Kentaro Ouchi
Current Organizations / Institutes
The organizations/institutes from the scholar's latest article
Kentaro Ouchi has a total of 8 co-authors. Here are the top co-authors by number of shared publications:
Briony Elliott
School of Biomedical Sciences, The University of Western Australia, Perth, Australia
1 shared publication- Deirdre A. Collins
School of Population Health, Faculty of Health Sciences, Curtin University, Perth, Western Australia, Australia
1 shared publication Kazuhiro Tateda
Department of Microbiology and Infectious Diseases, Toho University School of Medicine, Tokyo, Japan
1 shared publication- Kyung Mok Sohn
Division of Infectious Diseases, Department of Internal Medicine, Chungnam National University School of Medicine, Daejeon, Korea
1 shared publication - Thomas V. Riley
School of Population Health, Faculty of Health Sciences, Curtin University, Perth, Western Australia, Australia
1 shared publication Yoshikazu Ishii
Department of Microbiology and Infectious Diseases, Toho University School of Medicine, Tokyo, Japan
1 shared publication
Latest Publications
- Open Access
- 24 December 2019
- Published by Taylor & Francis in Emerging Microbes & Infections
- Vol. 9 (1) , 42-52
Clostridioides difficile infection in the Asia-Pacific region
Clostridioides difficile causes healthcare-related diarrhoea in high-income countries. Highly resistant spores persist in healthcare facilities, primarily infecting patients who have recently received antimicrobials. C. difficile infection (CDI) has been studied in detail in North America and Europe; however, the epidemiology of CDI elsewhere, including the Asia-Pacific region, is largely unknown. A survey of CDI was performed in 13 Asia-Pacific countries. Epidemiological data on 600 cases were collected and molecular typing undertaken on 414 C. difficile isolates. Healthcare facility-associated CDI comprised 53.6% of cases, while community-associated CDI was 16.5%. The median age of cases was 63.0 years and 45.3% were female, 77.5% had used antibiotics in the previous 8 weeks, most frequently third-generation cephalosporins (31.7%), and 47.3% had used proton pump inhibitors. Recurrence (9.1%) and mortality (5.2%) rates were low, while complications including colitis or pseudomembranous colitis (13.8%), colectomy (0.4%), and toxic megacolon (0.2%) were uncommon. Common C. difficile strains were ribotypes 017 (16.7%), 014/020 (11.1%) and 018 (9.9%), with wide variation between countries. Binary toxin-positive strains of C. difficile were detected rarely. Overall, disease severity appeared mild, and mortality and recurrence were low. Continued education about, and surveillance of, CDI in Asia are required to reduce the burden of disease.
- 24 December 2019
- Published by Taylor & Francis in Emerging Microbes & Infections
- Vol. 9 (1) , 42-52
Open AccessClostridioides difficile infection in the Asia-Pacific region
Clostridioides difficile causes healthcare-related diarrhoea in high-income countries. Highly resistant spores persist in healthcare facilities, primarily infecting patients who have recently received antimicrobials. C. difficile infection (CDI) has been studied in detail in North America and Europe; however, the epidemiology of CDI elsewhere, including the Asia-Pacific region, is largely unknown. A survey of CDI was performed in 13 Asia-Pacific countries. Epidemiological data on 600 cases were collected and molecular typing undertaken on 414 C. difficile isolates. Healthcare facility-associated CDI comprised 53.6% of cases, while community-associated CDI was 16.5%. The median age of cases was 63.0 years and 45.3% were female, 77.5% had used antibiotics in the previous 8 weeks, most frequently third-generation cephalosporins (31.7%), and 47.3% had used proton pump inhibitors. Recurrence (9.1%) and mortality (5.2%) rates were low, while complications including colitis or pseudomembranous colitis (13.8%), colectomy (0.4%), and toxic megacolon (0.2%) were uncommon. Common C. difficile strains were ribotypes 017 (16.7%), 014/020 (11.1%) and 018 (9.9%), with wide variation between countries. Binary toxin-positive strains of C. difficile were detected rarely. Overall, disease severity appeared mild, and mortality and recurrence were low. Continued education about, and surveillance of, CDI in Asia are required to reduce the burden of disease.