Georgia Gouvi
Current Organizations / Institutes
The organizations/institutes from the scholar's latest article
Research Subjects
Research Interests
Georgia Gouvi has a total of 28 co-authors. Here are the top co-authors by number of shared publications:
- Alistair Charles Darby
Department of Infection Biology and Microbiomes, Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Liverpool, UK
1 shared publication - Amanda Choo
School of Biological Sciences, The University of Adelaide, Adelaide, Australia
1 shared publication - Carlos Cáceres
Insect Pest Control Laboratory, Joint FAO/IAEA Centre of Nuclear Techniques in Food and Agriculture, A-2444 Seibersdorf, Austria
1 shared publication - Christopher M. Ward
Australian Wine Research Institute
1 shared publication - Elisabeth Fung
School of agriculture, Food and Wine, University of Adelaide, Adelaide, Australia
1 shared publication - František Marec
Biology Centre of the Czech Academy of Sciences, Institute of Entomology, České Budějovice, Czech Republic
1 shared publication
Latest Publications
- Open Access
A generic white pupae sex selection phenotype for insect pest control
Mass releases of sterilized male insects, in the frame of sterile insect technique programs, have helped suppress insect pest populations since the 1950s. In the major horticultural pests Bactrocera dorsalis, Ceratitis capitata , and Zeugodacus cucurbitae , a key phenotype white pupae (wp) has been used for decades to selectively remove females before releases, yet the gene responsible remained unknown. Here we use classical and modern genetic approaches to identify and functionally characterize causal wp − mutations in these distantly related fruit fly species. We find that the wp phenotype is produced by parallel mutations in a single, conserved gene. CRISPR/Cas9-mediated knockout of the wp gene leads to the rapid generation of novel white pupae strains in C. capitata and B. tryoni . The conserved phenotype and independent nature of the wp − mutations suggest that this technique can provide a generic approach to produce sexing strains in other major medical and agricultural insect pests.
Open AccessA generic white pupae sex selection phenotype for insect pest control
Mass releases of sterilized male insects, in the frame of sterile insect technique programs, have helped suppress insect pest populations since the 1950s. In the major horticultural pests Bactrocera dorsalis, Ceratitis capitata , and Zeugodacus cucurbitae , a key phenotype white pupae (wp) has been used for decades to selectively remove females before releases, yet the gene responsible remained unknown. Here we use classical and modern genetic approaches to identify and functionally characterize causal wp − mutations in these distantly related fruit fly species. We find that the wp phenotype is produced by parallel mutations in a single, conserved gene. CRISPR/Cas9-mediated knockout of the wp gene leads to the rapid generation of novel white pupae strains in C. capitata and B. tryoni . The conserved phenotype and independent nature of the wp − mutations suggest that this technique can provide a generic approach to produce sexing strains in other major medical and agricultural insect pests.