Yoshio Tsuboi
Current Organizations / Institutes
The organizations/institutes from the scholar's latest article
Research Subjects
Yoshio Tsuboi has a total of 6 co-authors. Here are the top co-authors by number of shared publications:
Hiroyasu Kawano
Department of Pediatrics, Fukuoka University School of Medicine, Fukuoka, Japan
1 shared publicationJiro Fukae
Department of Neurology, Fukuoka University School of Medicine, Fukuoka, Japan
1 shared publicationJun Tsugawa
Stroke center, Fukuoka University Chikushi Hospital, Fukuoka, Japan
1 shared publicationKen-Ichi Inoue
Department of Neurology, Fukuoka University School of Medicine, Fukuoka, Japan
1 shared publicationKosuke Fukuhara
Department of Neurology, Fukuoka University School of Medicine, Fukuoka, Japan
1 shared publicationShinsuke Fujioka
Department of Neurology, Fukuoka University School of Medicine, Fukuoka, Japan
1 shared publication
Latest Publications
- Open Access
- 17 March 2020
- Published by S. Karger AG in Case Reports in Neurology
- Vol. 12 (1) , 114-120
Myasthenia Gravis with Anti-Muscle-Specific Tyrosine Kinase Antibody during Pregnancy and Risk of Neonatal Myasthenia Gravis: A Case Report and Review of the Literature
A 31-year-old woman presented with a nasal voice, dysarthria, and upper limb weakness during her first pregnancy. Soon after delivery of her first baby, her symptoms disappeared. At the age of 34 years, during her second pregnancy, her nasal voice re-appeared. After delivery of the second baby, her nasal voice worsened, and bilateral eyelid ptosis and easy fatigability were also evident. She was referred to our hospital. Because of her myasthenic symptoms and anti-muscle-specific tyrosine kinase (MuSK) antibody (Ab)-positive status, she was diagnosed as having myasthenia gravis (MG). Her symptoms were worse than those in her first pregnancy. She was treated with oral steroid and double filtration plasmapheresis. After initiation of treatment, her myasthenic symptoms improved completely. In addition, her baby developed transient neonatal MG (TNMG) on the fourth day after birth and then gradually recovered over 30 days. It should be noted that symptoms of patients with anti-MuSK Ab-positive MG (MuSK-MG) can deteriorate during pregnancy, and the babies delivered of patients with MuSK-MG have a high probability of developing TNMG.
- 17 March 2020
- Published by S. Karger AG in Case Reports in Neurology
- Vol. 12 (1) , 114-120
Open AccessMyasthenia Gravis with Anti-Muscle-Specific Tyrosine Kinase Antibody during Pregnancy and Risk of Neonatal Myasthenia Gravis: A Case Report and Review of the Literature
A 31-year-old woman presented with a nasal voice, dysarthria, and upper limb weakness during her first pregnancy. Soon after delivery of her first baby, her symptoms disappeared. At the age of 34 years, during her second pregnancy, her nasal voice re-appeared. After delivery of the second baby, her nasal voice worsened, and bilateral eyelid ptosis and easy fatigability were also evident. She was referred to our hospital. Because of her myasthenic symptoms and anti-muscle-specific tyrosine kinase (MuSK) antibody (Ab)-positive status, she was diagnosed as having myasthenia gravis (MG). Her symptoms were worse than those in her first pregnancy. She was treated with oral steroid and double filtration plasmapheresis. After initiation of treatment, her myasthenic symptoms improved completely. In addition, her baby developed transient neonatal MG (TNMG) on the fourth day after birth and then gradually recovered over 30 days. It should be noted that symptoms of patients with anti-MuSK Ab-positive MG (MuSK-MG) can deteriorate during pregnancy, and the babies delivered of patients with MuSK-MG have a high probability of developing TNMG.