the recent achievements of medical practice in the management of organ donors in intensive care units. Methods and resultsWhile the discrepancy between the number of organ donations and transplantations persists, it is essential to use available resources more effectively, paying more attention to the intensive care management of the organ donor. Many physiological changes follow after brain death, such as cardiovascular and pulmonary dysfunction, endocrine and homeostasis disturbances, hypothermia, coagulopathy and an enhanced inflammatory response. ConclusionsOptimal intensive care could increase the number of organs available for transplantation and improve their function after it. Keywords: brain death, intensive care units, tissue and organ procurement, guidelines as topic
- 1 January 2010
- Published by Vilnius University Press in Lietuvos chirurgija
- Vol. 8 (1)
Open AccessOrganų donoro priežiūra intensyviosios terapijos skyriuje
Viktorija Černiauskienė, Monika Čiplytė, Saulius VosyliusVilniaus universiteto Anesteziologijos ir reanimatologijos klinika, Vilniaus greitosios pagalbos universitetinė ligoninė,Šiltnamių g. 29, LT-04130 VilniusEl paštas: saulius.vosylius@gmail.com Įvadas / tikslasDonorinių organų poreikis gerokai viršija atliktų organų transplantacijų skaičių. Dažniausios priežastys, dėl kurių potencialūs donorai netampa efektyviais donorais, yra donoro artimųjų prieštaravimas donorystei, medicininės kontraindikacijos, logistikos problemos, neadekvatus potencialių donorų gydymas iki eksplantacijos operacijos. Šio straipsnio tikslas yra apžvelgti naujausius medicinos mokslo laimėjimus atliekant potencialių organų donorų priežiūrą reanimacijos ir intensyviosios terapijos skyriuose. Metodai ir rezultataiIšliekant žymiam atotrūkiui tarp organų pasiūlos ir poreikio, būtina kuo efektyviau panaudoti esamus resursus, daugiau dėmesio skiriant tinkamai potencialaus organų donoro intensyviajai terapijai. Dėl smegenų mirties įvyksta sunkūs daugelio organizmui svarbių funkcijų sutrikimai: kraujotakos ir kvėpavimo sistemų, endokrininiai, elektrolitų balanso sutrikimai, hipotermija, koagulopatija ir intensyvus sisteminis uždegimo atsakas. IšvadosPasirinkta tinkama intensyviosios terapijos taktika galėtų padidinti transplantacijai tinkamų organų skaičių, išlaikyti geresnę jų funkciją po transplantacijos. Reikšminiai žodžiai: smegenų mirtis, intensyviosios terapijos skyriai, audinių ir organų donorystė, gairės Organ donor management in the intensive care unit Viktorija Černiauskienė, Monika Čiplytė, Saulius VosyliusClinic of Anaesthesiology and Intensive Care, Vilnius University,Šiltnamių Str. 29, LT-04130 Vilnius, LithuaniaE-mail: saulius.vosylius@gmail.com Background / objectiveThe demand for donor organs greatly exceeds the number of transplantations. Many reasons may determine this inadequacy, such as family refusal, medical contraindications, logistics problems and inadequate management of the organ donor. The aim of the study was to present the recent achievements of medical practice in the management of organ donors in intensive care units. Methods and resultsWhile the discrepancy between the number of organ donations and transplantations persists, it is essential to use available resources more effectively, paying more attention to the intensive care management of the organ donor. Many physiological changes follow after brain death, such as cardiovascular and pulmonary dysfunction, endocrine and homeostasis disturbances, hypothermia, coagulopathy and an enhanced inflammatory response. ConclusionsOptimal intensive care could increase the number of organs available for transplantation and improve their function after it. Keywords: brain death, intensive care units, tissue and organ procurement, guidelines as topic
- Open Access
- 1 January 2008
