Zeliha Candan Algun

Background: Patients with chronic kidney failure often experience reduced physical function due to inactivity and arteriovenous fistula‐related complications, negatively affecting quality of life. This study aimed to investigate the effect of intradialytic exercise on functional capacity, quality of life, fatigue, and depression in hemodialysis patients. Methods: This was a prospective, randomized controlled trial including 72 hemodialysis patients (aged 18–80 years) undergoing treatment three times per week for at least 1 year. Participants were randomly assigned to an exercise group (mean age: 55.7 ± 12.0 years) or a control group (mean age: 54.6 ± 14.2 years). The exercise group performed supervised combined aerobic and resistance exercises during dialysis sessions, three times weekly for 8 weeks, while the control group received routine hemodialysis care. Outcomes were assessed at baseline and after 8 weeks using the Six‐Minute Walk Test, Five‐Repetition Sit‐to‐Stand Test, Kidney Disease Quality of Life‐36 questionnaire, Visual Analog Scale for fatigue, Beck Depression Inventory. Results: Fifty‐nine patients completed the study (exercise group: n = 30; control group: n = 29). Both groups were similar at baseline. Post‐intervention, the exercise group demonstrated significant improvements in physical performance ( p = 0.046), quality of life subdomains ( p < 0.05), and depression ( p < 0.001), whereas no significant change was observed in functional capacity ( p = 0.627) or fatigue ( p = 0.537). In contrast, the control group demonstrated declines in several quality of life subdomains ( p < 0.05), with significant worsening in fatigue ( p = 0.011) and depression ( p = 0.011). Conclusions: Intradialytic exercise is an effective intervention to improve physical and psychological outcomes in hemodialysis patients, suggesting its integration into routine dialysis care may help mitigate progressive functional decline. Trial Registration: ClinicalTrials.gov identifier: NCT05246956

Background: The impact of structured exercise interventions on vasomotor symptoms (VMS), quality of life, and sleep disturbances in postmenopausal women is inconclusive. This study aimed to evaluate the effects of a 12-week program combining resistance and aerobic training on these outcomes. Methods: Thirty-eight postmenopausal women aged 45–65 years with moderate or severe VMS were randomized to a 12-week combined resistance and aerobic training program ( n = 20) or a control group ( n = 18). Resistance exercises using body weight were performed twice weekly, and moderate-intensity outdoor walking three times weekly. The primary outcome was the change in VMS severity from baseline to week 12, assessed by the vasomotor domain of the Menopause-Specific Quality of Life (MENQOL) questionnaire. Secondary outcomes were changes in quality of life and sleep quality assessed with the MENQOL, Menopause Rating Scale (MRS), and Pittsburgh Sleep Quality Index (PSQI). Data were analyzed using mixed-model repeated-measures ANOVA to compare within- and between-group changes. Results: Of the 38 participants enrolled, 36 completed the trial. The exercise group showed a large improvement in VMS severity (MENQOL vasomotor domain, η²=0.81, p < 0.001) and in somatic symptoms (MRS somatic domain, η²=0.62, p < 0.01). Significant improvements were also observed in the MENQOL psychosocial and physical domains, MRS psychological symptoms, and PSQI sleep quality (all p < 0.01). No significant between-group differences were found in the sexual domains of either scale ( p > 0.05). Conclusions: A combination of resistance and aerobic exercise training is an effective way to alleviate menopausal symptoms, particularly the severity of VMS, and improve mood and sleep quality in postmenopausal women. Registry: ClinicalTrials.gov, Trial registration : NCT05892094, Registration date : 17 May 2023.

Background: Motor imagery ability (MIA) is a critical cognitive process that enables the mental simulation of movements, facilitating skill acquisition in the use of myoelectric prostheses and their effective control in individuals who have undergone amputation. Although MIA is essential, its impact on upper extremity function and proprioception in myoelectric prosthesis users remains insufficiently studied. Objective: This study aims to evaluate MIA in individuals who have undergone transradial amputation and use myoelectric prostheses, compare it with a healthy control group, and examine its association with upper extremity functionality and proprioception. Methods: This cross-sectional study will include 15 individuals who have undergone transradial amputation (aged 18-65 y) and 15 age- and sex-matched healthy controls, recruited from prosthetics and orthotics centers in Istanbul, Turkey. Assessments will include MIA, hand mental rotation, upper extremity function, and proprioception. MIA will be measured using the Movement Imagery Questionnaire-3 and the Mental Chronometry Test. Hand mental rotation ability will be assessed via the Orientate mobile app. Upper extremity function will be evaluated using the Box and Block Test; Jebsen-Taylor Hand Function Test; and the Quick Disabilities of the Arm, Shoulder, and Hand questionnaire. Proprioception will be assessed through joint position sense measurements. All data will undergo appropriate statistical analyses. Results: Data collection began following funding from the Scientific and Technological Research Council of Turkey on April 25, 2025. As of November 2025, 8 participants with transradial amputation and 8 healthy controls have been recruited. Assessments are ongoing, and study completion is expected by June 2026. Conclusions: This study will evaluate MIA in individuals who have undergone transradial amputation and use myoelectric prostheses and explore its relationship with upper extremity function and proprioception. The findings are expected to guide the development of targeted rehabilitation strategies, particularly those incorporating motor imagery–based training for this population. International Registered Report Identifier (IRRID): DERR1-10.2196/83787

