Mojtaba Binazadeh

The increasing consumption of pharmaceuticals, particularly antibiotics, and their discharge in used water adversely impact wastewater treatment facilities, posing a significant environmental challenge. This study investigates the removal of tetracycline from aqueous media using a novel cerium-based metal–organic framework synthesized through sonochemical techniques. The sonophotocatalyst was characterized by using infrared spectroscopy, X-ray diffraction analysis, and scanning electron microscopy. Response surface methodology was employed to optimize tetracycline removal conditions across five levels of photocatalyst loading, initial tetracycline concentration, contact time, and pH. Optimal removal conditions were achieved at pH 7, an initial tetracycline concentration of 145 ppm, a photocatalyst loading of 1307 ppm, and a contact time of 111 min, yielding an 89% removal efficiency. The synthesized Ce-MOF demonstrated stability and sustained sonophotocatalytic activity, presenting a promising solution for pharmaceutical contamination in advanced water-treatment applications.

Wastewater treatment is inevitably required to alleviate the pollution of water resources by various contaminants such as antibiotics. MOFs are novel materials with photocatalytic activities. In this study, sonophotocatalytic degradation of tetracycline (TC) by the Cerium-based MOF (Ce-MOF) is optimized by modification of its synthesis route. Ce-MOF synthesis by room temperature (RT), hydrothermal (HT), and sonochemical synthesis (SC) are studied. TC degradation experiments revealed the superiority of SC synthesis. The interplay of main synthesis parameters, namely, initial ligand concentration, ultrasound (US) power and time on sonophotocatalytic activity of Ce-MOF, were investigated by response surface methodology model (RSM) utilizing the central composite experimental design (CCD). The optimum SC synthesis conditions are an initial ligand concentration of 8.4 mmol/L, a sonication power of 50 amplitude, and a US time of 60 min. The optimally synthesized Ce-MOF was characterized by infrared spectroscopy, FTIR, XRD, FE-SEM, TEM, zeta potential analysis, diffuse reflectance spectroscopy, particle size analysis, Mott-Schottky analysis, photocurrent analysis, electrochemical impedance spectra, and photoluminescence spectroscopy. The findings indicate that the removal efficiency of TC can reach up to 81.75% within 120 min in an aqueous solution containing an initial TC concentration of 120 ppm and 1 g/L Ce-MOF at pH of 7. Mineralization efficiency of the process is 71% according to COD measurements. The Ce-MOF catalyst retained its chemical stability and remained active upon TC degradation which makes it a promising candidate for wastewater treatment.

Recent breakthroughs in the field of carbon nanotubes (CNTs) have opened up unprecedented opportunities for the development of specialized bioactive CNT‐polymers for a variety of biosensor applications. The incorporation of bioactive materials, including DNA, aptamers and antibodies, into CNTs to produce composites of bioactive CNTs has attracted considerable attention. In addition, polymers are essential for the development of biosensors as they provide biocompatible conditions and are the ideal matrix for the immobilization of proteins. The numerous applications of bioactive compounds combined with the excellent chemical and physical properties of CNTs have led to the development of bioactive CNT‐polymer composites. This article provides a comprehensive overview of CNT‐polymer composites and new approaches to encapsulate bioactive compounds and polymers in CNTs. Finally, biosensor applications of bioactive CNT‐polymer for the detection of glucose, H₂O₂ and cholesterol were investigated. The surface of CNT‐polymer facilitates the immobilization of bioactive molecules such as DNA, enzymes or antibodies, which in turn enables the construction of state‐of‐the‐art, future‐oriented biosensors.