- Published by Vilnius University Press in Lietuvos chirurgija
- Vol. 6 (4)
Sepsio diagnostika
Saulius VosyliusAnesteziologijos ir reanimatologijos klinika, Vilniaus universitetas,Šiltnamių g. 29, LT-04130 VilniusEl paštas: saulius.vosylius@gmail.com Įvadas / tikslas Sepsio diagnostika visada buvo diskusijų objektas. Anksti patvirtinta diagnozė ir pradėtas gydymas yra labai svarbūs sepsiu sergantiems kritinių būklių pacientams. Metodai Sepsio diagnostikos kriterijai ir su juo susijusios būklės yra nepakankamai aiškiai apibūdinamos. Tarptautinė intensyviosios terapijos draugijų sutarimo konferencija 1991 metais pasiūlė, o vėliau 2001 metais papildė sepsio ir su juo susijusių būklių diagnostikos rodiklius. Rezultatai Infekcija pasireiškia patologiniu procesu patogeniniams mikroorganizmams patekus į normaliai sterilius audinius, ertmes ar skysčius. Sepsis diagnozuojamas nustačius sisteminio uždegimo atsako simptomus, susijusius su kliniškai aiškia infekcija. Sepsiui būdingi klinikiniai simptomai yra nespecifiniai infekcijai. Diagnozei patvirtinti ir paciento būklės kitimui įvertinti būtina naudoti kriterijų derinius. Sepsio diagnozė, pagrįsta klinikiniais kriterijais, patvirtinama laboratoriniais ir mikrobiologiniais tyrimais. Sunkus sepsis – sepsis, komplikavęsis audinių hipoperfuzija ar organų funkcijos sutrikimu. Sepsinis šokas yra sepsio sukeltas ūmus kraujotakos nepakankamumas, pasireiškiantis su kitomis priežastimis nesusijusia arterine hipotenzija, išliekančia infuzine terapija koregavus hipovolemiją. Išvados Ankstyva sepsio diagnostika leidžia užtikrinti tinkamą gydymą ir pasiekti geresnius gydymo rezultatus. Sepsio klinikinės diagnozės, būklės sunkumo, gydymo efektyvumo įvertinimo kriterijų paieška tebevyksta. Jie turėtų būti specifiški infekcijai, vertinti sisteminio uždegimo atsaką, jo intensyvumą. Reikšminiai žodžiai: sepsis, diagnozė, infekcija, sisteminio uždegimo atsako sindromas, dauginis organų nepakankamumas, uždegimo mediatoriai Diagnosis of sepsis Saulius VosyliusClinic of Anaesthesiology and Intensive Care, Vilnius University,Šiltnamių str. 29, LT-04130 Vilnius, LithuaniaE-mail: saulius.vosylius@gmail.com Background / objective The diagnosis of sepsis has always been an object for discussion. Early diagnosis and therapy are important in the management of critically ill patients. Methods Diagnostic criteria for sepsis and related states are still not well defined. The International Intensive Care Society conference held in 1991 proposed and later in 2001 revised the definitions of sepsis and related conditions. Results Infection is a pathologic process caused by the invasion of normally sterile tissue or fluid or body cavity by pathogenic microorganisms. Sepsis is defined as systemic inflammation caused by infection. Clinical signs related to sepsis are not specific to infection. To diagnose and monitor sepsis and to guide therapy, currently it is necessary to employ a combination of parameters. The diagnosis of sepsis is supported by clinical criteria and confirmed by laboratory parameters and microbiological data. Severe sepsis are confirmed when sepsis is complicated by tissue hypoperfusion and organ dysfunction. Septic shock refers to a state of acute circulatory failure characterized by persistent arterial hypotension unexplained by other causes. Conclusions Early diagnosis of sepsis is crucial in providing adequate therapy and improving the outcome. The search for the parameters of the diagnosis and monitoring the progress of sepsis is continuing. It should be specific for the diagnosis of infection, reflect the systemic inflammation, and correlate well with inflammation intensity. Key words: sepsis, diagnosis, infection, systemic inflammatory response syndrome, multiple organ failure, inflammation mediators
- 1 January 2008
