Cheng Hu

Currently, individual artificial intelligence (AI) algorithms face significant challenges in effectively diagnosing and predicting early stage emerging serious diseases. Our investigation indicates that these challenges primarily arise from insufficient clinical treatment data, leading to inadequate model training and substantial disparities among algorithm outcomes. Therefore, this study introduces an adaptive framework aimed at increasing prediction accuracy and mitigating instability by integrating various AI algorithms. In analyzing two cohorts of early cases of the coronavirus disease 2019 (COVID-19) in Wuhan, China, we demonstrate the reliability and precision of the adaptive combined learning algorithm. Employing an adaptive combination with three feature importance methods (Random Forest (RF), Scalable end-to-end Tree Boosting System (XGBoost), and Sparsity Oriented Importance Learning (SOIL)) for two cohorts, we identified 23 clinical features with significant impacts on COVID-19 outcomes. Subsequently, the adaptive combined prediction leveraged and enhanced the advantages of individual methods based on three forecasting algorithms (RF, XGBoost, and Logistic regression). The average accuracy for both cohorts exceeded 0.95, with the area under the receiver operating characteristics curve (AUC) values of 0.983 and 0.988, respectively. We established a severity grading system for COVID-19 based on the combined probability of death. Compared to the original classification, there was a significant decrease in the number of patients in the severe and critical levels, while the levels of mild and moderate showed a substantial increase. This severity grading system provides a more rational grading in clinical treatment. Clinicians can utilize this system for effective and reliable preliminary assessments and examinations of patients with emerging diseases, enabling timely and targeted treatment.

Over the last 20 years, China’s infertility rate has risen from 3% to 12.5%–15%. Infertility has become the third largest disease following cancer and cardiovascular disease. Then, the in vitro fertilization and embryo transfer (IVF-ET) becomes more and more important in infertility treatment field. However, the reported success rate for IVT-ET is 30%–40% and costs are gradually rising. Meanwhile, to increase success rates and decrease costs, the optimal selection of the IVF-ET treatment strategy is crucial. In a clinical work, the IVF-ET treatment strategy selection is always based on the experience of the doctor without a uniform standard. To solve this important and complex problem, we proposed an artificial intelligence (AI)-based optimal treatment strategy selection system to extract implicit knowledge from clinical data for new and returning patients, by mimicking the IVF-ET process and analysing a myriad of treatment decisions. We demonstrated that the performance of the model was different in 10 AI classification algorithms. Hence, we need to select the optimal method for predicting patient pregnancy result in different IVF-ET treatment strategies. Moreover, feature ranking is determined in the proposed model to measure the importance of each patient characteristics. Therefore, better advice can be provided for individual patient characteristics, doctors can provide more valid suggestions regarding certain patient characteristics to improve the accuracy of diagnosis and efficiency.

To figure out which factor contributes more on carbon emissions caused by energy consumption, this research took multisector analysis based on the Log-Mean Divisia Index Method (LMDI) and decoupling theory to assess the driving factors of carbon dioxide (CO₂) emissions in China’s six sectors from 2003 to 2016. Our empirical results reveal that China’s economy can be divided as three decoupling stages and exhibited a distinct tendency toward strong decoupling with a turning point in 2008. Thus, we discuss the impact of 2008 economic crisis on carbon emissions based on decomposition results. The empirical results of our study show the following five conclusions. (1) Most sectors in China are in weak decoupling state due to the inhibition of energy intensity on carbon emissions. (2) Different factors contribute differently to reducing emissions in different sectors, economic output has the most prominent effect, followed by energy intensity and population scale. (3) China’s current carbon emission reduction measures benefit more on energy efficiency. (4) The economic crisis has greatly reduced energy efficiency and has no significant impact on other factors. (5) If all industries adjust their energy mix, carbon emissions in China can be reduced by almost 17% every year.