Ahmed A. El-Abssawy
Current Organizations / Institutes
The organizations/institutes from the scholar's latest article
Research Subjects
Research Interests
Ahmed A. El-Abssawy has a total of 10 co-authors. Here are the top co-authors by number of shared publications:
- Anita Colombo
POLARIS Research Center, Department of Earth and Environmental Sciences, University of Milano-Bicocca, Milan, Italy
1 shared publication - Asmaa El-Mekawy
Air Pollution Department, Environment and Climate Change Research Institute, National Research Centre, Cairo, Egypt
1 shared publication - Atef Mohamed Fathy Mohammed
Air Pollution Research Department, Environment and Climate Change Research Institute, National Research Centre, Cairo 12622, Egypt
1 shared publication - Elham Farouk Mohamed
Air Pollution Department, Environment and Climate Change Research Institute, National Research Centre, Dokki, Egypt
1 shared publication - Maurizio Gualtieri
POLARIS Research Center, Department of Earth and Environmental Sciences, University of Milano-Bicocca, Piazza della Scienza 1, 20126 Milan, Italy
1 shared publication - Paride Mantecca
POLARIS Research Centre, Dept. of Earth and Environmental Sciences, University of Milano-Bicocca, Milano, 20126, Italy
1 shared publication
Latest Publications
- Open Access
- 9 October 2019
- Published by MDPI AG in International Journal of Molecular Sciences
- Vol. 20 (20) , 4970
Seasonal Variation in the Biological Effects of PM2.5 from Greater Cairo
Greater Cairo (Egypt) is a megalopolis where the studies of the air pollution events are of extremely high relevance, for the geographical-climatological aspects, the anthropogenic emissions and the health impact. While preliminary studies on the particulate matter (PM) chemical composition in Greater Cairo have been performed, no data are yet available on the PM’s toxicity. In this work, the in vitro toxicity of the fine PM (PM2.5) sampled in an urban area of Greater Cairo during 2017–2018 was studied. The PM2.5 samples collected during spring, summer, autumn and winter were preliminary characterized to determine the concentrations of ionic species, elements and organic PM (Polycyclic Aromatic Hydrocarbons, PAHs). After particle extraction from filters, the cytotoxic and pro-inflammatory effects were evaluated in human lung A549 cells. The results showed that particles collected during the colder seasons mainly induced the xenobiotic metabolizing system and the consequent antioxidant and pro-inflammatory cytokine release responses. Biological events positively correlated to PAHs and metals representative of a combustion-derived pollution. PM2.5 from the warmer seasons displayed a direct effect on cell cycle progression, suggesting possible genotoxic effects. In conclusion, a correlation between the biological effects and PM2.5 physico-chemical properties in the area of study might be useful for planning future strategies aiming to improve air quality and lower health hazards.
- 9 October 2019
- Published by MDPI AG in International Journal of Molecular Sciences
- Vol. 20 (20) , 4970
Open AccessSeasonal Variation in the Biological Effects of PM2.5 from Greater Cairo
Greater Cairo (Egypt) is a megalopolis where the studies of the air pollution events are of extremely high relevance, for the geographical-climatological aspects, the anthropogenic emissions and the health impact. While preliminary studies on the particulate matter (PM) chemical composition in Greater Cairo have been performed, no data are yet available on the PM’s toxicity. In this work, the in vitro toxicity of the fine PM (PM2.5) sampled in an urban area of Greater Cairo during 2017–2018 was studied. The PM2.5 samples collected during spring, summer, autumn and winter were preliminary characterized to determine the concentrations of ionic species, elements and organic PM (Polycyclic Aromatic Hydrocarbons, PAHs). After particle extraction from filters, the cytotoxic and pro-inflammatory effects were evaluated in human lung A549 cells. The results showed that particles collected during the colder seasons mainly induced the xenobiotic metabolizing system and the consequent antioxidant and pro-inflammatory cytokine release responses. Biological events positively correlated to PAHs and metals representative of a combustion-derived pollution. PM2.5 from the warmer seasons displayed a direct effect on cell cycle progression, suggesting possible genotoxic effects. In conclusion, a correlation between the biological effects and PM2.5 physico-chemical properties in the area of study might be useful for planning future strategies aiming to improve air quality and lower health hazards.