- Published by Vilnius University Press in Lietuvos chirurgija
- Vol. 6 (4)
Open AccessSepsio diagnostika
Saulius VosyliusAnesteziologijos ir reanimatologijos klinika, Vilniaus universitetas,Šiltnamių g. 29, LT-04130 VilniusEl paštas: saulius.vosylius@gmail.com Įvadas / tikslas Sepsio diagnostika visada buvo diskusijų objektas. Anksti patvirtinta diagnozė ir pradėtas gydymas yra labai svarbūs sepsiu sergantiems kritinių būklių pacientams. Metodai Sepsio diagnostikos kriterijai ir su juo susijusios būklės yra nepakankamai aiškiai apibūdinamos. Tarptautinė intensyviosios terapijos draugijų sutarimo konferencija 1991 metais pasiūlė, o vėliau 2001 metais papildė sepsio ir su juo susijusių būklių diagnostikos rodiklius. Rezultatai Infekcija pasireiškia patologiniu procesu patogeniniams mikroorganizmams patekus į normaliai sterilius audinius, ertmes ar skysčius. Sepsis diagnozuojamas nustačius sisteminio uždegimo atsako simptomus, susijusius su kliniškai aiškia infekcija. Sepsiui būdingi klinikiniai simptomai yra nespecifiniai infekcijai. Diagnozei patvirtinti ir paciento būklės kitimui įvertinti būtina naudoti kriterijų derinius. Sepsio diagnozė, pagrįsta klinikiniais kriterijais, patvirtinama laboratoriniais ir mikrobiologiniais tyrimais. Sunkus sepsis – sepsis, komplikavęsis audinių hipoperfuzija ar organų funkcijos sutrikimu. Sepsinis šokas yra sepsio sukeltas ūmus kraujotakos nepakankamumas, pasireiškiantis su kitomis priežastimis nesusijusia arterine hipotenzija, išliekančia infuzine terapija koregavus hipovolemiją. Išvados Ankstyva sepsio diagnostika leidžia užtikrinti tinkamą gydymą ir pasiekti geresnius gydymo rezultatus. Sepsio klinikinės diagnozės, būklės sunkumo, gydymo efektyvumo įvertinimo kriterijų paieška tebevyksta. Jie turėtų būti specifiški infekcijai, vertinti sisteminio uždegimo atsaką, jo intensyvumą. Reikšminiai žodžiai: sepsis, diagnozė, infekcija, sisteminio uždegimo atsako sindromas, dauginis organų nepakankamumas, uždegimo mediatoriai Diagnosis of sepsis Saulius VosyliusClinic of Anaesthesiology and Intensive Care, Vilnius University,Šiltnamių str. 29, LT-04130 Vilnius, LithuaniaE-mail: saulius.vosylius@gmail.com Background / objective The diagnosis of sepsis has always been an object for discussion. Early diagnosis and therapy are important in the management of critically ill patients. Methods Diagnostic criteria for sepsis and related states are still not well defined. The International Intensive Care Society conference held in 1991 proposed and later in 2001 revised the definitions of sepsis and related conditions. Results Infection is a pathologic process caused by the invasion of normally sterile tissue or fluid or body cavity by pathogenic microorganisms. Sepsis is defined as systemic inflammation caused by infection. Clinical signs related to sepsis are not specific to infection. To diagnose and monitor sepsis and to guide therapy, currently it is necessary to employ a combination of parameters. The diagnosis of sepsis is supported by clinical criteria and confirmed by laboratory parameters and microbiological data. Severe sepsis are confirmed when sepsis is complicated by tissue hypoperfusion and organ dysfunction. Septic shock refers to a state of acute circulatory failure characterized by persistent arterial hypotension unexplained by other causes. Conclusions Early diagnosis of sepsis is crucial in providing adequate therapy and improving the outcome. The search for the parameters of the diagnosis and monitoring the progress of sepsis is continuing. It should be specific for the diagnosis of infection, reflect the systemic inflammation, and correlate well with inflammation intensity. Key words: sepsis, diagnosis, infection, systemic inflammatory response syndrome, multiple organ failure, inflammation mediators