Hong Wang
Research Subjects
Hong Wang has a total of 10 co-authors. Here are the top co-authors by number of shared publications:
- Jia Liu
Institute of Material Medical, Shandong First Medical University & Shandong Academy of Medical Sciences, Jinan, China
1 shared publication - Qian Liu
Clinical Laboratory, China-Japan Friendship Hospital, Beijing, China
1 shared publication - Qinghui Xian
Department of Pediatrics, Jiaozhou People’s Hospital, Qingdao, China
1 shared publication - Shengbao Yang
Department of Anesthesiology, Jiaozhou People’s Hospital, Qingdao, China
1 shared publication Weihong Wu
Shandong Medical College Jinan China
1 shared publication- Weihong Wu
Shandong Medical College, Jinan, China
1 shared publication
Latest Publications
- 1 February 2021
- Published by Springer Nature in Revista Brasileira de Farmacognosia
- Vol. 31 (1) , 102-106
Development of a LC-MS/MS Method for the Quantification of Myricitrin: Application to a Pharmacokinetic Study in Rats
- 1 February 2021
- Published by Springer Nature in Revista Brasileira de Farmacognosia
- Vol. 31 (1) , 102-106
Development of a LC-MS/MS Method for the Quantification of Myricitrin: Application to a Pharmacokinetic Study in Rats
- Open Access
- 14 October 2020
- Published by Springer Nature in Revista Brasileira de Farmacognosia
- Vol. 30 (6) , 818-823
Pharmacokinetics and Tissue Distribution of Phillyrin in Rats
- 14 October 2020
- Published by Springer Nature in Revista Brasileira de Farmacognosia
- Vol. 30 (6) , 818-823
Open AccessPharmacokinetics and Tissue Distribution of Phillyrin in Rats
- 21 October 2019
- Published by Wiley in Biomedical Chromatography
- Vol. 34 (1) , e4717
Validation and application of a novel UHPLC–MS/MS method for the measurement of furanodienone in rat plasma
A sensitive ultra‐high performance liquid chromatography–tandem mass spectrometry (UHPLC–MS/MS) method was established to analyze furanodienone in rat plasma. In the process of chromatographic separation, selected reaction monitoring transitions for furanodienone and patchouli alcohol (internal standard, IS) were m/z 231.1 → 83.2 and m/z 205.1 → 95.1, respectively. Great linearity of furanodienone in plasma samples was found in the corresponding concentration range (r > 0.995). Intra‐ and inter‐day precisions (RSD, %) were <11.3% in plasma, and the accuracy (RE, %) was within ±10.7%. This method was used to the furanodienone study on rat pharmacokinetics after a single oral dose of 10 mg/kg of furanodiene. The results indicated that the maximum observed plasma concentration was 52.4 ± 19.1 ng/ml at 1.2 ± 0.7 h with an elimination half‐life of 2.2 ± 0.7 h. The obtained data indicated that furanodienone could be moderately distributed and eliminated.
- 21 October 2019
- Published by Wiley in Biomedical Chromatography
- Vol. 34 (1) , e4717
Validation and application of a novel UHPLC–MS/MS method for the measurement of furanodienone in rat plasma
A sensitive ultra‐high performance liquid chromatography–tandem mass spectrometry (UHPLC–MS/MS) method was established to analyze furanodienone in rat plasma. In the process of chromatographic separation, selected reaction monitoring transitions for furanodienone and patchouli alcohol (internal standard, IS) were m/z 231.1 → 83.2 and m/z 205.1 → 95.1, respectively. Great linearity of furanodienone in plasma samples was found in the corresponding concentration range (r > 0.995). Intra‐ and inter‐day precisions (RSD, %) were <11.3% in plasma, and the accuracy (RE, %) was within ±10.7%. This method was used to the furanodienone study on rat pharmacokinetics after a single oral dose of 10 mg/kg of furanodiene. The results indicated that the maximum observed plasma concentration was 52.4 ± 19.1 ng/ml at 1.2 ± 0.7 h with an elimination half‐life of 2.2 ± 0.7 h. The obtained data indicated that furanodienone could be moderately distributed and eliminated.