Phuti Joanna Makgae

Obesity as directly measured by anthropometric parameters has been demonstrated to be associated with hypertension and type 2 diabetes mellitus, which are common risk factors for CVD. The study aimed at assessing the relationship between blood pressure, blood glucose and anthropometric parameters in Ellisras children. A total of 492 children aged 6 to 11 years, participated in the study. Neck circumference, waist circumference, body mass index, waist-to-height ratio, fasting blood glucose, systolic and diastolic blood pressure were measured using standard procedures. Linear regression showed significant association (P < 0.05) of anthropometric parameters (except waist-to-height ratio) with blood pressure. Fasting blood glucose was significantly associated with neck circumference when adjusted for age and gender. Positive correlation was found for systolic blood pressure with neck and waist circumference and body mass index in both genders and for diastolic blood pressure, the correlation was only found in boys. Fasting blood glucose was negatively correlated with neck circumference. Waist circumference (P = 0.025, β = 1.208, 95% CI = 1.017–1.285) was better than BMI (P = 0.046, β = 1.340, 95% CI = 1.005–1.788) in predicting elevated systolic blood pressure. These findings suggest that it is crucial to manage anthropometric parameters in the Ellisras community in order to decelerate the increase of hypertension and diabetes mellitus.

The noncommunicable diseases’ (NCDs) profile is changing rapidly from one country to another. A well-formulated cohort study in Africa could answer major questions relating to the changing profile of NCDs risk in Africa. The aim of the present study was to outline the genesis, procedures, attrition rate and major reasons for study participants to miss measurement sessions in the Ellisras Longitudinal Study (ELS). Method: The ELS followed multiple longitudinal designs comprising repeated measurements in more than one cohort with overlapping ages. Age cohort and time of measurement effects could be identified. A cluster random sampling method was used to sample 2255 participants (1201 males and 1054 females), aged 2 to 10.9 years at baseline (November 1996). Information on lifestyle (tobacco and smoking, alcohol intake, physical activity and socioeconomic status) and biological risk factors for NCD and educational achievements were collected over time. The participants were followed 17 times over the past 25 years with measurements (blood pressure and anthropometry) collected twice during the first consecutive 8 years to account for growth dynamics and other health-related variables. The attrition rate for ELS sample for boys (14%–27.3%) was significantly (p < 0.05) higher than girls (7.9%–18.6%) from May 1999 to November 2003. There was a significant (p < 0.05) increase (25.3%–70.3%) in attrition rate from November 2009 to December 2015. The ELS participant migration to urban areas provided a unique opportunity to investigate the effect of urban life on these rural young adults given the previous data collected on the same subjects at a younger age (3–10 years at baseline in 1996). Conclusion: A well-formulated ELS study in Africa could answer major questions relating to the changing magnitude of NCDs risk factor profiles in Africa.

Background: Hypertension has gained global significance and risk of cardiovascular disease, and adiposity is the most important of the conditions associated with and considered responsible for hypertension in children. Therefore, the present study aimed to determine whether indices of adiposity independently predicted blood pressure at multiple points in gender-specific groups. Methods: This was a cross-sectional study involving 10 randomly selected primary schools within the Ellisras Longitudinal Study, and involved 1816 adolescents (876 girls and 940 boys) aged 8 to 17 years. All the anthropometric indices and blood pressures (BP) were examined according to the International Society for the Advancement of Kinanthropometry protocol. Results: In an adjusted linear quantile regression analysis of boys, waist circumference (WC) was associated with BP across all multiple points of systolic blood pressure (SBP). Furthermore, the triceps skinfold site was associated with high SBP. In girls, body mass index (BMI) was significantly associated with SBP after adjustment for potential confounders. Other anthropometric indices of adiposity, including WC, biceps, and triceps skinfold sites were not associated with SBP. Conclusions: The results of the present study suggest that in black South African children, variables such as WC and triceps skinfold site may provide stronger explanatory capacity to SBP variance and systolic hypertension risk in boys than other adiposity indices; whereas in girls, only WC and BMI predict diastolic blood pressure (DBP) and SBP, respectively.

Various studies have been conducted on children using the Ellisras Longitudinal Study Survey in South Africa, but none of these has addressed growth variations of children in this rural location. The aim of this paper is to assess the age at peak height velocity using the superimposition by translation and rotation (SITAR) method for both boys and girls in rural South Africa. The study is part of the on-going Ellisras Longitudinal Study, and has employed secondary data during the period from November 1996 to November 2003. The data was collected biannually in May and November each year. The Ellisras study initially followed a cluster sampling method. All participating children underwent a series of anthropometric measurements of height and weight according to the standard procedures recommended by the International Society for the Advancement of Kinanthropometry. The analysis was done using the SITAR model. Age at peak height velocity for Ellisras rural children was at 14.45 years for boys at 11.82 years for girls. Ellisras rural girls had their age at peak height velocity way earlier than Ellisras rural boys did by an estimated 2.63 years. Ellisras rural children and their growth variations were comparable to other studies.