In this study, a split-type photocatalytic membrane reactor (PMR), incorporating suspended graphitic carbon nitride (g-C3N4) as photocatalyst and a layered polymeric composite (using polyamide, polyethersulfone and polysulfone polymers) as a membrane was fabricated to remove tetracycline (TC) from aqueous solutions as the world's second most used and discharged antibiotic in wastewater. The photocatalyst was synthesised from melamine by ultrasonic-assisted thermal polymerisation method and, along with the membrane, was characterised using various methods, including Brunauer–Emmett–Teller analysis (BET), Fourier-transform infrared spectroscopy (FTIR), X-ray diffraction analysis (XRD), Field emission scanning electron microscopy (FESEM), and Ultraviolet–visible spectroscopy (UV–Vis). The PMR process was optimised, using Design-Expert software for tetracycline removal in terms of UV irradiation time, pH, photocatalyst loading, tetracycline concentration, and membrane separation iteration. It was revealed that a membrane-integrated reactor as a sustainable system could effectively produce clean water by simultaneous removal of tetracycline and photocatalyst from aqueous solution. The maximum removal of 94.8% was obtained at the tetracycline concentration of 22.16 ppm, pH of 9.78 with 0.56 g/L of photocatalyst in the irradiation time of 113.77 min after six times of passing membrane. The PMR system showed reasonable reusability by about a 25.8% drop in TC removal efficiency after seven cycles at optimal conditions. The outcomes demonstrate the promising performance of the proposed PMR system in tetracycline removal from water and suggest that it can be scaled as an effective approach for a sustainable supply of antibiotic-free clean water.

This review explores the potential of graphene oxide (GO) in enhancing the performance and energy storage capabilities as supercapacitors, where 2D GO nanosheets derived from pristine graphite, exhibit remarkable electrical conductivity, high surface area, and mechanical strength.

The COVID-19 pandemic has spurred demand for efficient and rapid diagnostic tools that can be deployed at point of care to quickly identify infected individuals. Existing detection methods are time consuming and they lack sensitivity. Point-of-care testing (POCT) has emerged as a promising alternative due to its user-friendliness, rapidity, and high specificity and sensitivity. Such tests can be conveniently conducted at the patient’s bedside. Immunodiagnostic methods that offer the rapid identification of positive cases are urgently required. Quantum dots (QDs), known for their multimodal properties, have shown potential in terms of combating or inhibiting the COVID-19 virus. When coupled with specific antibodies, QDs enable the highly sensitive detection of viral antigens in patient samples. Conventional lateral flow immunoassays (LFAs) have been widely used for diagnostic testing due to their simplicity, low cost, and portability. However, they often lack the sensitivity required to accurately detect low viral loads. Quantum dot (QD)-based lateral flow immunoassays have emerged as a promising alternative, offering significant advancements in sensitivity and specificity. Moreover, the lateral flow immunoassay (LFIA) method, which fulfils POCT standards, has gained popularity in diagnosing COVID-19. This review focuses on recent advancements in QD-based LFIA for rapid POCT COVID-19 diagnosis. Strategies to enhance sensitivity using QDs are explored, and the underlying principles of LFIA are elucidated. The benefits of using the QD-based LFIA as a POCT method are highlighted, and its published performance in COVID-19 diagnostics is examined. Overall, the integration of quantum dots with LFIA holds immense promise in terms of revolutionizing COVID-19 detection, treatment, and prevention, offering a convenient and effective approach to combat the pandemic.

Metal-organic frameworks (MOFs) have proven to be very effective carriers for drug delivery in various biological applications. In recent years, the development of hybrid nanostructures has made significant progress, including developing an innovative MOF-loaded nanocomposite with a highly porous structure and low toxicity that can be used to fabricate core-shell nanocomposites by combining complementary materials. This review study discusses using MOF materials in cancer treatment, imaging, and antibacterial effects, focusing on oral cancer cells. For patients with oral cancer, we offer a regular program for accurately designing and producing various anticancer and antibacterial agents to achieve maximum effectiveness and the lowest side effects. Also, we want to ensure that the anticancer agent works optimally and has as few side effects as possible before it is tested in vitro and in vivo. It is also essential that new anticancer drugs for cancer treatment are tested for efficacy and safety before they go into further research.