BACKGROUND Motor imagery ability (MIA) is a critical cognitive process that enables the mental simulation of movements, facilitating skill acquisition in the use of myoelectric prostheses and their effective control in individuals who have undergone amputation. Although MIA is essential, its impact on upper extremity function and proprioception in myoelectric prosthesis users remains insufficiently studied. OBJECTIVE This study aims to evaluate MIA in individuals who have undergone transradial amputation and use myoelectric prostheses, compare it with a healthy control group, and examine its association with upper extremity functionality and proprioception. METHODS This cross-sectional study will include 15 individuals who have undergone transradial amputation (aged 18-65 y) and 15 age- and sex-matched healthy controls, recruited from prosthetics and orthotics centers in Istanbul, Turkey. Assessments will include MIA, hand mental rotation, upper extremity function, and proprioception. MIA will be measured using the Movement Imagery Questionnaire-3 and the Mental Chronometry Test. Hand mental rotation ability will be assessed via the Orientate mobile app. Upper extremity function will be evaluated using the Box and Block Test; Jebsen-Taylor Hand Function Test; and the Quick Disabilities of the Arm, Shoulder, and Hand questionnaire. Proprioception will be assessed through joint position sense measurements. All data will undergo appropriate statistical analyses. RESULTS Data collection began following funding from the Scientific and Technological Research Council of Turkey on April 25, 2025. As of November 2025, 8 participants with transradial amputation and 8 healthy controls have been recruited. Assessments are ongoing, and study completion is expected by June 2026. CONCLUSIONS This study will evaluate MIA in individuals who have undergone transradial amputation and use myoelectric prostheses and explore its relationship with upper extremity function and proprioception. The findings are expected to guide the development of targeted rehabilitation strategies, particularly those incorporating motor imagery–based training for this population. INTERNATIONAL REGISTERED REPORT DERR1-10.2196/83787

INPLASY202570075 Effect of Stroboscopic Glasses Usage in Training and Rehabilitation: A Systematic Review and Meta-Analysis Protocol Keywords: Stroboscopic glasses, stroboscopic training, visual pe…

Background: High-intensity resistance training (HI-RT) of the quadriceps, which is one of the primary treatment methods, can aggravate the pain of knee osteoarthritis (KOA) and cause the individual to abandon the exercise

Objectives The study was conducted to investigate the effect of Yoga-based exercise program on pain, range of motion (ROM), quality of sleep, depression and quality of life in female patients with myofacial pain of temporomandibular disorders (TMD). Materials and methods 39 Female patients with myofacial pain of TMD were included in the study. Yoga based exercise program was performed to the first group and second group was control group. Visual Analog Scale (VAS), Neck Pain and Disability Scale (NPDS), neck and jaw ROM, Pittsburg Sleep Quality Index (PUQI), Beck Depression Inventory (BDI) and Short Form 36 (SF36) were evaluated. Evaluations were repeated before treatment and 6 weeks later. Results From the measurements, a decrease in Temporomandibular Joint (TMJ) (p = 0.005) and neck pain (p = 0.031) was found to be significant in favor of Yoga Group. It was also observed that the increase in ROM in the neck right lateral flexion (p = 0.001) in favor of Yoga Group. The sleep quality did not change. In yoga group, a decrease in depression level (p = 0,023) and increase Quality of life in parameters of physical function (p = 0.023), vital capacity (p = 0.026), emotional health (p = 0.002), mental health (p = 0.080) were found as significant, statistically. Conclusions It was concluded that yoga-based exercise program can be used as an alternative program in patients with myofacial pain of TMD. Further study on myofascial pain of TMD is recommended. Clinical relevance Yoga-based exercise program can be used in patients with myofascial pain due to TMD.

Pain is one of the most important factors affecting the quality of life. The quality of life can be affected in patients with Rotator Cuff Syndrome (RCS) who have pain and restricted shoulder movements. The aim of our study is to examine the effect of the pain on functional status, quality of life and physical activity levels in daily life activities of RCS patients. 40 patients (19-64 ages) with RC were included in the study. Pain severity (Visual Analogue Scale- VAS), upper extremity functional status and disability (Quick-DASH questionnaire), physical activity level (International Physical Activity Questionnaire- IPAQ) and health related quality of life (Short Form-36- SF-36) were evaluated. Statistical analyzes were made using the SPSS 25.0 program.The cases mean age was 50.40 ± 11.37 and of 26 were female and of 14 were male. In the study, significant relationship was found between the Quick-DASH score and shoulder pain at night, at rest, during activity and during heavy object carrying (p

Purpose: Hypertension (HT) can exacerbate impaired blood pressure regulation and thus increase the risk of falls. The higher incidence of HT and impaired balance in older adults may lead to the hypothesis of an association between HT and physical function in older individuals. The purpose of this study was to investigate the effects of HT on muscle strength, balance, and mobility in older adults and the relationship between them. Methods: Sixty-one older adults were included in the study and individuals with systolic blood pressure ≥140 mmHg or diastolic blood pressure ≥90 mmHg formed the Hypertensive group (n=31), while the others formed the Normotensive group (n=30). Quadriceps Femoris (QF) muscle strength was evaluated with a hand-held dynamometer, mobility was evaluated with the Timed Up and Go Test (TUG), balance performance was evaluated with the Nintendo Wii Fit Balance Board (NWBB), and physiological age was evaluated with Wii Fit Age (WFA). The systolic and diastolic blood pressure were measured before the balance test. Results: TUG and NWBB scores between groups were significantly better in the Normotensive group (p<0.05). In both Hypertensive and Normotensive groups, there was a negative correlation between QF muscle strength and TUG score, and a positive correlation between QF muscle strength and NWBB score (p<0.05). Conclusion: HT may worsen mobility and balance in older adults. Further studies are required to better understand HT and establish better appropriate interventions for older hypertensive adults.